DOMSTAL MT 10 MG TABLET

Domstal MT 10 mg Tablet, manufactured by Torrent Pharmaceuticals Ltd., is an anti-emetic and prokinetic medication.

Composition

The tablet contains Domperidone 10 mg as its active ingredient.

Uses

Domstal MT 10 mg Tablet is primarily used to treat:

• Nausea and vomiting in adults and adolescents aged 12 years or older, weighing 35 kg or more.
• Indigestion (dyspepsia) and associated symptoms like bloating, fullness, and gastric discomfort.
• Gastroparesis (delayed gastric emptying).
• Nausea and vomiting caused by motion sickness, migraine, chemotherapy, or radiotherapy. It may also be prescribed in certain cases to aid in managing post-operative nausea and vomiting and, occasionally, to boost milk production if other options have been unsuccessful.

Dosage and Administration

Take Domstal MT 10 mg Tablet as advised by your physician, typically half an hour before each meal. For dispersible tablets, dissolve in the prescribed amount of water and consume immediately. Do not crush, chew, or break the tablet. It is recommended to take the lowest effective dose for the shortest duration, generally not exceeding seven days, unless directed by a doctor.

Side Effects

Common side effects include:

• Dry mouth
• Headache
• Stomach pain
• Diarrhea
• Dizziness or sleepiness More serious, though less common, side effects include an increased risk of heart rhythm disorders (arrhythmia) and cardiac arrest, especially in individuals over 60 years of age or those taking doses higher than 30 mg daily.

Precautions

• Contraindications: Do not take if allergic to domperidone, or if you have moderate to severe liver disease, certain heart conditions (like QTc prolongation), bleeding/blockage/tear in the intestines, or a pituitary gland tumor (prolactinoma). It is not recommended for children under 12 years or weighing less than 35 kg, or for breastfeeding women.
• Warnings: Use with caution in patients with kidney disease; dose adjustments may be necessary. Inform your doctor about any pre-existing heart conditions or if you are over 60 years old due to the increased risk of cardiac issues.
• Interactions: Avoid alcohol, as it can worsen side effects. Inform your doctor about all other medications you are taking, especially antifungals (e.g., ketoconazole), certain antibiotics (e.g., erythromycin), or antacids, as these can interact with Domstal MT.
• Pregnancy: Consult your doctor before use if you are pregnant or planning to conceive.
• Driving: This medicine may cause dizziness or sleepiness; avoid driving or operating machinery until you know how it affects you.

Storage

Store the medicine in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. The typical storage temperature is below 30°C.

DOMSTAL MT 10 MG TABLET FAQs

What is DOMSTAL MT 10 MG Tablet used for?

DOMSTAL MT 10 MG Tablet is primarily used to manage nausea and vomiting. It also helps in relieving symptoms associated with indigestion, such as bloating, fullness, and gastric discomfort. Additionally, it can be used for symptoms related to gastroparesis (slow stomach emptying), motion sickness, and nausea/vomiting caused by certain medications, chemotherapy, radiotherapy, or migraines.

How does DOMSTAL MT 10 MG Tablet work?

DOMSTAL MT 10 MG Tablet contains Domperidone, which is a dopamine antagonist and a prokinetic agent. It works by blocking dopamine D2 receptors in the brain's chemoreceptor trigger zone (CTZ), which reduces signals that lead to nausea and vomiting. It also enhances the movement of the gastrointestinal tract, speeding up stomach emptying and improving the passage of food through the stomach and intestines.

What is the usual dosage for DOMSTAL MT 10 MG Tablet?

The dosage and duration of DOMSTAL MT 10 MG Tablet should be precisely as advised by your doctor. Generally, for adults and adolescents 16 years and older, it can be up to 10 mg three times daily and at night for symptoms of post-prandial stomach discomfort, with a maximum duration of 2 weeks. For nausea and vomiting, it can be up to 10 mg three times daily and at night for a maximum duration of 48 hours. The tablet is typically taken half an hour before meals, preferably on an empty stomach. It's designed to melt in the mouth or be dispersed in a teaspoonful of water before administration.

What are the possible side effects of DOMSTAL MT 10 MG Tablet?

Common side effects include dry mouth, headache, stomach pain, diarrhea, and drowsiness. If these side effects persist or worsen, it is important to consult your doctor. In rare cases, it may be associated with an increased risk of heart problems like irregular heartbeat, especially in individuals over 60 years or those taking higher doses or certain other medications.

Is DOMSTAL MT 10 MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised when taking DOMSTAL MT 10 MG Tablet during pregnancy. It should be used only if considered clearly necessary by your doctor, who will weigh the benefits against potential risks. Breastfeeding: DOMSTAL MT 10 MG Tablet is generally not recommended for breastfeeding women as small amounts of the medicine may pass into breast milk and could cause unwanted side effects in a breastfed baby. However, in some cases, a doctor might prescribe it to increase milk supply if other measures have not been effective, and if they deem it necessary.

Can DOMSTAL MT 10 MG Tablet be taken with other medications?

It is crucial to inform your doctor about all other medications you are taking, as DOMSTAL MT 10 MG Tablet can interact with various drugs. Concomitant use with certain antifungals (e.g., ketoconazole, fluconazole, voriconazole) and antibiotics (e.g., erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine) is generally not recommended due to potential interactions. It also interacts with some medicines for heart problems, high blood pressure (e.g., amiodarone, dronedarone, quinidine), psychoses (e.g., haloperidol, pimozide), and depression (e.g., citalopram, escitalopram).

What precautions should be taken with DOMSTAL MT 10 MG Tablet?

Avoid driving or operating heavy machinery if you experience drowsiness, dizziness, or reduced alertness after taking this medicine. Do not consume alcohol, as it can worsen side effects. Inform your doctor if you have liver, kidney, or heart conditions (including known QTc prolongation or underlying heart conditions), or a history of bleeding ulcers, obstruction, or perforation in the stomach or intestines. It is not recommended for children under 12 years or weighing less than 35 kg.

What happens if a dose is missed?

If you miss a dose of DOMSTAL MT 10 MG Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should DOMSTAL MT 10 MG Tablet be stored?

Store DOMSTAL MT 10 MG Tablet in a cool and dry place, below 30°C, away from direct sunlight, moisture, and out of the sight and reach of children.