Nexovas Tc Tablet

NEXOVAS TC TABLET

NEXOVAS TC TABLET by Macleods Pharmaceuticals Pvt Ltd is a combination medication primarily used for the management of essential hypertension (high blood pressure) in adults. It is prescribed when blood pressure cannot be effectively controlled by a single medication. By effectively managing blood pressure, it helps reduce the risk of severe cardiovascular events such as strokes and heart attacks.

• Composition: Each tablet contains three active ingredients that work synergistically to lower blood pressure:

  • Telmisartan (40 mg): An angiotensin II receptor blocker (ARB) that works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, leading to their relaxation and widening.
  • Cilnidipine (10 mg): A calcium channel blocker that prevents calcium influx across L-type and N-type channels in the body's cells, relaxing blood vessels and improving blood flow.
  • Chlorthalidone (12.5 mg): A diuretic ("water pill") that increases the excretion of sodium, chloride, and water from the body through the kidneys, thereby reducing blood volume and lowering blood pressure.

• Uses:

  • Lowering high blood pressure (hypertension) in adults.
  • Reducing the risk of severe heart-related events like strokes and heart attacks.
  • Initial therapy for individuals likely to require multiple medications to achieve blood pressure targets.

• Dosage and Administration: The typical dosage is one tablet daily. It should be swallowed whole with a glass of water, without crushing or chewing, and preferably taken at the same time each day to maintain consistent blood levels. NEXOVAS TC TABLET can be taken with or without food, though some sources suggest taking it with food. Due to its diuretic component, it is advisable to avoid taking it within four hours of bedtime to prevent frequent urination. Do not stop the medication without consulting a doctor.

• Side Effects:

  • Common: Dizziness, headache, fatigue, nausea, back pain, diarrhea, hypotension (low blood pressure), ankle swelling, upset stomach, tiredness, and taste change.
  • Serious: Electrolyte imbalance (muscle weakness, twitching, numbness, confusion, slow or irregular heartbeat), severe dizziness, chest pain, difficulty breathing, irregular heartbeat, eye pain, sudden changes in vision, or signs of an allergic reaction (rash, swelling, difficulty swallowing).

• Precautions:

  • Pregnancy: Contraindicated; it can cause serious harm to the unborn baby, especially after the first three months.
  • Breastfeeding: Not recommended as it may pass into breast milk and harm the baby.
  • Alcohol: Avoid alcohol consumption as it can increase the risk of low blood pressure and exaggerate side effects.
  • Liver/Kidney Conditions: Use with caution in patients with liver or kidney problems; contraindicated in severe liver or kidney disease and anuria.
  • Driving and Using Machines: May cause dizziness or tiredness, so caution is advised.
  • Drug Interactions: Inform your doctor about all medications, including supplements and herbal products. It may interact with antidiabetic medicines, lithium compounds, NSAIDs, aliskiren, and certain other blood pressure medications.
  • Other Warnings: Not recommended for children under 18 years. Caution is advised in older patients. Regular monitoring of blood pressure, kidney function, electrolytes, and blood sugar levels is important.

• Storage: Store in a cool and dry place, ideally at room temperature below 30°C. Keep it away from direct heat and light, and out of reach of children.

NEXOVAS TC TABLET is a combination medicine used to treat hypertension (high blood pressure) in adults. It contains three active ingredients: Telmisartan, Cilnidipine, and Chlorthalidone, which work together to effectively lower blood pressure and reduce the risk of associated cardiovascular events like strokes and heart attacks.

Here are some frequently asked questions about NEXOVAS TC TABLET:

What is NEXOVAS TC TABLET used for?

NEXOVAS TC TABLET is primarily used to manage essential hypertension (high blood pressure not caused by any other underlying condition) in adults. It also helps to lower the risk of severe cardiovascular complications such as heart attacks and strokes.

How does NEXOVAS TC TABLET work?

This medicine combines three active ingredients:

• Telmisartan: An angiotensin II receptor blocker (ARB) that works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow. This allows blood vessels to relax and widen, reducing blood pressure.
• Cilnidipine: A calcium channel blocker that prevents calcium from entering the cells of the heart and blood vessels. This relaxes and widens blood vessels, improving blood flow and reducing the heart's workload.
• Chlorthalidone: A diuretic (water pill) that acts on the kidneys to increase the excretion of excess sodium, chloride, and water from the body through urine. This reduces blood volume and consequently lowers blood pressure. The combined action of these ingredients provides a comprehensive approach to blood pressure control.

What is the usual dosage of NEXOVAS TC TABLET?

The typical recommended dosage of NEXOVAS TC TABLET is one tablet daily, taken orally. It is usually prescribed to be taken at the same time each day to maintain a consistent level of medication in your bloodstream. Your doctor will determine the correct dosage and frequency based on your condition and response to the medicine.

What are the possible side effects of NEXOVAS TC TABLET?

Common side effects may include dizziness, headache, fatigue, nausea, back pain, diarrhea, and low blood pressure (hypotension). Other possible side effects include ankle swelling, upset stomach, and electrolyte imbalance. If any side effects persist or worsen, you should consult your doctor.

Is NEXOVAS TC TABLET safe during pregnancy or breastfeeding?

NEXOVAS TC TABLET is generally not recommended during pregnancy as it can harm the unborn baby, especially if used after the first three months of pregnancy. If you become pregnant while taking this medicine, stop immediately and consult your doctor. It is also not recommended for breastfeeding mothers as it may pass into breast milk and affect the baby's health.

Can NEXOVAS TC TABLET be taken with other medications?

NEXOVAS TC TABLET can interact with several other medications. For instance, antidiabetic medicines (like glimepiride, insulin, or metformin) may require dosage adjustments due to potential changes in blood glucose levels. Concomitant use with lithium compounds can increase the risk of lithium toxicity. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) like ibuprofen, naproxen, and diclofenac may decrease the antihypertensive effect and potentially increase the risk of kidney impairment. It is crucial to inform your doctor about all medicines, supplements, and herbal products you are taking to prevent potential interactions.

What precautions should be taken?

• Alcohol: Avoid or limit alcohol consumption while taking NEXOVAS TC TABLET as it can increase the risk of side effects like dizziness and low blood pressure.
• Driving & Operating Machinery: This medicine may cause dizziness or tiredness. Avoid driving or operating machinery until you know how it affects you.
• Liver/Kidney Conditions: Use with caution if you have liver or kidney problems. It is not recommended for severe liver or kidney disease.
• Electrolyte Imbalance: The diuretic component (Chlorthalidone) can lead to electrolyte imbalances; regular monitoring of electrolyte levels is advised.
• Grapefruit Juice: Avoid consuming grapefruit or grapefruit juice, as it may interact with the medication and increase its levels in the body.
• Do not stop suddenly: Do not stop taking the medicine without consulting your doctor, as abrupt discontinuation can lead to serious complications like a sudden increase in blood pressure, heart attack, or stroke.

What happens if a dose is missed?

If you miss a dose of NEXOVAS TC TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should it be stored?

Store NEXOVAS TC TABLET in a cool and dry place, ideally at room temperature below 30°C. Keep it away from direct heat, light, and moisture to maintain its strength. Always ensure the tablets are out of reach of children.