Dinofirst Tablet (15 Tab)

DINOFIRST TABLET

Dinofirst Tablet is a prescription medication manufactured by Akumentis Healthcare Ltd.

Composition Dinofirst Tablet contains Dienogest (2 mg) as its active ingredient. Dienogest is a progestin, a type of female hormone similar to progesterone.

Uses Dinofirst Tablet is primarily used for the management of pelvic pain associated with endometriosis. Endometriosis is a condition where tissue similar to the lining of the uterus grows outside the uterus, causing pain and other symptoms. It works by suppressing the production of estradiol, a hormone that promotes the abnormal growth of endometrial tissue. By reducing estradiol levels, Dinofirst Tablet helps shrink endometrial tissue, relieve pain, and regulate heavy bleeding. It can also help manage other symptoms of endometriosis, including lower abdominal pain, period pain, pain during and after sexual intercourse, constipation, diarrhea, and nausea.

Dosage and Administration The typical dosage guidance is one tablet daily, taken orally. It can be taken with or without food, but it is advised to take it at the same time each day for maximum benefit. The course duration is often around 4 weeks, and treatment should be continued as prescribed by a doctor, even during menstrual periods.

Side Effects Common side effects associated with Dinofirst Tablet include:

• Headache or migraine
• Acne
• Breast discomfort or pain
• Nausea or vomiting
• Weight gain
• Depressed mood, mood changes, nervousness, irritability
• Sleep difficulties
• Loss of sex drive (libido)
• Abdominal pain or swollen stomach
• Hair loss
• Back pain
• Ovarian cysts or hot flushes
• Uterine or vaginal bleeding, including spotting These side effects usually do not last long and may resolve once treatment is completed. If they worsen or persist, medical advice should be sought.

Precautions

• Pregnancy and Breastfeeding: Dinofirst Tablet can have severe effects if taken during pregnancy and is not recommended for pregnant women. It can cause moderate side effects in breastfeeding women, and caution is advised.
• Medical Conditions: It is strongly recommended to avoid Dinofirst Tablet in conditions like heart disease, breast cancer, and high blood pressure. Caution is advised for children and adolescents (12 to 18 years old) as it may affect bone strength.
• Drug and Food Interactions: Consumption of grapefruit juice is not recommended as it may increase the risk of side effects. Severe interactions with some other medicines are possible.
• Allergies: Do not take Dinofirst Tablet if you are allergic to any of its components.
• Overdose: In case of a suspected overdose, immediate medical attention should be sought.
• Driving: Dinofirst Tablet is generally considered safe for driving and operating machinery as it is not associated with drowsiness or sleepiness.
• Addiction: This medicine is not addictive.

Storage Dinofirst Tablet should be stored in a cool and dry place, away from direct sunlight. It should be kept out of reach and sight of children. The recommended storage temperature is between 10ºC to 25ºC or below 30ºC.

What is DINOFIRST TABLET used for?

DINOFIRST TABLET is primarily used for the management of painful symptoms associated with endometriosis. Endometriosis is a condition where tissue similar to the lining of the uterus grows outside the uterus, causing pelvic pain and other symptoms. It can help reduce lower abdominal pain, period pain, discomfort during and after sex, and bowel problems like constipation and diarrhea associated with endometriosis.

How does DINOFIRST TABLET work?

DINOFIRST TABLET contains Dienogest, which is a type of progestogen, a synthetic form of the female hormone progesterone. It works by suppressing the production of estradiol, a hormone that stimulates the growth of endometrial tissue. By reducing estradiol levels, Dinofirst Tablet helps to shrink endometrial tissue, preventing its abnormal growth and relieving the associated pain and discomfort.

What is the usual dosage of DINOFIRST TABLET?

The usual dosage of DINOFIRST TABLET is one tablet once daily. It can be taken with or without food, but it is recommended to take it at the same time every day for consistent effectiveness. The treatment can be started from the first day of the menstrual cycle without a break and should be continued for the duration prescribed by your doctor.

What are the possible side effects of DINOFIRST TABLET?

Common side effects of DINOFIRST TABLET include acne, headache, mood changes, breast discomfort, nausea, vomiting, abdominal pain, weight gain, and ovarian cysts. You may also experience abnormal or irregular menstrual bleeding patterns. More serious, though less common, side effects can include decreased bone mineral density with long-term use and liver damage. If any side effects persist or worsen, consult your doctor.

Is DINOFIRST TABLET safe during pregnancy or breastfeeding?

DINOFIRST TABLET is not recommended for use during pregnancy as it may cause serious side effects. Women of childbearing age should use a non-hormonal (physical/barrier) method of contraception while taking this medicine, and hormonal contraceptives should not be used. It is also not recommended for use during breastfeeding, as limited human data suggests the drug may pass into breast milk and harm the baby.

Can DINOFIRST TABLET be taken with other medications?

DINOFIRST TABLET can interact with certain medications. It is important to inform your doctor about all medicines, supplements, and herbal products you are currently taking or plan to take. Specifically, discuss the use of antifungals (e.g., fluconazole, ketoconazole), anti-infectives (e.g., rifampicin, erythromycin), medicines for brain-related disorders, medicines to reduce stomach acid, medicines for high blood pressure, anti-HIV medicines, and anticonvulsants (e.g., phenytoin, carbamazepine). Hormonal contraceptives should be discontinued while on Dinofirst Tablet.

What precautions should be taken with DINOFIRST TABLET?

Before taking DINOFIRST TABLET, inform your doctor if you have or have had liver, kidney, or heart problems, diabetes, undiagnosed vaginal bleeding, a history of breast cancer, or blood clotting disorders. Long-term use of this medicine can potentially reduce bone mineral density, so your doctor may monitor this. This medicine is not recommended for children who have not had their first period.

What happens if a dose of DINOFIRST TABLET is missed?

If you miss a dose of DINOFIRST TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should DINOFIRST TABLET be stored?

DINOFIRST TABLET should be stored in a cool and dry place, away from direct sunlight, heat, and moisture. Keep it in its original packaging and out of the reach of children and pets. Ensure the package is not left open as this might affect the medicine's effectiveness.