Xet Cr 25 Mg Tablet (10 Tab)

XET CR 25 MG TABLET is a medication manufactured by Zydus Healthcare Limited.

Name

• Brand Name: XET CR 25 Tablet
• Common Name: Paroxetine Controlled Release

Composition

• Active Ingredient: Paroxetine 25 mg

Uses

XET CR 25 Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant prescribed for various mental health conditions. It works by increasing serotonin levels in the brain, which helps regulate mood.

• Major Depressive Disorder: Treats persistent feelings of sadness and improves mood.
• Obsessive-Compulsive Disorder (OCD): Helps reduce intrusive thoughts and compulsive behaviors.
• Panic Disorder: Manages panic attacks and associated symptoms.
• Social Anxiety Disorder: Addresses abnormal fear in social situations.
• Post-Traumatic Stress Disorder (PTSD): Aids in alleviating symptoms related to traumatic events.
• Premenstrual Dysphoric Disorder (PMDD): Used to treat symptoms associated with this condition.
• Generalised Anxiety Disorder (GAD): Reduces excessive worry and fear.

Dosage and Administration

XET CR 25 Tablet should be taken as prescribed by a doctor. It is typically taken once daily, usually in the morning, with or without food, though taking it with food may reduce stomach upset. The tablet should be swallowed whole and not crushed, broken, or chewed. The dosage may be adjusted by the doctor based on the patient's condition and response to treatment. Do not stop taking the medicine abruptly, as this can lead to withdrawal symptoms. This medicine is not recommended for children below 18 years of age.

Side Effects

Common Side Effects:

• Nausea
• Fatigue, weakness
• Dry mouth
• Dizziness, tremors
• Insomnia (difficulty sleeping)
• Headache
• Loss of appetite
• Increased sweating
• Sexual disturbances (e.g., decreased libido, erectile dysfunction, delayed ejaculation)

Serious Side Effects:

• Sudden worsening of mood or suicidal thoughts
• Unusual bruising or bleeding
• Seizures or fits
• Signs of akathisia (restlessness)
• Symptoms of low sodium (tiredness, confusion, muscle pain)
• Allergic reactions (rash, swelling of face/tongue, difficulty breathing)
• Serotonin syndrome (fever, rigid muscles, mental changes, fast heartbeat)

Precautions

• Pregnancy and Breastfeeding: Not recommended during pregnancy as it may harm the fetus. Consult a doctor if breastfeeding.
• Alcohol: Avoid alcohol consumption as it may worsen side effects.
• Driving and Machinery: May cause dizziness, confusion, sleepiness, or blurred vision, so avoid driving or operating machinery.
• Medical Conditions: Inform your doctor if you have a history of epilepsy, diabetes, liver or kidney disease, heart problems, or glaucoma.
• Drug Interactions: Inform your doctor about all medications, herbal supplements, and vitamins you are taking. Avoid concomitant use with MAO inhibitors, Thioridazine, Selegiline, Linezolid, and Metoclopramide without medical advice due to potential for serious interactions like Serotonin Syndrome. Avoid grapefruit or grapefruit juice as it may interact with the medication.
• Children and Elderly: Not recommended for children under 18 years. Use with caution in elderly patients.

Storage

Store in a cool and dry place, away from direct sunlight, and out of the reach and sight of children. Store below 30°C.

What is XET CR 25 MG TABLET used for?

XET CR 25 MG TABLET, containing Paroxetine, is primarily used to treat various mental health conditions. These include major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), and generalized anxiety disorder.

How does XET CR 25 MG TABLET work?

XET CR 25 MG TABLET is a selective serotonin reuptake inhibitor (SSRI). It works by increasing the levels of serotonin, a natural chemical messenger in the brain that plays a crucial role in regulating mood, energy levels, and overall emotional well-being. By inhibiting the reuptake of serotonin by nerves, it helps to improve mood and alleviate symptoms of depression and anxiety.

What is the usual dosage of XET CR 25 MG TABLET?

The usual dosage is once daily, typically in the morning. It can be taken with or without food, though taking it with food may help reduce stomach upset. The tablet should be swallowed whole and not crushed, broken, or chewed. Your doctor will determine the appropriate dose and duration of treatment based on your medical condition and response. It may take several weeks to experience the full benefits.

What are the possible side effects of XET CR 25 MG TABLET?

Common side effects can include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty sleeping), constipation, and sexual side effects such as decreased libido, erectile dysfunction, and delayed ejaculation. More serious but less common side effects can include suicidal thoughts or actions, serotonin syndrome, and an increased risk of abnormal bleeding. If any side effects persist or worsen, or if you experience sudden mood changes or thoughts of harming yourself, it is important to contact your doctor immediately.

Is XET CR 25 MG TABLET safe during pregnancy or breastfeeding?

During Pregnancy: XET CR 25 MG TABLET is generally not recommended during pregnancy as it may cause harm to the fetus. Some studies suggest a small, possibly increased risk of cardiovascular abnormalities, especially with doses greater than 25 mg per day. Use in the last trimester may lead to short-term withdrawal symptoms or, rarely, breathing problems in the newborn, and a slightly increased risk of bleeding after delivery. You should discuss the risks and benefits with your doctor if you are pregnant or planning a pregnancy.

During Breastfeeding: XET CR 25 MG TABLET passes into breast milk in small amounts. While generally considered acceptable if the baby is healthy and monitored, caution is advised. It is important to watch your baby for signs such as unusual sleepiness, irritability, or not feeding as well as usual, and to consult your doctor or health visitor if you have any concerns.

Can XET CR 25 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all prescription and over-the-counter medicines, vitamins, herbal products, and other supplements you are taking. XET CR 25 MG TABLET should not be taken with Monoamine Oxidase Inhibitors (MAOIs) due to the risk of a serious condition called serotonin syndrome. Caution is also advised with medications like thioridazine, and those that affect bleeding, such as aspirin, NSAIDs (e.g., ibuprofen, naproxen), and blood thinners (e.g., warfarin).

What precautions should be taken while taking XET CR 25 MG TABLET?

Avoid consuming alcohol while taking this medicine as it can worsen symptoms and side effects like dizziness and drowsiness. Do not drive or operate heavy machinery if you experience dizziness, confusion, sleepiness, or blurred vision. XET CR 25 MG TABLET is generally not recommended for individuals under 18 years of age due to concerns regarding safety and effectiveness, and an increased risk of suicidal thoughts. Inform your doctor about any pre-existing medical conditions, including epilepsy, diabetes, liver or kidney disease, heart problems, glaucoma, bipolar disorder, or bleeding disorders. Do not stop taking the medication abruptly without consulting your doctor, as this can lead to unpleasant withdrawal symptoms.

What happens if a dose of XET CR 25 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should XET CR 25 MG TABLET be stored?

XET CR 25 MG TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach and sight of children and pets. The typical storage temperature is below 30°C (or between 20°C to 25°C).