Glizid M Xr 30 Mg Tablet (10 Tab)

GLIZID M XR 30 MG TABLET

GLIZID M XR 30 MG TABLET is an oral antidiabetic medication manufactured by Mankind Pharma Ltd. It is used for the management of type 2 diabetes mellitus in adults.

• Composition GLIZID M XR 30 MG TABLET contains two active ingredients: Gliclazide (30 mg) and Metformin (500 mg). Gliclazide is a sulfonylurea that stimulates the pancreas to release more insulin. Metformin is a biguanide that works by decreasing glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

• Uses This medicine is primarily prescribed for adults with type 2 diabetes mellitus when diet, exercise, and weight reduction alone are insufficient to control blood sugar levels. It helps in lowering high blood sugar, improving overall blood sugar control, and may reduce the risk of diabetes-related complications.

• Dosage and Administration GLIZID M XR 30 MG TABLET is typically taken once daily, preferably with the morning meal, or as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water and should not be crushed, chewed, or broken, as this can affect its extended-release mechanism. Consistent timing is essential for stable blood sugar management. Dosage adjustments are made by a doctor based on individual blood glucose levels, with the maximum recommended daily dose of gliclazide not exceeding 60mg.

• Side Effects Common side effects may include hypoglycemia (low blood sugar), nausea, vomiting, diarrhea, abdominal pain, headache, taste disturbance, and loss of appetite. More serious, though rare, side effects can include lactic acidosis, changes in liver function, and long-term use may lead to vitamin B12 deficiency.

• Precautions GLIZID M XR 30 MG TABLET is generally not recommended for individuals with type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, or during pregnancy and breastfeeding. Alcohol consumption should be avoided or minimized due to an increased risk of hypoglycemia and lactic acidosis. Caution is advised for patients with heart disease or other conditions causing tissue hypoxia. It may interact with other medications, including certain anti-diabetic drugs, beta-blockers, and corticosteroids. Regular monitoring of blood sugar, kidney function, liver function, and vitamin B12 levels is often advised. Do not stop taking the medicine abruptly without consulting a doctor.

• Storage Store GLIZID M XR 30 MG TABLET in a cool and dry place, away from direct sunlight, at temperatures typically below 25°C or 30°C. Keep out of the sight and reach of children.

What is Glizid M XR 30 Tablet used for?

Glizid M XR 30 Tablet is primarily used to manage Type 2 diabetes mellitus in adults. It is prescribed when diet, exercise, and weight reduction alone are insufficient to control blood sugar levels. This medication helps in improving blood sugar control and can also reduce the risk of diabetes-related complications such as kidney damage, blindness, nerve problems, heart disease, or stroke.

How does Glizid M XR 30 Tablet work?

Glizid M XR 30 Tablet is a combination of two anti-diabetic drugs: Gliclazide and Metformin. Gliclazide works by stimulating the beta cells in the pancreas to release more insulin. Metformin, on the other hand, reduces the amount of glucose produced by the liver, delays glucose absorption from the intestines, and improves the body's response to insulin. This dual action helps to lower and keep blood sugar levels in check.

What is the usual dosage for Glizid M XR 30 Tablet?

The dosage of Glizid M XR 30 Tablet is determined by your doctor based on your individual medical condition, blood sugar levels, and response to treatment. It is typically taken once daily, preferably with your morning meal, or as prescribed by your doctor. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken, as this can affect its extended-release mechanism. Consistent timing is essential for maintaining stable blood sugar levels.

What are the possible side effects of Glizid M XR 30 Tablet?

Common side effects can include hypoglycemia (low blood sugar levels), which may cause dizziness, sweating, palpitations, hunger pangs, and a dry mouth. Other common side effects are gastrointestinal disorders like nausea, vomiting, stomach pain or indigestion, diarrhoea, and constipation. Headache and taste disturbance are also reported. Serious but rare side effects can include lactic acidosis and, with long-term use, vitamin B12 deficiency.

Is Glizid M XR 30 Tablet safe during pregnancy or breastfeeding?

Glizid M XR 30 Tablet is generally not recommended during pregnancy as it can harm the unborn baby, and insulin is often preferred for managing diabetes in pregnant women. For breastfeeding women, it is contraindicated because it may pass into breast milk and potentially harm the newborn. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can Glizid M XR 30 Tablet be taken with other medications?

Glizid M XR 30 Tablet can interact with other medications, potentially altering the treatment response. It is crucial to inform your doctor about all prescribed or non-prescribed medicines, herbal supplements, and vitamins you are taking. Interactions can occur with medicines like beta-blockers, certain cationic medicines (e.g., amiloride, digoxin), corticosteroids, other anti-diabetic medications (including insulin), and diuretics.

What precautions should be taken while using Glizid M XR 30 Tablet?

Avoid alcohol consumption while taking this medicine as it can increase the risk of low blood sugar (hypoglycemia) and lactic acidosis. Inform your doctor if you have a history of heart, liver, or kidney diseases, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or hemolytic anemia. Regular monitoring of blood sugar levels is essential. Be aware of symptoms of low blood sugar and carry a source of sugar with you.

What happens if a dose is missed?

If you miss a dose of Glizid M XR 30 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this can cause a dangerous drop in blood glucose levels. Missing a dose can lead to high blood sugar levels.

How should it be stored?

Glizid M XR 30 Tablet should be stored in a cool and dry place, away from direct sunlight. Keep it out of sight and reach of children. It should be stored at temperatures between 10ºC to 25ºC or below 30ºC.