Losanorm 25-h Tablet (10 Tab)

LOSANORM 25-H TABLET

LOSANORM 25-H TABLET, manufactured by IPCA LABORATORIES LTD., is a combination medication prescribed for the management of high blood pressure.

• Name:

  • Common Name: LOSANORM 25-H TABLET
  • Brand Name: LOSANORM 25-H

• Composition: LOSANORM 25-H TABLET contains a combination of two active ingredients:

  • Losartan (25mg): An angiotensin II receptor antagonist that works by relaxing and widening blood vessels for easier blood flow.
  • Hydrochlorothiazide (12.5mg): A thiazide diuretic (water pill) that increases urine output and prevents excess salt and fluid retention in the body.

• Uses: This medicine is primarily used for the treatment of:

  • Hypertension (high blood pressure): It helps to control blood pressure more effectively than either drug alone.
  • Prevention of stroke: Especially in patients with high blood pressure and left ventricular hypertrophy (enlarged heart muscle).
  • Reducing the risk of kidney damage in people with Type 2 diabetes (diabetic nephropathy).

• Dosage and Administration: LOSANORM 25-H TABLET should be taken in the dose and duration advised by a doctor. It can be taken with or without food, preferably at the same time each day. It is generally recommended to avoid taking it within four hours of bedtime due to its diuretic effect, which may increase urination. Do not chew, crush, or break the tablet; swallow it whole with a glass of water.

• Side Effects: Common side effects may include:

  • Dizziness
  • Headache
  • Nausea, upset stomach, or taste changes
  • Weakness or fatigue
  • Decreased blood pressure
  • Increased blood uric acid, increased blood lipid levels, glucose intolerance, and electrolyte imbalance Serious side effects, though rare, can include heart rhythm problems, muscle weakness (indicating high potassium), or allergic reactions like swelling of the face, lips, or throat.

• Precautions:

  • Pregnancy and Breastfeeding: Unsafe for use during pregnancy as it can cause fetal harm. Consult a doctor if pregnant or breastfeeding.
  • Alcohol: Avoid alcohol consumption as it can further lower blood pressure and increase the risk of side effects like dizziness.
  • Medical Conditions: Use with caution in patients with kidney or liver disease, heart conditions, diabetes, low blood pressure, or electrolyte imbalances. Not recommended for those who cannot urinate.
  • Driving: May cause dizziness, affecting the ability to drive or operate machinery.
  • Drug Interactions: Avoid potassium supplements and certain medications like Aliskiren (especially in diabetic patients) to prevent hyperkalemia or severe kidney problems.

• Storage: Store in a cool and dry place below 30°C, away from direct sunlight and moisture. Keep out of sight and reach of children.

Here are frequently asked questions about LOSANORM 25-H TABLET:

What is LOSANORM 25-H TABLET used for?

LOSANORM 25-H TABLET is primarily used to treat hypertension, also known as high blood pressure. It also helps to reduce the risk of stroke, especially in patients with an enlarged heart muscle (left ventricular hypertrophy). Additionally, it can slow down kidney damage in individuals with type 2 diabetes (diabetic nephropathy).

How does LOSANORM 25-H TABLET work?

LOSANORM 25-H TABLET is a combination medication containing Losartan and Hydrochlorothiazide. Losartan is an angiotensin II receptor blocker (ARB) that works by relaxing and widening blood vessels, allowing blood to flow more easily and thereby lowering blood pressure. Hydrochlorothiazide is a diuretic, or "water pill," which increases the production of urine and helps the body get rid of excess salt and water, reducing fluid retention and further lowering blood pressure.

What is the usual dosage for LOSANORM 25-H TABLET?

You should take LOSANORM 25-H TABLET exactly as prescribed by your doctor. It is typically taken once daily, usually in the morning, and can be consumed with or without food. The tablet should be swallowed whole and not crushed, chewed, or broken. Due to its diuretic component, it's generally advised to avoid taking it within four hours of going to bed to prevent frequent urination during the night. It may take 3-4 weeks for your blood pressure to normalize after starting the medication.

What are the possible side effects of LOSANORM 25-H TABLET?

Common side effects may include dizziness, weakness, headache, nausea, upset stomach, changes in taste, decreased blood pressure, fatigue, diarrhea, back pain, and cold/flu-like symptoms. Some individuals might also experience increased blood uric acid, higher blood lipid levels, glucose intolerance, or electrolyte imbalance. More serious, though less common, side effects that require immediate medical attention include swelling of the face, lips, throat, or tongue (indicating an allergic reaction), irregular heart rhythms, slow heart rate, muscle weakness (potentially due to high potassium levels), or swelling in the ankles, feet, or hands, and sudden weight gain (which could be signs of kidney problems).

Is LOSANORM 25-H TABLET safe during pregnancy or breastfeeding?

LOSANORM 25-H TABLET is generally considered unsafe and not recommended during pregnancy due to definite risks of harm, injury, or even death to the developing baby, including reduced amniotic fluid and underdeveloped lungs. If you become pregnant while taking this medication, stop use immediately and consult your doctor. For breastfeeding mothers, caution is advised as the medicine may pass into breast milk, and its effects on the baby are not fully known, with some data suggesting potential risks or impact on milk production.

Can LOSANORM 25-H TABLET be taken with other medications?

It is crucial to inform your doctor about all prescription, over-the-counter, herbal, and vitamin supplements you are taking. Certain medications and substances can interact with LOSANORM 25-H TABLET. You should avoid consuming alcohol as it can further lower blood pressure and increase dizziness. Also, avoid potassium supplements or salt substitutes, as they can lead to dangerously high potassium levels in the blood. Concomitant use with certain drugs like aliskiren (especially if you have diabetes or kidney problems), painkillers (NSAIDs like ibuprofen), lithium, potassium-sparing diuretics, trimethoprim, fluconazole, corticosteroids, and some heart medications like digoxin should be discussed with your doctor due to potential interactions or increased side effects.

What precautions should be taken while using LOSANORM 25-H TABLET?

Before taking LOSANORM 25-H TABLET, inform your doctor if you have kidney or liver disease, heart conditions (such as low blood pressure, history of heart attack, or aortic/mitral stenosis), diabetes, low potassium levels, electrolyte imbalances, anuria (inability to pass urine), angioedema, lupus, primary aldosteronism, or renal artery stenosis. Regular monitoring of your blood pressure and blood tests (especially for kidney function and potassium levels) may be recommended during treatment. It's important to increase your fluid intake to prevent dehydration. This medication can cause dizziness and drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. Do not stop taking the medicine abruptly without consulting your doctor, as this can lead to serious complications.

What happens if a dose of LOSANORM 25-H TABLET is missed?

If you miss a dose of LOSANORM 25-H TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this can lead to dangerously low blood pressure.

How should LOSANORM 25-H TABLET be stored?

LOSANORM 25-H TABLET should be stored in a cool and dry place, away from direct sunlight. It's recommended to store it below 30°C and keep it in its original container to protect it from light and moisture. Always keep this medicine out of the reach and sight of children and pets.