Salazar Tablet (10 Tab)

SALAZAR TABLET (10 TAB) by ZYDUS HEALTHCARE LIMITED

SALAZAR TABLET is a medication manufactured by Zydus Healthcare Limited, primarily used to manage various inflammatory conditions.

• Name:

  • Brand Name: Salazar Tablet
  • Common Name: Sulfasalazine Tablets

• Composition:

  • Active Ingredient: Sulfasalazine (500mg)

• Uses: SALAZAR TABLET is a Disease Modifying Anti-Rheumatoid Drug (DMARD) that works by suppressing the overactivity of the immune system and blocking chemical messengers that cause inflammation. It is prescribed for:

  • Inflammatory Bowel Diseases: Ulcerative colitis and Crohn's disease, to reduce inflammation in the digestive tract and manage symptoms like diarrhea, stomach pain, and fatigue. It helps maintain remission and prevent flare-ups.
  • Inflammatory Joint Conditions: Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis. It helps reduce joint pain, swelling, and stiffness, and can slow the progression of joint damage.
  • Skin Conditions: Psoriasis.

• Dosage and Administration:

  • Take SALAZAR TABLET as directed by your doctor, regularly and at the same time each day to maximize its benefits.
  • It can be taken with or without food, though taking it with food may help reduce gastrointestinal upset.
  • Swallow the tablet whole with a glass of water; do not crush, break, or chew it.
  • Drink plenty of fluids, especially water, while on this medication to help prevent kidney issues, including kidney stones.
  • It may take 6-8 weeks for the medicine to show its full effects.
  • Do not stop taking the medication suddenly without consulting your doctor, even if you feel better.

• Side Effects:

  • Common Side Effects: Nausea, headache, vomiting, stomach upset, indigestion, diarrhea, loss of appetite, fatigue, and weight loss.
  • Your skin, urine, saliva, and tears may turn orange or yellow, which is a normal and harmless effect of this medicine. It may also make your skin more sensitive to sunlight.
  • Serious Side Effects (Consult your doctor if experienced): Persistent sore throat, fever, unexplained bruising, ringing in the ears (tinnitus), allergic reactions, liver problems, blood disorders, lung issues, or Stevens-Johnson syndrome. Salazar Tablet can also temporarily lower sperm count in men, which is usually reversible upon stopping the medication.

• Precautions:

  • Do not take SALAZAR TABLET if you are allergic to sulfasalazine, sulfa drugs, or aspirin.
  • Inform your doctor if you have kidney, liver, or heart problems, asthma, blood disorders (e.g., anemia, porphyria), or intestinal or urinary obstruction.
  • Regular blood tests are necessary to monitor liver function, kidney function, and blood component levels.
  • Avoid consuming alcohol while taking this medicine or discuss it with your doctor.
  • If you are pregnant or breastfeeding, consult your doctor. While generally considered safe during pregnancy with medical supervision (and possibly folic acid supplementation), it is generally advised against during breastfeeding as it can pass into milk and potentially affect infants.
  • Inform your doctor about all other medications you are taking, especially blood thinners (like warfarin), digoxin, iron supplements, anti-diabetic medications, certain antibiotics, immune system affecting drugs (like azathioprine, mercaptopurine), methotrexate, or isoniazid, as interactions can occur.
  • This medicine is not recommended for children under 2 years of age.
  • SALAZAR TABLET may cause dizziness or fatigue; avoid driving or operating heavy machinery if you experience these effects.

• Storage:

  • Store SALAZAR TABLET in a cool and dry place, protected from direct sunlight, moisture, and heat.
  • Keep it out of the sight and reach of children and pets.
  • Do not freeze the medicine.
  • Discard any expired or damaged medicines properly.

SALAZAR TABLET (10 TAB) by ZYDUS HEALTHCARE LIMITED

What is Salazar Tablet used for?

Salazar Tablet is primarily used to treat inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. It is also prescribed for various arthritic conditions including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis, especially when they do not respond to other treatments.

How does Salazar Tablet work?

Salazar Tablet, containing sulfasalazine, is a Disease-Modifying Anti-Rheumatoid Drug (DMARD) and an anti-inflammatory agent. It functions by suppressing the overactivity of the immune system in autoimmune conditions and by blocking chemical messengers that contribute to inflammation. The medicine is a prodrug that is broken down by intestinal bacteria into two active components: sulfapyridine and 5-aminosalicylic acid (5-ASA). Sulfapyridine provides systemic immunomodulatory effects, while 5-ASA primarily offers local anti-inflammatory effects in the gut by inhibiting the production of prostaglandins, which are chemicals responsible for pain and inflammation.

What is the usual dosage for Salazar Tablet?

The dosage of Salazar Tablet should be strictly followed as directed by your doctor. It is generally recommended to take this medicine with food to help reduce stomach upset. For adults with ulcerative colitis, a common starting dose might be 500 to 1000 milligrams every 6 to 8 hours daily, not exceeding 4000 mg per day. For children aged 6 years and older, the dose is determined by body weight, typically 40 to 60 milligrams per kilogram of body weight per day, divided into 3 to 6 doses. It may take 6 to 8 weeks to observe its full effects.

What are the possible side effects of Salazar Tablet?

Common side effects can include weight loss, loss of appetite, nausea, vomiting, stomach upset, diarrhea, headache, and gastrointestinal discomfort. Salazar Tablet may also cause your skin, urine, saliva, and tears to turn an orange or yellow color, which is usually harmless. In men, it can lead to a low sperm count, but this is typically reversible. More serious, though less common, side effects include allergic reactions, liver problems, blood disorders (like hemolytic anemia, especially in individuals with G6PD deficiency), and lung issues.

Is Salazar Tablet safe during pregnancy or breastfeeding?

During pregnancy, Salazar Tablet is generally considered safe if prescribed by a doctor, but it's crucial to consult your doctor if you are pregnant or planning a pregnancy. However, some sources suggest it should be taken only under medical advice due to potentially severe side effects. Salazar Tablet is generally not recommended during breastfeeding unless absolutely necessary, as it can pass into breast milk and may harm the infant, potentially causing diarrhea, blood in the stools, jaundice, or brain problems in infants under 2 years of age. Always consult your doctor before using this medicine while breastfeeding.

Can Salazar Tablet be taken with other medications?

Salazar Tablet can interact with certain medications. It is known to potentially interact with aminolevulinic acid, cyclosporine, digoxin, and warfarin. While specific interaction information can be limited for all drugs, it is essential to inform your doctor about all other medications, including over-the-counter drugs, supplements, and herbal remedies, you are currently taking to avoid potential adverse interactions.

What precautions should be taken while taking Salazar Tablet?

Do not take Salazar Tablet if you are allergic to sulfasalazine, other sulfa drugs, or aspirin. It is not suitable for individuals with conditions such as anemia, asthma, liver or kidney problems, porphyria, intestinal or urinary obstruction, or severe blood disorders. You should drink plenty of fluids while on this medication to help prevent the formation of kidney stones. Avoid consuming alcohol during treatment. Regular blood tests will be needed to monitor your liver function, kidney function, and blood components. Do not stop taking the medication suddenly without consulting your doctor. It is not recommended for children younger than 2 years of age.

What happens if a dose of Salazar Tablet is missed?

If you miss a dose of Salazar Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should Salazar Tablet be stored?

Salazar Tablet should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat, typically below 30°C. Ensure it is kept out of sight and reach of children and pets. It should not be frozen.