Supirocin Cream 10 G

SUPIROCIN CREAM 10 G

SUPIROCIN CREAM 10 G, manufactured by Glenmark Pharmaceuticals Ltd., is a topical antibiotic medication used to treat various bacterial skin infections.

• Name:

  • Brand Name: SUPIROCIN CREAM
  • Common Name: Mupirocin Cream

• Composition:

  • Active Ingredient: Mupirocin 2% w/w (as calcium)

• Uses: SUPIROCIN CREAM is prescribed for the treatment of bacterial skin infections. It is effective against organisms such as Staphylococcus aureus and Streptococcus pyogenes. Specific conditions it treats include:

  • Impetigo
  • Folliculitis
  • Boils
  • Small cuts, abrasions, and sutured wounds that have become infected
  • Secondarily infected traumatic skin lesions The cream works by inhibiting bacterial protein synthesis, thereby killing the infection-causing bacteria and preventing their growth. It is not effective against fungal or viral infections.

• Dosage and Administration: SUPIROCIN CREAM is for external use only.

  • Typical Dosage: Apply a small amount to the affected area three times daily.
  • Duration: Treatment usually lasts for up to 10 days. It is important to complete the full course of treatment, even if symptoms improve, to prevent antibiotic resistance.
  • Application: Wash hands before and after applying the cream. The treated area may be covered with a sterile gauze dressing if desired.
  • Caution: Do not use larger amounts or apply more frequently or for a longer duration than directed.

• Side Effects: Most side effects are minor and temporary.

  • Common Side Effects: Burning, itching, redness, stinging, and dryness at the application site.
  • Less Common/Rare Side Effects: Rash, swelling, skin hypersensitivity, contact dermatitis, increased exudate, nausea, and vomiting.
  • Serious Side Effects: Allergic reactions (e.g., shortness of breath, wheezing, difficulty breathing, swelling of the face, lips, tongue, or other body parts, severe rash) require immediate medical attention. In rare cases, inflammation of the colon (pseudomembranous colitis) causing diarrhea, stomach pain, and fever may occur.

• Precautions:

  • Allergies: Do not use if allergic to Mupirocin or any of the cream's ingredients.
  • Application Sites: Avoid use in or near the eyes, nostrils, mouth, or for vaginal application. Rinse thoroughly with water if accidental contact occurs.
  • Damaged Skin: Use with caution on broken skin, extensive wounds, or burns, especially in patients with moderate to severe renal failure, due to potential absorption of polyethylene glycol.
  • Antibiotic Resistance: Prolonged use can lead to the overgrowth of non-susceptible organisms, including fungi, and can increase antibiotic resistance.
  • Pediatric Use: Not recommended for infants younger than 2 months. For children under 2 years, use only if instructed by a doctor.
  • Pregnancy and Breastfeeding: Use during pregnancy only if clearly needed. Consult a doctor if breastfeeding; if applied to cracked nipples, wash well before feeding.
  • Drug Interactions: Interactions with other systemic or topical drugs have not been extensively studied, but due to poor systemic absorption, interactions with systemic agents are unlikely. Do not mix with other preparations as they may prevent SUPIROCIN from working.

• Storage:

  • Store below 25°C in a cool and dry place.
  • Do not freeze.
  • Keep away from direct sunlight, heat, moisture.
  • Keep out of sight and reach of children.

SUPIROCIN CREAM 10 G: Frequently Asked Questions

SUPIROCIN Cream, manufactured by Glenmark Pharmaceuticals Ltd., is a topical antibiotic medication containing mupirocin as its active ingredient. It is used to treat various bacterial skin infections.

What is SUPIROCIN Cream used for?

SUPIROCIN Cream is primarily used to treat bacterial skin infections such as impetigo (a highly contagious skin infection), folliculitis (skin swelling around hair roots), boils, infected minor cuts, abrasions, and sutured wounds. It helps eliminate bacterial colonies and can also be used for prophylaxis of catheter exit-site infections and antibiotic prophylaxis of skin surgery.

How does SUPIROCIN Cream work?

SUPIROCIN Cream works by stopping the growth of infection-causing bacteria on the skin. Its active ingredient, mupirocin, is an antibiotic that inhibits bacterial protein synthesis by reversibly binding to bacterial isoleucyl transfer-RNA synthetase. This action prevents the essential proteins needed for bacterial survival from being produced, thereby killing the bacteria and preventing the infection from spreading.

What is the usual dosage for SUPIROCIN Cream?

A small amount of SUPIROCIN Cream should be applied to the affected area three times daily. The treated area may be covered with a gauze dressing if desired. Treatment typically lasts for up to 10 days, but it is important to follow your doctor's instructions regarding the duration of use. Do not stop treatment early, even if symptoms improve, to ensure the infection is fully cleared.

What are the possible side effects of SUPIROCIN Cream?

Common side effects include local reactions at the application site such as burning, stinging, itching, pain, redness, dry skin, and swelling. Less common but more serious side effects can include allergic reactions (rash, hives, wheezing, swelling of lips/mouth, difficulty breathing, fainting). If you experience severe side effects or an allergic reaction, wipe off the cream, stop using it, and seek immediate medical attention.

Is SUPIROCIN Cream safe during pregnancy or breastfeeding?

Pregnancy: SUPIROCIN Cream is generally considered safe for use during pregnancy if clearly needed and prescribed by a doctor. Animal studies have shown low or no adverse effects to the developing baby, but human studies are limited.

Breastfeeding: Use SUPIROCIN Cream with caution while breastfeeding. It is unclear if it passes into breast milk. If applied to a cracked nipple, thoroughly wash the nipple before breastfeeding to prevent ingestion by the infant. Due to low systemic absorption (less than 1%) after topical application, significant excretion into breast milk is unlikely.

Can SUPIROCIN Cream be taken with other medications?

Interactions between topical mupirocin and other systemic or topical drugs have not been extensively studied, but drug interactions with systemic agents are unlikely due to very poor absorption through the skin. However, do not mix SUPIROCIN Cream with any other preparation, as this may prevent it from working effectively. Always inform your doctor or pharmacist about all medicines, vitamins, or supplements you are taking.

What precautions should be taken when using SUPIROCIN Cream?

SUPIROCIN Cream is for external use only. Avoid applying it to the eyes, nostrils, mouth, or near tubes inserted into your body (cannulae). If it accidentally gets into your eyes, wash them thoroughly with water. Do not apply to extensive open wounds or burns, especially if you have moderate to severe renal failure, as polyethylene glycol in the ointment can be absorbed. Prolonged use may lead to the overgrowth of non-susceptible organisms or fungi. Discontinue use if irritation or severe allergic reaction occurs.

What happens if a dose of SUPIROCIN Cream is missed?

If you forget an application, apply it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.

How should SUPIROCIN Cream be stored?

Store SUPIROCIN Cream below 25°C in a cool, dry place, away from moisture, heat, and direct sunlight. Do not freeze. Keep the tube tightly closed and out of sight and reach of children.