Mesalo Od Tablet (10 Tab)

MESALO OD TABLET (10 TAB) by CIPLA LTD.

MESALO OD TABLET is an anti-inflammatory medicine primarily used for the management of inflammatory bowel diseases.

• Name:

  • Brand Name: Mesalo OD Tablet
  • Common Name: Mesalazine (also known as Mesalamine)

• Composition:

  • Each MESALO OD TABLET contains Mesalazine 1200mg as its active ingredient.

• Uses:

  • MESALO OD TABLET is prescribed to treat and prevent mild to moderate ulcerative colitis, a chronic inflammatory bowel disease affecting the colon.
  • It is also used for the management of Crohn's disease, another inflammatory bowel disorder that can affect any part of the digestive tract.
  • The medicine helps reduce inflammation, alleviate symptoms such as diarrhea, rectal bleeding, and abdominal pain, and can help maintain remission to prevent flare-ups.

• Dosage and Administration:

  • MESALO OD TABLET should be taken as prescribed by your doctor.
  • It is generally recommended to take the tablet once daily, preferably after meals, but some sources suggest it can be taken either before or after food.
  • Do not crush, chew, or break the tablet; swallow it whole with water.
  • The typical dosage for induction of remission in active, mild to moderate ulcerative colitis is 2.4g to 4.8g once daily for adults.
  • Dosage may vary based on the severity of the condition and individual response.

• Side Effects:

  • Common side effects include nausea, diarrhea, stomach pain, headache, vomiting, indigestion, bloating, and flatulence.
  • Serious side effects, though rare, can include severe skin reactions (like Stevens-Johnson syndrome), kidney problems, liver irritation, heart inflammation, or severe stomach pain with bloody stools. Seek immediate medical attention if such severe symptoms occur.

• Precautions:

  • Do not take MESALO OD TABLET if you are allergic to Mesalazine, aspirin, salicylates, or any of its ingredients.
  • Caution is advised in patients with kidney or liver impairment; it is not recommended for severe kidney disease.
  • Inform your doctor if you have lung diseases like asthma or have experienced severe skin rashes.
  • Pregnant or breastfeeding women should consult their doctor before use.
  • Avoid alcohol consumption as it may worsen stomach irritation and liver toxicity.
  • Regular monitoring of kidney, liver, and blood functions is recommended during treatment.

• Storage:

  • Store MESALO OD TABLET in a cool and dry place, protected from direct sunlight and moisture.
  • Keep it out of reach of children.
  • Store at temperatures between 10ºC to 25ºC or below 30ºC.

Here are some frequently asked questions about MESALO OD TABLET, along with concise answers:

What is Mesalo OD Tablet used for?

Mesalo OD Tablet is primarily used to manage inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. It helps to reduce inflammation in the intestines, thereby alleviating symptoms like diarrhea, bleeding, and stomach pain, and can also help prevent flare-ups and maintain remission.

How does Mesalo OD Tablet work?

Mesalo OD Tablet contains mesalamine (also known as mesalazine), which works by reducing inflammation in the colon lining. It achieves this by blocking certain pathways (cyclooxygenase and lipoxygenase) that produce inflammatory mediators like prostaglandins and leukotrienes. Additionally, it acts as a potent antioxidant by scavenging free radicals and may modulate immune system activity in the gut.

What is the usual dosage of Mesalo OD Tablet?

The dosage of Mesalo OD Tablet is determined by your doctor and can vary based on individual factors, such as the severity of your condition and your response to the medicine. For adults and elderly patients, a maximum of 4.8g per day is recommended. It is crucial to follow your doctor's instructions regarding the dose and duration of treatment. The tablet should be swallowed whole with a glass of water, without crushing, chewing, or breaking it, and is often recommended to be taken with food.

What are the possible side effects of Mesalo OD Tablet?

Most side effects are generally mild and temporary, resolving as your body adjusts to the medication. Common side effects include stomach pain, headache, nausea, diarrhea, vomiting, itching, and flatulence. If these symptoms persist, worsen, or cause concern, you should consult your doctor. Rarely, more severe side effects like allergic reactions (swelling of face, tongue, throat, or lips, unusual bleeding, rash, fever), or issues affecting kidney or liver function, may occur, requiring immediate medical attention.

Is Mesalo OD Tablet safe during pregnancy or breastfeeding?

Mesalo OD Tablet should not generally be administered during pregnancy, and caution is advised. While some sources state it may be safe or have mild effects during pregnancy and breastfeeding, others suggest it is probably unsafe or requires extreme caution and a doctor's consultation to weigh benefits against risks. If prescribed during breastfeeding, monitor the infant for symptoms like diarrhea.

Can Mesalo OD Tablet be taken with other medications?

Mesalo OD Tablet can interact with certain medications. It is important to inform your doctor about all medicines, supplements, and herbal preparations you are taking. Specific interactions include:

• Medicines for constipation (e.g., lactulose): May lower stool pH and prevent mesalazine release.
• NSAIDs (e.g., ibuprofen, aspirin, diclofenac): May potentially worsen kidney function.
• Immunosuppressants (e.g., azathioprine, mercaptopurine, thioguanine): May increase the risk of renal reactions or need caution.
• Blood thinners (e.g., warfarin): May decrease the effect of warfarin.

What precautions should be taken while using Mesalo OD Tablet?

Inform your doctor if you have kidney or liver problems, as the medicine should be used with caution, and dose adjustments or monitoring may be needed. Patients with a history of peptic ulcers or gastrointestinal bleeding should also assess risks and benefits. Do not take Mesalo OD Tablet if you are allergic to mesalamine, salicylates (like aspirin), or any other ingredients. It is not recommended for children under 6 years old. Avoid or limit alcohol consumption as it may increase stomach irritation and liver toxicity. Regular kidney and liver function tests are recommended during long-term use.

What happens if a dose is missed?

If you forget to take a dose, take it as soon as you remember. However, if your next dose is due soon, skip the missed one and continue with your regular schedule. Do not double the dose to make up for a missed one.

How should Mesalo OD Tablet be stored?

Mesalo OD Tablet should be stored at room temperature, not exceeding 30°C. Protect the medicine from light and moisture, and keep it in its original tight container. Ensure it is kept out of the reach of children and pets, and always check the expiry date before use.