PRESSCLAV 228.5MG DRY SYRUP by VERITAZ HEALTHCARE

Name

Brand Name: PRESSCLAV 228.5MG DRY SYRUP

Composition

Each 5 ml of reconstituted syrup contains:

• Amoxicillin: 200 mg
• Clavulanic Acid: 28.5 mg

Amoxicillin is a penicillin-type antibiotic that works by inhibiting the formation of bacterial cell walls, leading to bacterial death. Clavulanic acid, a beta-lactamase inhibitor, enhances the effect of amoxicillin by preventing bacteria from inactivating it with beta-lactamase enzymes.

Uses

PRESSCLAV 228.5MG DRY SYRUP is a broad-spectrum antibiotic primarily used to treat various bacterial infections in children.

• Respiratory tract infections: Including bronchitis, pneumonia, tonsillitis, pharyngitis, sinusitis, and middle ear infections.
• Urinary tract infections (UTIs).
• Skin and soft tissue infections.
• Dental infections.
• Bone and joint infections.
• It may also be used in the treatment of resistant tuberculosis.

Dosage and Administration

The dose should be prescribed by a doctor, varying based on the infection's severity, type, and the child's weight and age.

• Administer orally with or without food, though taking it with food can enhance absorption and reduce stomach upset.
• The dry syrup needs to be reconstituted with sterile water according to package instructions before use.
• Shake the bottle well before each use.
• The prepared suspension should be stored in the refrigerator and used within 7 days; any leftover should be discarded.

Side Effects

Common side effects may include:

• Diarrhoea
• Nausea
• Vomiting
• Abdominal pain
• Skin rash, itching, and hives
• Headache
• Mucocutaneous candidiasis (a fungal infection)

If symptoms persist or worsen, medical attention should be sought.

Precautions

• Allergies: Do not administer if the child has a known hypersensitivity to penicillins, cephalosporins, or beta-lactamase inhibitors.
• Liver Disease: Use with caution in children with mild to moderate liver impairment; not recommended for severe liver diseases or if there's a history of amoxicillin-clavulanate-associated jaundice/hepatic dysfunction.
• Kidney Impairment: Dosage adjustment is necessary for children with impaired kidney function under medical supervision.
• Mononucleosis: May cause an erythematous skin rash in children with mononucleosis.
• Phenylketonuria: Contains aspartame (a source of phenylalanine), so use with caution in children diagnosed with phenylketonuria.
• Drug Interactions: Can interact with probenecid, oral anticoagulants (like warfarin), oral contraceptives, and methotrexate, potentially increasing toxicity or reducing effectiveness.

Storage

• Store the dry powder in a cool, dry place, below 30ºC, and away from direct sunlight.
• Keep out of reach and sight of children.
• Once reconstituted, the suspension should be kept in the refrigerator and used within 7 days.

PRESSCLAV 228.5MG DRY SYRUP: Frequently Asked Questions

PRESSCLAV 228.5MG DRY SYRUP, manufactured by VERITAZ HEALTHCARE, is an antibiotic commonly prescribed for children to treat various bacterial infections. This medicine combines Amoxycillin and Clavulanic acid to effectively combat a broad spectrum of bacteria.

Here are some frequently asked questions about PRESSCLAV 228.5MG DRY SYRUP:

What is PRESSCLAV 228.5MG DRY SYRUP used for?

PRESSCLAV 228.5MG DRY SYRUP is primarily used to treat bacterial infections in children. This includes respiratory tract infections (such as bronchitis, pneumonia, tonsillitis, pharyngitis, and sinusitis), ear infections, urinary tract infections, skin and soft tissue infections, dental infections, and bone and joint infections.

How does PRESSCLAV 228.5MG DRY SYRUP work?

This medicine contains two active ingredients: Amoxycillin and Clavulanic acid. Amoxycillin is a penicillin-type antibiotic that works by preventing the formation of the bacterial cell wall, which is essential for bacteria to survive, leading to their death. Clavulanic acid, on the other hand, is a beta-lactamase inhibitor. It blocks certain enzymes produced by bacteria that can destroy Amoxycillin, thereby enhancing Amoxycillin's effectiveness against resistant bacterial strains.

What is the usual dosage for PRESSCLAV 228.5MG DRY SYRUP?

The dosage of PRESSCLAV 228.5MG DRY SYRUP is determined by a doctor based on the severity and type of infection, as well as the child's body weight and age. It is typically given two to three times a day. The dry syrup needs to be mixed with sterile water according to the instructions on the package before administration. Shake the bottle well before each use. It is often recommended to give this medicine with food to improve absorption and reduce the risk of stomach upset.

What are the possible side effects of PRESSCLAV 228.5MG DRY SYRUP?

Common side effects may include indigestion, diarrhoea, nausea, vomiting, abdominal pain, skin rash, itching, hives, headache, and mucocutaneous candidiasis (a fungal infection). These side effects are usually temporary and tend to resolve on their own. However, if they persist or worsen, it is important to consult a doctor.

Is PRESSCLAV 228.5MG DRY SYRUP safe during pregnancy or breastfeeding?

PRESSCLAV 228.5MG DRY SYRUP is intended for use in children. For adults, if a similar medication containing amoxicillin and clavulanic acid is prescribed, caution is generally advised during pregnancy and breastfeeding. Some sources indicate that it is generally considered safe for use during pregnancy and breastfeeding if prescribed by a doctor, with animal studies showing low or no adverse effects. However, other sources advise using it with caution in pregnant and breastfeeding women and only when considered necessary, as it is a pediatric medicine. It is crucial for pregnant or breastfeeding individuals to consult their doctor.

Can PRESSCLAV 228.5MG DRY SYRUP be taken with other medications?

PRESSCLAV 228.5MG DRY SYRUP can interact with certain medications. For instance, concomitant use with blood thinners like warfarin can increase the risk of bleeding. It may also decrease the effectiveness of oral contraceptives and increase the toxicity risk of methotrexate. Always inform your doctor about all other medicines, supplements, or herbal products your child is currently taking to avoid potential interactions.

What precautions should be taken with PRESSCLAV 228.5MG DRY SYRUP?

Do not administer PRESSCLAV 228.5MG DRY SYRUP if your child is allergic to amoxicillin, clavulanic acid, penicillin, or any other beta-lactam antibiotics. Caution is advised for children with a history of liver or kidney problems. It is also important to complete the full course of treatment, even if symptoms improve, to prevent the infection from recurring and to avoid the development of antibiotic resistance. This medicine is only effective against bacterial infections and will not work for viral infections like the common cold or flu.

What happens if a dose is missed?

If a dose of PRESSCLAV 228.5MG DRY SYRUP is missed, give it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed one.

How should PRESSCLAV 228.5MG DRY SYRUP be stored?

Store the dry syrup in a cool and dry place, away from direct sunlight, at temperatures between 10ºC and 25ºC or below 30ºC. After preparation, the reconstituted suspension should be kept in the refrigerator and used within 7 days. Any leftover medicine after this period should be discarded. Keep the medicine out of reach and sight of children.