Numlo D Tablet

NUMLO D TABLET

NUMLO D TABLET, manufactured by Emcure Pharmaceuticals Ltd., is a combination medication primarily used for the management of hypertension, commonly known as high blood pressure.

Composition NUMLO D TABLET contains a combination of two active ingredients:

• S-Amlodipine (Levamlodipine): This is a calcium channel blocker that works by relaxing and widening blood vessels, allowing blood to flow more easily and improving the heart's efficiency in pumping blood throughout the body.
• Hydrochlorothiazide: This is a diuretic (water pill) that helps the body eliminate excess water and certain electrolytes, such as sodium, through urine, thereby reducing blood volume and pressure.

NUMLO D TABLET is available in different strengths, such as S-Amlodipine 2.5mg or 5mg combined with Hydrochlorothiazide 12.5mg.

Uses NUMLO D TABLET is prescribed for:

• Treatment of hypertension (high blood pressure).
• Reducing the risk of associated cardiovascular complications such as heart attack, stroke, and angina (chest pain).
• Management of fluid retention (edema) associated with heart failure.

Dosage and Administration The tablet should be taken orally, usually once daily. It is advisable to take it at the same time each day to maintain consistent medicine levels in the blood, preferably during the day to minimize nighttime urination. The tablet should be swallowed whole with a glass of water and not chewed, crushed, or broken. Do not discontinue the medication abruptly without consulting a doctor, as this can worsen symptoms.

Side Effects Common side effects of NUMLO D TABLET may include:

• Headache
• Edema (swelling), particularly of the ankles
• Fatigue, tiredness
• Nausea, abdominal pain
• Sleepiness, dizziness, flushing (sense of heat in the face, ears, neck, and trunk)
• Decreased potassium levels in the blood
• Increased blood uric acid
• Altered blood lipid levels
• Changes in taste, tingling sensation in limbs, ringing in the ears

Serious side effects, though less common, can include severe dizziness, very low blood pressure, and irregular heartbeat (especially in cases of overdose). Report persistent or bothersome side effects to a healthcare professional.

Precautions

• Medical Conditions: Use with caution in patients with liver, kidney, or severe heart conditions (such as aortic stenosis or coronary artery diseases), diabetes mellitus, hypokalemia, gout, or low levels of sodium or magnesium in the blood.
• Alcohol and Grapefruit: Avoid consuming alcohol as it can enhance the effects of low blood pressure and cause dizziness. Also, avoid grapefruit or grapefruit juice, as it can significantly lower blood pressure.
• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as information on its safety during these periods is limited.
• Driving: Drowsiness and dizziness may occur, so avoid activities requiring attention, such as driving or operating machinery, if you experience these effects.
• Interactions: Inform your healthcare provider about all other medicines you are taking, as interactions may occur.
• Monitoring: Regular monitoring of blood pressure, kidney function, electrolyte levels, and blood sugar levels is essential during treatment.

Storage Store the medicine below 25°C. Keep it away from direct sunlight and moisture. Ensure it is out of the sight and reach of children.

What is NUMLO D Tablet used for?

NUMLO D Tablet is a combination medication primarily prescribed for the treatment of hypertension, also known as high blood pressure. It helps in managing high blood pressure and reducing the associated risks of heart attack, stroke, and angina (chest pain).

How does NUMLO D Tablet work?

NUMLO D Tablet contains two active ingredients: S-Amlodipine and Hydrochlorothiazide. S-Amlodipine is a calcium channel blocker that works by relaxing and widening blood vessels, which improves blood flow. Hydrochlorothiazide is a diuretic ("water pill") that helps the body eliminate excess water and certain electrolytes through urine, thereby reducing blood volume and blood pressure.

What is the usual dosage for NUMLO D Tablet?

NUMLO D Tablet is typically taken once daily, with or without food, at the same time each day to maintain consistent medicine levels in the blood. The specific dosage will be determined by your doctor based on your age, weight, and health condition.

What are the possible side effects of NUMLO D Tablet?

Common side effects may include headache, swelling (edema) in the ankles, fatigue, nausea, abdominal pain, sleepiness, dizziness, and flushing (redness and warmth of the skin). Most of these are usually mild and temporary. If side effects persist or worsen, it's advisable to consult your doctor.

Is NUMLO D Tablet safe during pregnancy or breastfeeding?

NUMLO D Tablet is generally not recommended during pregnancy or breastfeeding. It should only be used if considered absolutely necessary by your doctor, who will weigh the potential benefits against the risks. There is a potential for fetal harm if used during pregnancy, particularly in the second and third trimesters. Consult your doctor immediately if you are pregnant, planning to become pregnant, or breastfeeding.

Can NUMLO D Tablet be taken with other medications?

Interactions with other medications are possible. It is crucial to inform your doctor about all other medicines, vitamins, nutritional supplements, and herbal products you are taking. Avoid consuming grapefruit or grapefruit juice, as it can significantly lower blood pressure. Certain medications for fungal infections (e.g., ketoconazole, itraconazole), HIV infections (e.g., ritonavir), bacterial infections (e.g., rifampicin, erythromycin, clarithromycin), muscle spasms (dantrolene), and elevated cholesterol levels (e.g., simvastatin) may interact with NUMLO D Tablet. Painkillers should also be avoided unless advised by your doctor.

What precautions should be taken while on NUMLO D Tablet?

Inform your doctor if you have liver or kidney disease, other heart problems (such as heart failure or severe aortic stenosis), diabetes, severe low blood pressure, dehydration, electrolyte imbalance, glaucoma, gout, lupus, gallstones, or a penicillin allergy. Regular monitoring of blood pressure, kidney function, electrolyte levels, and blood sugar levels is important during treatment. This medication may cause dizziness or drowsiness, so exercise caution when driving or performing activities that require concentration. Do not stop taking NUMLO D Tablet abruptly without consulting your doctor, as this can worsen your symptoms.

What happens if a dose of NUMLO D Tablet is missed?

If you miss a dose of NUMLO D Tablet, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. It is important to complete the full course of treatment as prescribed by your doctor.

How should NUMLO D Tablet be stored?

Store NUMLO D Tablet below 25°C. Keep it away from moisture and heat, and out of the sight and reach of children.