Dapaturn S 50/5mg Tab

DAPATURN S 50/5MG Tablet

DAPATURN S 50/5MG Tablet, manufactured by Lupin Ltd., is a combination medication used in the management of Type 2 diabetes mellitus. It works alongside diet and exercise to help adults control their blood sugar levels.

Composition Each tablet contains:

• Dapagliflozin: 5 mg
• Sitagliptin: 50 mg

Uses DAPATURN S 50/5MG Tablet is prescribed for the following:

• Controlling elevated blood glucose levels in adults with Type 2 diabetes mellitus.
• Improving insulin sensitivity and reducing glucose production in the liver.
• Increasing glucose excretion through urine.
• Preventing serious complications of diabetes, such as eyesight loss (retinopathy), kidney damage (nephropathy), nerve damage (neuropathy), and diabetic foot ulcer.
• Treating chronic kidney disease in adults with reduced kidney function.

Dosage and Administration Take DAPATURN S 50/5MG Tablet orally as directed by your doctor, usually once daily in the morning. It can be taken with or without food. Swallow the tablet whole; do not chew, crush, or break it. For optimal benefits, it is recommended to take the medicine at the same time each day. Do not exceed the prescribed dose.

Side Effects Common side effects may include:

• Diarrhoea
• Hypoglycaemia (low blood sugar)
• Headache
• Nausea and vomiting
• Frequent urination
• Dizziness or light-headedness
• Upper respiratory tract infections, nasal congestion, or sore throat
• Genital fungal infections and urinary tract infections (UTIs)

Serious side effects are rare but can include acute pancreatitis or severe allergic reactions such as swelling of the face, tongue, lips, or itchy skin with large blisters.

Precautions

• Do not stop taking DAPATURN S 50/5MG Tablet abruptly without consulting your doctor, as this can lead to increased blood sugar levels and a higher risk of complications.
• Inform your doctor if you have kidney or liver issues, heart disease, or a history of urinary tract infections.
• The medicine is generally not recommended during pregnancy or breastfeeding.
• Avoid excessive alcohol consumption, as it may increase the risk of low blood sugar (hypoglycemia) and diabetic ketoacidosis.
• Use with caution if taking other anti-diabetic medications (e.g., insulin, sulfonylureas) due to an increased risk of hypoglycemia.
• Caution is advised when taken with diuretics, as it may increase the risk of dehydration and low blood pressure.
• Since dizziness can occur, drive only if you are alert after taking this medicine.
• DAPATURN S 50/5MG Tablet is not for individuals with Type 1 diabetes or diabetic ketoacidosis.
• Regular monitoring of blood sugar levels is crucial during treatment.

Storage Store DAPATURN S 50/5MG Tablet in a cool and dry place, away from direct sunlight, at a temperature below 30°C (or between 10ºC and 25ºC). Keep out of the sight and reach of children.

Here are frequently asked questions about DAPATURN S 50/5MG TAB, along with their concise answers:

What is Dapaturn S 50/5MG TAB used for?

Dapaturn S 50/5MG TAB is primarily used for the management of type 2 diabetes mellitus in adults. It helps to lower elevated blood sugar levels, enhance the action of insulin, and reduce the release of glucagon. This medication is typically used in conjunction with a healthy diet and regular exercise, especially when blood sugar levels are not adequately controlled by other medications like metformin alone.

How does Dapaturn S 50/5MG TAB work?

Dapaturn S 50/5MG TAB is a combination medicine containing Dapagliflozin (5 mg) and Sitagliptin (50 mg). Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that works by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion through urine and thus lowering blood sugar levels. Sitagliptin is a dipeptidyl peptidase-4 (DPP4) inhibitor that slows down the inactivation of incretin hormones, which increases insulin secretion from the pancreas and decreases glucagon release, further helping to control blood sugar.

What is the usual dosage of Dapaturn S 50/5MG TAB?

The usual dosage of Dapaturn S 50/5MG TAB is one tablet once a day, typically taken in the morning. It can be taken with or without food, but it's recommended to take it at the same time each day to maintain consistent blood sugar control. Your doctor will determine the appropriate dose based on your medical condition and response to treatment. Do not crush, chew, or break the tablet, and never exceed the prescribed dose without consulting your doctor.

What are the possible side effects of Dapaturn S 50/5MG TAB?

Common side effects of Dapaturn S 50/5MG TAB include low blood sugar (hypoglycemia), headache, upper respiratory tract infection, stuffy or runny nose, sore throat, urinary tract infections, and fungal infections in the genital area. Less common but serious side effects can include acute pancreatitis (severe and persistent stomach pain), severe allergic reactions (rash, hives, swelling of the face/tongue), and dehydration. If you experience severe or persistent side effects, or symptoms like fever, unusual tiredness, or pain in the genital area, consult your doctor immediately.

Is Dapaturn S 50/5MG TAB safe during pregnancy or breastfeeding?

No, Dapaturn S 50/5MG TAB is generally not recommended for use during pregnancy or while breastfeeding. There is limited information on its effects in pregnant women and whether it passes into human breast milk. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medicine.

Can Dapaturn S 50/5MG TAB be taken with other medications?

Dapaturn S 50/5MG TAB can interact with certain medications. Taking it with insulin or other anti-diabetic medications (like sulfonylureas) can increase the risk of low blood sugar (hypoglycemia). Diuretics (water pills) may increase the risk of dehydration and kidney problems when taken with Dapaturn S. Caution is also advised with certain antifungals (e.g., ketoconazole), antivirals (e.g., ritonavir), antibiotics (e.g., clarithromycin), and cardiac glycosides (e.g., digoxin). Always inform your doctor about all other medicines, herbal supplements, or vitamins you are currently taking to avoid potential interactions.

What precautions should be taken while using Dapaturn S 50/5MG TAB?

It's important to discuss your medical history with your doctor before starting Dapaturn S. This medicine may not be suitable if you have severe renal impairment, end-stage renal disease, or type 1 diabetes. Exercise caution if you have a history of kidney or liver problems, heart failure, low blood pressure, or urinary tract infections. Maintain good hygiene to prevent genital fungal infections, and drink plenty of fluids to prevent dehydration. Avoid excessive alcohol consumption as it can increase the risk of side effects like hypoglycemia.

What happens if a dose of Dapaturn S 50/5MG TAB is missed?

If you forget to take your dose of Dapaturn S 50/5MG TAB at the usual time, take it as soon as you remember. However, if it's nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Dapaturn S 50/5MG TAB be stored?

Dapaturn S 50/5MG TAB should be stored in a cool and dry place, away from direct sunlight, typically at room temperature (below 30°C or between 20-25°C). Keep the medicine out of the sight and reach of children.