Rabicip D Capsule (15 Cap)

RABICIP D CAPSULE (15 CAP) by CIPLA LTD.

RABICIP D CAPSULE is a combination medication used to treat various gastrointestinal conditions.

• Name:

  • Brand Name: RABICIP D CAPSULE
  • Common Name: Rabeprazole and Domperidone Capsules

• Composition:

  • Each hard gelatin capsule contains:
    • Rabeprazole Sodium IP 20mg (as enteric-coated pellets)
    • Domperidone IP 30mg (as sustained-release pellets)

• Uses: RABICIP D CAPSULE is primarily prescribed for the treatment of:

  • Gastroesophageal Reflux Disease (GERD) and its symptoms like heartburn and acid reflux
  • Peptic Ulcer Disease
  • Zollinger-Ellison Syndrome
  • Relief from nausea and vomiting
  • Improvement of digestion

• Dosage and Administration: Typically, one capsule is taken once daily, preferably in the morning before the first meal. The capsule should be swallowed whole with a glass of water and not crushed or chewed. Dosage may vary based on the patient's condition and response to treatment.

• Side Effects: Common side effects include headache, dizziness, dry mouth, abdominal pain, diarrhea, nausea, vomiting, and flatulence. If severe side effects such as rash, swelling, or difficulty breathing occur, immediate medical attention is advised.

• Precautions:

  • Avoid alcohol consumption as it may increase the risk of dizziness and drowsiness.
  • Inform your doctor about any existing medical conditions, especially liver or kidney disease, heart problems (like prolonged QT interval or electrolyte disturbances), or stomach/intestinal bleeding/obstruction.
  • Caution is advised during pregnancy and breastfeeding; consult a doctor.
  • May interact with certain medications, including blood thinners, antifungals, anti-HIV drugs, and anti-cancer medications.
  • Prolonged use may lead to Vitamin B12 deficiency and low levels of calcium, magnesium, and Vitamin D, potentially increasing the risk of osteoporosis.
  • Not recommended for children below 5 or 16 years of age in some instances.

• Storage: Store RABICIP D CAPSULE at room temperature, ideally below 25°C or 30°C. Keep it in a cool, dry place, away from moisture, heat, direct sunlight, and out of reach of children and pets.

What is RABICIP D CAPSULE used for?

RABICIP D CAPSULE is primarily used to treat gastroesophageal reflux disease (GERD), also known as acid reflux, and peptic ulcer disease. It helps alleviate symptoms like heartburn, stomach pain, irritation, acid reflux, indigestion, nausea, and vomiting. It is also used in conditions such as Zollinger-Ellison syndrome, which involves overproduction of acid due to a pancreatic tumor, and to manage ulcers associated with Crohn's disease.

How does RABICIP D CAPSULE work?

RABICIP D CAPSULE contains two active ingredients: Rabeprazole and Domperidone. Rabeprazole is a proton pump inhibitor (PPI) that reduces stomach acid by blocking an enzyme (H+/K+ ATPase, or gastric proton pump) responsible for acid secretion in the stomach wall. Domperidone is a prokinetic agent that increases the movement of the upper gastrointestinal tract, helping food move more easily through the stomach and preventing acid from flowing back into the food pipe. It also blocks the brain's vomiting-inducing center (chemoreceptor trigger zone-CTZ) to relieve nausea and vomiting.

What is the usual dosage for RABICIP D CAPSULE?

The usual dosage is one capsule once daily, taken preferably one hour before a meal, usually in the morning. The capsule should be swallowed whole with a glass of water and not crushed or chewed. The exact dose and duration of treatment will be determined by your doctor based on your condition and response to the medication.

What are the possible side effects of RABICIP D CAPSULE?

Common side effects can include headache, diarrhea, nausea, abdominal pain, vomiting, dizziness, dry mouth, and flatulence. Other possible side effects may include joint pain, flu-like symptoms, weakness, nasal congestion, back pain, skin rash, muscle pain, and difficulty sleeping. If you experience severe side effects like rash, swelling, difficulty breathing, or persistent problems, contact your doctor immediately.

Is RABICIP D CAPSULE safe during pregnancy or breastfeeding?

While RABICIP D CAPSULE is generally considered safe during pregnancy or breastfeeding, it is crucial to inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before starting treatment. Your doctor will weigh the potential benefits against any potential risks to the baby. Domperidone, one of the components, passes into breast milk.

Can RABICIP D CAPSULE be taken with other medications?

RABICIP D CAPSULE can interact with certain medications. It is important to inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential interactions. Specific medications that may interact include blood thinners (e.g., warfarin, clopidogrel), antifungals (e.g., ketoconazole, fluconazole), anti-HIV drugs (e.g., atazanavir), certain antibiotics (e.g., clarithromycin, erythromycin), iron supplements, and anti-cancer medications (e.g., methotrexate). It is also contraindicated with QT-prolonging drugs and potent CYP3A4 inhibitors.

What precautions should be taken while taking RABICIP D CAPSULE?

Avoid consuming alcohol and smoking, as these can exacerbate side effects and decrease the medicine's efficiency. You should also avoid caffeine-containing beverages, spicy, deep-fried, processed, and acidic foods. Inform your doctor if you have liver or kidney problems, heart conditions, stomach or intestinal cancer, a prolactin-releasing pituitary tumor, or a history of allergies to the medicine's components. Prolonged use may lead to deficiencies in Vitamin B12, calcium, magnesium, and Vitamin D, and may increase the risk of bone fractures. RABICIP D CAPSULE is generally not recommended for children under 5 or 16 years of age, depending on the source. This medicine may cause dizziness or drowsiness, so avoid activities requiring mental focus until you know how it affects you.

What happens if a dose of RABICIP D CAPSULE is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should RABICIP D CAPSULE be stored?

RABICIP D CAPSULE should be stored at room temperature, below 25°C or 30°C, in a cool and dry place, away from moisture and heat. Keep the medicine out of reach of children and pets. Do not use the medicine if it has passed its expiry date.