Subitral Ds 100 Mg

SUBITRAL DS 100 MG Capsule

SUBITRAL DS 100 MG Capsule is an antifungal medication primarily used to treat a wide range of fungal infections in various parts of the body. Manufactured by AKUMS DRUGS & PHARMACEUTICALS LTD (though some sources also list Indoco Remedies Ltd.), this medicine is available in capsule form.

Composition Each capsule of SUBITRAL DS 100 MG contains 100 mg of Itraconazole. Itraconazole is an azole antifungal that works by inhibiting the growth of fungi by preventing the formation of ergosterol, a crucial component of fungal cell membranes. This action disrupts the fungal cell structure, leading to the leakage of cellular contents and ultimately killing the fungi.

Uses SUBITRAL DS 100 MG is prescribed for various fungal infections, including:

• Fungal infections of the skin, hair, and nails (such as ringworm, athlete's foot, jock itch, and onychomycosis).
• Fungal infections of the mouth and throat (oral thrush).
• Vaginal yeast infections (candidiasis).
• Systemic fungal infections affecting internal organs like the lungs, including conditions such as aspergillosis, histoplasmosis, blastomycosis, and cryptococcal infection.
• It may also be used to prevent fungal infections in immunocompromised patients.

Dosage and Administration SUBITRAL DS 100 MG Capsules should be taken orally with food, typically once or twice daily, or as prescribed by your doctor. The capsules should be swallowed whole and not crushed, chewed, or broken. It is crucial to complete the full course of treatment as prescribed, even if symptoms improve, to prevent the infection from returning or developing resistance. Avoid taking antacids within 2 hours of this medicine; if taking stomach acid-reducing medications, it may be advised to take Subitral DS with a cola drink to aid absorption.

Side Effects Commonly reported side effects include:

• Nausea, vomiting, diarrhea, abdominal pain, constipation, dyspepsia.
• Headache, dizziness, fatigue, tiredness.
• Skin rash, itching, sensitivity to light.
• Irregular menstrual cycle, sinusitis, runny nose, cough, sneezing, throat pain, back pain.
• Blurred or double vision, taste changes, ringing in ears.

Serious side effects, though rare, warrant immediate medical attention:

• Signs of allergic reaction such as severe skin rash, difficulty breathing, or swelling of the face, lips, tongue, or throat.
• Liver problems, indicated by symptoms like yellowing of the eyes or skin (jaundice), dark urine, pale stools, severe lack of appetite, nausea, vomiting, tiredness, stomach pain, muscle weakness, or hair loss.
• Heart failure symptoms, including chest pain or difficulty breathing.
• Tingling, numbness, or weakness in the limbs.
• Severe skin disorders with peeling or rashes with fever.

Precautions

• Inform your doctor if you are pregnant, breastfeeding, or planning pregnancy, as it is generally not recommended during these periods.
• Exercise caution and inform your doctor if you have a history of liver disease, kidney disease, heart failure or other cardiac conditions, weakened immunity, AIDS, or a known allergy to Itraconazole or other azole antifungals.
• Avoid alcohol consumption during treatment as it may increase the risk of liver damage.
• Regular monitoring of liver function may be necessary during treatment.
• This medicine may cause dizziness, blurred, or double vision; therefore, caution is advised when driving or operating machinery.
• Not generally recommended for children under 12 years of age or elderly patients without specific doctor's advice and potential dose adjustments.
• Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, as Subitral DS 100 MG can interact with various medicines (e.g., antiarrhythmics, antihistamines like astemizole, benzodiazepines, cholesterol-lowering medicines, and certain medications for blood pressure, migraine, gout, and digestive issues).
• Avoid consuming grapefruit or grapefruit juice while on this medication, as it may increase the level of Itraconazole in the body.
• Patients with hereditary galactose intolerance should use this medicine with caution.

Storage Store SUBITRAL DS 100 MG Capsules at room temperature, ideally between 15°C and 30°C (or below 30°C). Keep the capsules in their original packaging, away from direct sunlight and moisture. Always keep this medicine out of the sight and reach of children. Check the expiry date before use and discard if the medicine has expired.

What is SUBITRAL DS 100 MG used for?

SUBITRAL DS 100 MG is an antifungal medication primarily used to treat a wide range of fungal infections. These include infections of the skin, nails (onychomycosis), mouth (oral thrush), throat, and vagina (yeast infections). It is also effective against more serious systemic fungal infections such as aspergillosis, histoplasmosis, and blastomycosis, as well as dermatophyte infections like athlete's foot and ringworm.

How does SUBITRAL DS 100 MG work?

SUBITRAL DS 100 MG contains Itraconazole as its active ingredient. It works by inhibiting the growth of fungi by disrupting or destroying their cell membranes. This action specifically targets the production of ergosterol, a vital component of the fungal cell membrane, which leads to the leakage of essential cell contents and ultimately the death of the fungal cells, clearing the infection.

What is the usual dosage for SUBITRAL DS 100 MG?

The typical dosage for SUBITRAL DS 100 MG is one capsule once or twice daily, as prescribed by your doctor. It is crucial to swallow the capsule whole, and it should generally be taken with food to enhance absorption. The exact dose and duration of treatment will depend on the specific type and severity of the fungal infection.

What are the possible side effects of SUBITRAL DS 100 MG?

Common side effects may include nausea, headache, abdominal pain, diarrhea, rash, dizziness, vomiting, constipation, and indigestion. More serious, though rare, side effects can occur, such as liver toxicity (indicated by symptoms like yellowing of the skin or eyes, dark urine, pale stools, severe loss of appetite, extreme fatigue, or stomach pain), heart failure, severe allergic reactions (e.g., severe skin rash, difficulty breathing, swelling of the face, lips, tongue, or throat), tingling, numbness, weakness in the limbs, or irregular heartbeat. If you experience any severe side effects, seek immediate medical attention.

Is SUBITRAL DS 100 MG safe during pregnancy or breastfeeding?

SUBITRAL DS 100 MG is generally not recommended for use during pregnancy or for individuals who might become pregnant, as it carries an increased risk of fetal harm, including severe birth defects. It is advised to use a reliable method of contraception to prevent pregnancy while taking this medicine. During breastfeeding, SUBITRAL DS 100 MG should be avoided as its active ingredient is known to pass into breast milk and may affect the baby.

Can SUBITRAL DS 100 MG be taken with other medications?

SUBITRAL DS 100 MG can interact with several other medications, so it is important to inform your doctor about all medicines you are currently taking, including over-the-counter drugs and herbal supplements. For example, it is advised to avoid taking antacids or other indigestion remedies within 1-2 hours of taking SUBITRAL DS 100 MG, as they can reduce its absorption. If antacids are necessary, taking SUBITRAL DS 100 MG with a cola drink may help. Significant interactions can occur with certain medications used for allergies, cholesterol-lowering drugs, medicines for irregular heartbeats, HIV infection, bacterial infections, tuberculosis, epilepsy, and St. John's Wort. Additionally, fentanyl should not be taken with SUBITRAL DS 100 MG due to potential severe breathing complications.

What precautions should be taken while using SUBITRAL DS 100 MG?

Before starting SUBITRAL DS 100 MG, inform your doctor if you have a history of hypersensitivity to Itraconazole or other azole antifungals, or if you have any pre-existing medical conditions such as active liver disease, heart failure, severe cardiac conditions, or kidney disease. Your doctor may recommend regular monitoring of your liver function, especially during prolonged treatment. It is advisable to avoid alcohol consumption and grapefruit or grapefruit juice while on this medication, as they may increase the risk of side effects or alter drug levels. Do not stop the medication prematurely, even if symptoms improve, to prevent the infection from returning or developing resistance. Since dizziness can be a side effect, exercise caution when driving or operating machinery.

What happens if a dose of SUBITRAL DS 100 MG is missed?

If you miss a dose of SUBITRAL DS 100 MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should SUBITRAL DS 100 MG be stored?

SUBITRAL DS 100 MG capsules should be stored in a cool and dry place, ideally between 15°C and 30°C. Keep them in their original packaging, away from direct sunlight and moisture. Always ensure the medicine is kept out of reach of children. It is also important to check the expiry date before use and discard any expired medication.