Davi-od 5tablet

DAVI-OD 5TABLET

DAVI-OD 5TABLET, manufactured by Lupin Ltd., is an oral antidiabetic medication designed to manage Type 2 Diabetes Mellitus in adults. It helps control high blood sugar levels and works to prevent serious complications associated with long-term uncontrolled diabetes, such as kidney damage, eye damage, nerve problems, and cardiovascular events.

Composition

• Active Ingredients: Each tablet contains Dapagliflozin 5 mg and Vildagliptin 100 mg.

Uses DAVI-OD 5TABLET is prescribed for the treatment of Type 2 Diabetes Mellitus. It works through a dual mechanism:

• Dapagliflozin: This is a sodium-glucose co-transporter-2 (SGLT2) inhibitor that helps the kidneys remove excess glucose from the bloodstream by increasing its excretion through urine.
• Vildagliptin: This is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases the levels of natural substances (incretins) that stimulate insulin release after meals and decrease the amount of sugar produced by the liver, thus helping to regulate blood sugar more effectively.

Dosage and Administration DAVI-OD 5TABLET should be taken orally, with or without food, as directed by your healthcare provider. Swallow the tablet whole with a glass of water; do not crush, break, or chew it. It is advisable to take the medicine at the same time each day to maintain consistent blood sugar control. Do not exceed the recommended dose or stop taking the medicine without consulting your doctor.

Side Effects Common side effects may include:

• Vomiting, nausea, abdominal pain
• Headache, dizziness
• Frequent urination, urinary tract infections
• Female genital mycotic infections (fungal infections in the genital area)
• Nasopharyngitis (common cold symptoms), upper respiratory tract infection
• Allergic reactions
• Back pain, dyslipidemia, arthralgia, influenza

Serious side effects can include dehydration, low blood sugar levels (hypoglycemia), and liver problems.

Precautions

• Allergies: Do not use DAVI-OD 5TABLET if you are allergic to dapagliflozin, vildagliptin, or any other ingredients in the formulation.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as caution is advised.
• Medical Conditions: Inform your doctor about any pre-existing conditions such as liver disease, kidney disease, heart problems, or pancreatitis, as dosage adjustments or alternative treatments may be necessary. Regular liver function tests are recommended due to the risk of liver issues.
• Alcohol: Avoid consuming alcohol while taking this medicine as it can increase the risk of hypoglycemia and lactic acidosis.
• Driving and Machinery: This medicine may cause dizziness, so exercise caution when driving or operating machinery until you know how it affects you.
• Children: DAVI-OD 5TABLET is not recommended for use in children as its safety and effectiveness have not been established.
• Drug Interactions: Inform your doctor about all other medicines, including herbal supplements, you are taking. Interactions with other antidiabetic medicines (e.g., sulfonylureas, insulin) may increase the risk of hypoglycemia. Diuretics may also increase the risk of low blood pressure.

Storage Store DAVI-OD 5TABLET in a cool and dry place, away from direct sunlight. Keep the medicine out of the sight and reach of children. It should be stored at temperatures between 10ºC to 25ºC or below 30ºC, protected from moisture and heat.

DAVI-OD 5TABLET by LUPIN LTD. is a combination medication primarily used for the management of Type 2 Diabetes Mellitus in adults. It contains two active ingredients: Dapagliflozin (5 mg) and Vildagliptin (100 mg).

Here are some frequently asked questions about DAVI-OD 5TABLET:

What is DAVI-OD 5TABLET used for?

DAVI-OD 5TABLET is prescribed to help manage blood sugar levels in adults with Type 2 Diabetes Mellitus, particularly when diet and exercise alone are not sufficient. It aims to control high blood sugar and can help prevent diabetes-related complications such as kidney damage, eye damage, nerve problems, and cardiovascular disease.

How does DAVI-OD 5TABLET work?

This medication contains two active components: Dapagliflozin and Vildagliptin. Dapagliflozin works by helping the kidneys remove excess glucose (sugar) from the bloodstream, which is then excreted through urine, thereby lowering blood sugar levels. Vildagliptin increases the levels of natural hormones called incretins, which stimulate the pancreas to release more insulin after meals and reduce the amount of sugar produced by the liver, further helping to control blood sugar.

What is the usual dosage for DAVI-OD 5TABLET?

DAVI-OD 5TABLET should be taken orally as directed by your healthcare provider. It can be taken with or without food. It is crucial to follow your doctor's instructions precisely regarding the dosage and duration of treatment, and you should not alter the dose or stop taking the medicine without consulting them.

What are the possible side effects of DAVI-OD 5TABLET?

Common side effects can include urinary tract infections (UTIs), increased urination, headaches, dizziness, nausea, nasopharyngitis (cold-like symptoms), and female genital fungal infections. More serious, but less common, side effects might include dehydration, low blood sugar levels (hypoglycemia, especially when used with other diabetes medications), and liver problems. If side effects persist or worsen, consult your doctor.

Is DAVI-OD 5TABLET safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised regarding the use of DAVI-OD 5TABLET during pregnancy. It is generally not recommended unless specifically prescribed by your doctor, who will weigh the potential benefits against the risks.

Breastfeeding: DAVI-OD 5TABLET is generally not recommended for use during breastfeeding because there is limited information on whether its components pass into human breast milk. Consult your doctor if you are breastfeeding.

Can DAVI-OD 5TABLET be taken with other medications?

DAVI-OD 5TABLET can interact with certain medications. Taking it with other oral hypoglycemic agents, such as insulin or sulfonylureas (e.g., glimepiride or glipizide), can increase the risk of low blood sugar (hypoglycemia). Diuretics (water pills) like furosemide or hydrochlorothiazide, when taken with DAVI-OD 5TABLET, may increase the risk of dehydration and low blood pressure. Additionally, using it with ACE inhibitors may increase the risk of angioedema. Always inform your doctor about all other medicines, including herbal supplements, you are currently taking to avoid potential interactions.

What precautions should be taken while using DAVI-OD 5TABLET?

You should not take DAVI-OD 5TABLET if you are allergic to dapagliflozin, vildagliptin, or any other ingredients in the tablet. Patients with severe kidney problems or those on dialysis should generally avoid this medication, and regular kidney function monitoring may be necessary. Caution is also advised for individuals with liver problems, heart conditions, or a history of pancreatitis, with regular liver function tests often recommended. It is not suitable for Type 1 diabetes or diabetic ketoacidosis. Avoid alcohol consumption while on this medication as it can increase the risk of low blood sugar and lactic acidosis. Since it may cause dizziness, exercise caution when driving or operating machinery. Maintaining good personal hygiene and staying hydrated can help prevent some common side effects. Regular monitoring of blood sugar levels is crucial during treatment.

What happens if a dose of DAVI-OD 5TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can lead to high blood sugar levels.

How should DAVI-OD 5TABLET be stored?

DAVI-OD 5TABLET should be stored in a cool and dry place, away from direct sunlight, moisture, and heat. The recommended storage temperature is below 30°C (or between 10°C to 25°C). Keep the medicine out of the sight and reach of children.