Nitrofix Sr 30 Mg Tablet (10 Tab)

NITROFIX SR 30 MG TABLET is a medication primarily used for the long-term prevention and management of angina pectoris, a type of chest pain caused by reduced blood flow to the heart. It is not intended for treating acute angina attacks.

• Name:

  • Brand Name: NITROFIX SR 30 MG TABLET
  • Common Name: Isosorbide Mononitrate (sustained-release)

• Composition:

  • Each tablet contains Isosorbide Mononitrate 30 mg as the active ingredient. This medication belongs to a class of drugs known as nitrates.

• Uses:

  • Prevention of angina pectoris (chest pain) by relaxing and widening blood vessels, which improves blood flow and oxygen supply to the heart and reduces its workload.

• Dosage and Administration:

  • Take exactly as prescribed by your doctor.
  • Swallow the tablet whole with a glass of water; do not break, chew, or crush it, as it is a sustained-release formulation.
  • Maintain a consistent dosing schedule to ensure effectiveness and prevent the development of tolerance.
  • Do not alter the dosage or discontinue the medicine without consulting your doctor, as abrupt cessation can worsen anginal symptoms.

• Side Effects:

  • Common: Headache, dizziness, lightheadedness, flushing (warmth or redness), nausea, and fainting. Headaches often subside after a few days of continued treatment.
  • Serious (Overdose): Symptoms may include pulsating headache, reddening of the skin, blurred vision, a sudden drop in blood pressure, and severe dizziness or fainting. Seek immediate medical attention if an overdose is suspected.

• Precautions:

  • Avoid if allergic to isosorbide mononitrate or if you have severe low blood pressure, severe anemia, hypertrophic cardiomyopathy, or certain heart conditions.
  • Drug Interactions: Do not take with phosphodiesterase inhibitors (e.g., sildenafil, tadalafil) used for erectile dysfunction, as this can cause a dangerous drop in blood pressure.
  • Alcohol: Limit or avoid alcohol consumption as it may increase side effects like dizziness and low blood pressure.
  • Special Populations: Use with caution during pregnancy and breastfeeding; consult your doctor. Caution is also advised for individuals with liver or kidney issues, glaucoma, or those who have recently experienced a head injury or stroke.
  • May cause dizziness or lightheadedness, so avoid driving or operating heavy machinery until you know how the medicine affects you.

• Storage:

  • Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children and pets.

What is NITROFIX SR 30 MG TABLET used for?

NITROFIX SR 30 MG TABLET is primarily used for the prevention and management of angina pectoris, which is a type of chest pain caused by reduced blood flow to the heart muscle due to narrowed blood vessels. It is not intended to treat an acute angina attack that has already begun, as its onset of action is not sufficiently rapid for this purpose.

How does NITROFIX SR 30 MG TABLET work?

NITROFIX SR 30 MG TABLET contains Isosorbide Mononitrate as its active ingredient. This component works by releasing nitric oxide in the body, which helps to relax and widen blood vessels, a process known as vasodilation. This vasodilation improves blood flow and oxygen supply to the heart, thereby reducing the heart's workload and helping to prevent angina attacks.

What is the usual dosage for NITROFIX SR 30 MG TABLET?

The usual starting dose for adults is typically 30 mg, taken once daily in the morning. Your doctor may adjust the dosage based on your response to treatment and individual needs, with doses potentially increasing to 120 mg or, rarely, 240 mg daily. The tablet should be swallowed whole with a glass of water and should not be broken, chewed, or crushed, as it is a sustained-release formulation. It can be taken with or without food.

What are the possible side effects of NITROFIX SR 30 MG TABLET?

Common side effects include headache, dizziness, lightheadedness, flushing (a warm, red feeling in the face, neck, or chest), and nausea. Headaches often subside after a few days of continued treatment. Other possible side effects can include fainting, irregular heartbeat, low blood pressure, abdominal pain, diarrhea, and allergic reactions such as rash, itching, or swelling. If any side effects persist or worsen, it is important to consult your doctor.

Is NITROFIX SR 30 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised when considering NITROFIX SR 30 MG TABLET during pregnancy, as there is limited information on its effects. It is crucial to consult your doctor to discuss the potential risks and benefits before taking this medicine if you are pregnant or planning to become pregnant. Breastfeeding: Precautions are necessary while breastfeeding, as the safety of NITROFIX SR 30 MG TABLET is not well-established, and it may pass into breast milk. Your doctor may recommend discontinuing breastfeeding during treatment. Always consult your doctor for advice on using this medication while breastfeeding.

Can NITROFIX SR 30 MG TABLET be taken with other medications?

NITROFIX SR 30 MG TABLET can interact with certain medications. It is contraindicated and should not be taken with erectile dysfunction medications (PDE-5 inhibitors) such as sildenafil, tadalafil, or vardenafil, as this combination can cause a dangerous and severe drop in blood pressure. Caution should also be exercised when taken with other blood pressure-lowering medications, as it may enhance their effects. Always inform your doctor about all prescription and non-prescription medicines, herbals, and supplements you are currently taking to avoid potential interactions.

What precautions should be taken while using NITROFIX SR 30 MG TABLET?

It is recommended to avoid or limit alcohol consumption while taking this medication, as it can increase the risk of dizziness, lightheadedness, and a significant drop in blood pressure. This medicine may cause dizziness or sleepiness, so it is advisable to avoid driving or operating heavy machinery until you understand how it affects you. Inform your doctor if you have pre-existing conditions such as low blood pressure, glaucoma, liver disease, kidney disease, a recent heart attack or stroke, severe anemia, or hypertrophic cardiomyopathy. Do not stop taking NITROFIX SR 30 MG TABLET abruptly, as this can worsen your angina symptoms. To maintain its effectiveness and prevent tolerance, it is crucial to stick to a consistent dosing schedule as prescribed by your doctor.

What happens if a dose of NITROFIX SR 30 MG TABLET is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. Always consult your doctor before making any changes to your dosage.

How should NITROFIX SR 30 MG TABLET be stored?

NITROFIX SR 30 MG TABLET should be stored in a cool, dry place at a temperature not exceeding 30°C. It should be kept in its original packaging and protected from light and moisture. Ensure it is kept out of the reach of children and pets.