Storvas Ez 10

Storvas EZ 10 Tablet

Storvas EZ 10 Tablet, manufactured by Sun Pharmaceutical Industries Ltd., is a combination medication primarily used to manage high cholesterol levels.

• Composition: Each tablet contains Atorvastatin 10 mg and Ezetimibe 10 mg. Atorvastatin belongs to the statin class of medicines, working by inhibiting an enzyme crucial for cholesterol production in the liver. Ezetimibe is a cholesterol absorption inhibitor that prevents the absorption of cholesterol from the intestines. This dual action provides a more comprehensive approach to reducing cholesterol in the body.

• Uses: Storvas EZ 10 Tablet is prescribed for:

  • Treating high cholesterol (hypercholesterolemia/dyslipidemia) by reducing "bad" cholesterol (LDL) and triglycerides, while increasing "good" cholesterol (HDL).
  • Reducing the risk of heart attack and stroke.
  • Managing homozygous familial hypercholesterolemia.
  • Treating mixed dyslipidemia and hypertriglyceridemia.
  • Lowering the need for coronary revascularization procedures.

• Dosage and Administration: The typical dosage is one tablet once daily, or as directed by a doctor. It can be taken with or without food, but it is recommended to take it at a fixed time each day to help remember. The tablet should be swallowed whole and not chewed, crushed, or broken. The dose and duration of treatment depend on the condition being treated and the patient's response.

• Side Effects:

  • Common: Nausea, muscle pain (myalgia), increased transaminase levels in blood, upper respiratory tract infection, headache, diarrhea, constipation, stomach pain, and joint pain (arthralgia).
  • Serious: Severe muscle pain, signs of liver damage (such as yellowing of the skin or eyes, dark urine, loss of hunger, sick feeling), unexplained bleeding or bruising, severe allergic reactions, or shortness of breath. If these or other serious symptoms occur, medical attention should be sought immediately.

• Precautions:

  • Alcohol: Avoid or limit alcohol consumption due to an increased risk of liver damage.
  • Pregnancy and Breastfeeding: Highly unsafe during pregnancy and not recommended during breastfeeding.
  • Medical Conditions: Inform your doctor if you have kidney disease, thyroid problems, a history of muscle disorders (including rhabdomyolysis), liver issues, or diabetes. Regular monitoring of liver function and blood sugar levels may be advised.
  • Interactions: Inform your doctor about all other medicines, supplements, or herbal products being taken, as they may interact with Storvas EZ 10. Avoid grapefruit juice, as it can increase the risk of side effects.
  • Children and Elderly: Generally not recommended for children below 18 years. Caution is advised in elderly patients as they may be more susceptible to side effects.
  • Driving: May decrease alertness or cause dizziness in some individuals. Caution is advised when driving or operating machinery if these effects occur.

• Storage: Store below 30°C in a cool and dry place, away from moisture and direct sunlight. Keep out of sight and reach of children and pets.

STORVAS EZ 10 is a medication manufactured by SUN PHARMACEUTICAL IND.LTD. It is a combination of two active ingredients: Atorvastatin (10 mg) and Ezetimibe (10 mg). This medicine is primarily used to manage high cholesterol levels and reduce the risk of heart attack and stroke.

Here are some frequently asked questions about STORVAS EZ 10:

What is STORVAS EZ 10 used for?

STORVAS EZ 10 is used to treat high cholesterol, also known as hypercholesterolemia. It helps to lower "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL) in the blood. By managing cholesterol levels, it helps reduce the risk of heart disease, heart attack, and stroke. It is also used in cases of primary hypercholesterolemia, familial hypercholesterolemia, and to reduce the need for coronary revascularization procedures.

How does STORVAS EZ 10 work?

STORVAS EZ 10 combines two medicines: Atorvastatin and Ezetimibe, which work together to reduce cholesterol.

• Atorvastatin belongs to the statin class of medicines. It works by blocking an enzyme called HMG-CoA reductase in the liver, which plays a crucial role in the body's cholesterol production. This reduces overall cholesterol levels and can slightly increase HDL ("good") cholesterol.
• Ezetimibe inhibits the absorption of cholesterol from the small intestine by selectively blocking a protein called Niemann-Pick C1-Like 1 (NPC1L1). This dual mechanism helps to comprehensively lower cholesterol by targeting both its production and absorption.

What is the usual dosage of STORVAS EZ 10?

The usual starting adult dose for hypercholesterolemia is one tablet containing atorvastatin 10 mg and ezetimibe 10 mg, once daily. You should take your daily dose exactly as prescribed by your doctor. The dosage can vary depending on individual factors like the severity of your condition and how you respond to the medication. It can be taken with or without food, preferably at the same time each day to help you remember. Do not crush or chew the tablet; swallow it whole with a glass of water.

What are the possible side effects of STORVAS EZ 10?

Common side effects of STORVAS EZ 10 may include nasopharyngitis (inflammation of the nasal passages and throat), muscle pain (myalgia), upper respiratory tract infection, joint pain (arthralgia), and diarrhea. Other reported side effects include nausea, stomach pain, headache, constipation, fatigue, and increased liver enzymes or blood glucose levels. Most side effects are temporary and generally resolve on their own. However, if you experience any serious side effects such as severe muscle pain, signs of liver damage (yellowing of skin or eyes, dark urine), unexplained bleeding or bruising, or severe allergic reactions, consult your doctor immediately.

Is STORVAS EZ 10 safe during pregnancy or breastfeeding?

STORVAS EZ 10 is generally not recommended for use during pregnancy and is considered highly unsafe. Women of childbearing age should use effective contraception while taking this medication. It is also not advised during breastfeeding, as it may pass into breast milk and could potentially harm a nursing infant. Consult your doctor for alternative lipid-lowering agents if you are pregnant or breastfeeding.

Can STORVAS EZ 10 be taken with other medications?

STORVAS EZ 10 can interact with other medications.

• CYP3A4 Inhibitors (e.g., cyclosporine, erythromycin, protease inhibitors) can increase levels of atorvastatin in your bloodstream, potentially raising the risk of muscle-related side effects.
• Bile Acid Sequestrants (e.g., cholestyramine) can decrease ezetimibe levels. If taking these, it's best to take STORVAS EZ 10 either two hours before or four hours after to ensure effective absorption.
• Other medications like fibrates, niacin, certain antifungals, anti-HIV medicines, anticoagulants (e.g., warfarin), and antacids may also interact. It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

What precautions should be taken with STORVAS EZ 10?

Several precautions should be taken:

• Liver Disease: STORVAS EZ 10 is contraindicated in patients with active liver disease or persistent unexplained increases in liver enzymes. Regular monitoring of liver function tests is recommended.
• Alcohol Consumption: Exercise caution with regular alcohol consumption, as it can increase the risk of liver damage.
• Kidney Disease: Use with caution in patients with severe kidney issues.
• Muscle Disorders: Inform your doctor if you have a history of muscle disorders due to the risk of muscle pain, weakness, or rhabdomyolysis.
• Grapefruit Juice: Avoid consuming grapefruit juice as it may increase the risk of side effects.
• Diabetes: It may cause a slight increase in blood sugar levels, so monitoring is advised for diabetic patients.
• Children and Elderly: Not recommended for children under 10 years of age. Older patients may be more susceptible to side effects and should take it under medical supervision.

What happens if a dose is missed?

If you forget to take a dose of STORVAS EZ 10, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should STORVAS EZ 10 be stored?

STORVAS EZ 10 should be stored at room temperature, typically below 30°C (86°F) or between 20-25°C. Keep it in a cool and dry place, away from moisture, heat, and direct sunlight. Keep the medication out of sight and reach of children and pets.