Flutas 400 Mg Tablet

FLUTAS 400 MG TABLET

FLUTAS 400 MG Tablet, manufactured by Intas Pharmaceuticals Ltd., is an antifungal medication used to treat a wide range of fungal infections.

• Name:
  • Common Name: Fluconazole
  • Brand Name: FLUTAS 400 MG Tablet
• Composition:
  • The active ingredient is Fluconazole at a strength of 400 mg. Fluconazole works by inhibiting the growth of fungi, specifically by disrupting the synthesis of ergosterol, a crucial component of fungal cell membranes.
• Uses: FLUTAS 400 MG Tablet is prescribed for various fungal infections caused by Candida and other yeasts. These include:
  • Vaginal yeast infections (vaginal candidiasis).
  • Oral thrush (oropharyngeal candidiasis) and esophageal candidiasis.
  • Systemic fungal infections in areas like the mouth, throat, skin, lungs, liver, kidneys, and urinary tract.
  • Cryptococcal meningitis, a fungal infection affecting the brain and spinal cord.
  • Fungal skin infections such as athlete's foot, ringworm, and jock itch, as well as nail infections.
  • It can also be used to prevent candidiasis and coccidioidomycosis in patients with cancer or those who have undergone bone marrow transplantation.
• Dosage and Administration:
  • FLUTAS 400 MG Tablet should be taken as directed by a healthcare professional.
  • Swallow the tablet whole with a glass of water, with or without food.
  • The typical dosage is often once daily, but the dose and duration of treatment vary depending on the specific condition being treated.
  • It is crucial to complete the full course of treatment, even if symptoms improve, to ensure the infection is completely cured and to prevent recurrence or the development of drug-resistant infections.
  • Avoid taking antacids within 1-2 hours before or after taking this medication.
• Side Effects: Common side effects may include:
  • Headache.
  • Nausea and vomiting.
  • Abdominal or stomach pain.
  • Diarrhoea.
  • Skin rash.
  • Taste disturbances. Serious side effects can include severe skin rashes (e.g., blistering), dizziness, or signs of an allergic reaction (rash, swelling of the lips/face, difficulty breathing). Consult a doctor if any side effects persist, worsen, or if serious symptoms occur.
• Precautions:
  • Allergy: Do not use if allergic to fluconazole or any of its ingredients.
  • Pregnancy and Breastfeeding: FLUTAS 400 MG Tablet should be used with caution during pregnancy and breastfeeding, and only if clearly necessary, as there is evidence of risk to the developing baby. Consult your doctor.
  • Liver/Kidney Conditions: Use with caution in patients with liver or kidney problems; dosage adjustments may be necessary.
  • Heart Conditions: Caution is advised for individuals with heart rhythm disorders or heart problems, as this medicine may cause QT prolongation.
  • Alcohol: Avoid consuming alcohol during treatment as it may increase the risk of side effects, particularly liver complications.
  • Driving/Operating Machinery: May cause dizziness or seizures; avoid activities requiring mental focus if these side effects occur.
  • Drug Interactions: Inform your doctor about all other medications you are taking, as FLUTAS 400 MG Tablet can interact with drugs like oral hypoglycaemics, anticoagulants, anti-epileptic medicines, bronchodilators, and antiviral medications, potentially increasing their effects.
• Storage:
  • Store FLUTAS 400 MG Tablet in a cool and dry place.
  • Protect from light and moisture.
  • Keep out of reach of children.

What is FLUTAS 400 MG TABLET used for?

FLUTAS 400 MG TABLET, which contains fluconazole, is an antifungal medicine primarily used to treat a variety of fungal and yeast infections. These include infections of the mouth (oral thrush), throat (esophageal candidiasis), vagina (vaginal yeast infections), and other parts of the body like fingernails and toenails. It is also effective against systemic infections such as cryptococcal meningitis (a fungal infection in the brain) and other Candida infections affecting the bloodstream, urinary tract, lungs, and other organs. Additionally, it may be used to prevent fungal infections in individuals with weakened immune systems, such as patients undergoing bone marrow transplantation.

How does FLUTAS 400 MG TABLET work?

FLUTAS 400 MG TABLET works by inhibiting a fungal enzyme called 14-alpha demethylase, which is vital for the production of ergosterol. Ergosterol is a crucial component of the fungal cell membrane. By preventing ergosterol synthesis, fluconazole disrupts the integrity of the fungal cell membrane, leading to increased cellular permeability and ultimately stopping the growth and multiplication of the fungi, thereby treating the infection.

What is the usual dosage for FLUTAS 400 MG TABLET?

The dosage of FLUTAS 400 MG TABLET varies significantly depending on the type and severity of the fungal infection. For example, a single 150 mg dose might be prescribed for vaginal candidiasis. For more serious or systemic infections like cryptococcal meningitis, the typical adult dosage might be 400 mg on the first day, followed by 200 mg to 400 mg once daily for several weeks or even months. Pediatric dosages are calculated based on body weight and must be determined by a doctor. It is crucial to follow your doctor's instructions for the specific dosage and duration of treatment.

What are the possible side effects of FLUTAS 400 MG TABLET?

Common side effects of FLUTAS 400 MG TABLET can include headache, nausea, vomiting, diarrhea, stomach pain, changes in taste, and dizziness. More serious, though less common, side effects require immediate medical attention and may include severe skin rashes (potentially life-threatening), liver problems (indicated by yellowing of the skin or eyes, dark urine, pale stools, or persistent stomach pain), irregular heart rhythm (QT prolongation), and adrenal gland problems.

Is FLUTAS 400 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: High doses of fluconazole, especially when used long-term during the first trimester, have been linked to a rare pattern of birth defects. While a single low dose (e.g., 150 mg for vaginal candidiasis) is considered less risky, it is generally advised to avoid fluconazole during pregnancy unless other treatments are ineffective and the potential benefit outweighs the possible risks. If you are taking higher doses, effective birth control is recommended during treatment and for at least one week after the last dose.

Breastfeeding: Fluconazole passes into breast milk. While the amount infants receive through breast milk is usually less than therapeutic doses given directly to infants, it's still present. A single dose is unlikely to cause problems for the breastfed infant. For mothers on higher or prolonged doses, monitoring the infant for symptoms like stomach upset or diarrhea is recommended. Fluconazole is often considered compatible with breastfeeding, especially for shorter courses.

Can FLUTAS 400 MG TABLET be taken with other medications?

FLUTAS 400 MG TABLET can interact with numerous other medications, potentially altering their effects or increasing the risk of side effects. Important interactions can occur with:

• Blood thinners (e.g., warfarin): Increased risk of bleeding.
• Certain diabetes drugs (e.g., glyburide, glipizide): Increased risk of low blood sugar.
• Heart rhythm drugs (e.g., amiodarone, quinidine) and certain antidepressants (e.g., citalopram): Increased risk of irregular heart rhythms (QT prolongation).
• Anti-seizure medications (e.g., phenytoin, carbamazepine): Increased levels of these drugs, leading to potential toxicity.
• NSAIDs (e.g., ibuprofen, naproxen): Increased levels of NSAIDs.
• Rifampin: Can decrease the effectiveness of fluconazole.

Always inform your doctor and pharmacist about all prescription, over-the-counter medications, vitamins, and herbal supplements you are taking to prevent potential drug interactions.

What precautions should be taken while taking FLUTAS 400 MG TABLET?

Before taking FLUTAS 400 MG TABLET, inform your doctor if you have any pre-existing medical conditions, especially liver disease, kidney disease, heart problems (including irregular heartbeat or a history of QT prolongation), or electrolyte imbalances (such as low potassium levels). It is advisable to avoid alcohol consumption while on this medication, as it can increase the risk of liver damage. If you experience symptoms like dizziness, lightheadedness, fast heartbeat, or any signs of liver injury (yellowing skin/eyes, dark urine, pale stools, unusual fatigue, stomach pain), seek medical attention immediately.

What happens if a dose of FLUTAS 400 MG TABLET is missed?

If you miss a dose of FLUTAS 400 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this could increase the risk of side effects.

How should FLUTAS 400 MG TABLET be stored?

FLUTAS 400 MG TABLET should be stored at room temperature, generally below 30°C (86°F). Keep the tablets in their original, tightly closed container in a cool, dry place, protected from direct light, heat, and moisture. It is important to store all medications out of the reach of children. Avoid storing it in the bathroom or kitchen, as these areas often have fluctuating temperatures and humidity, which can affect the medicine's potency.