Ceftum 500mg 10tab

CEFTUM 500MG 10TAB by GSK LTD

Name

Common Name: Ceftum 500mg Tablet Brand Name: Ceftum (manufactured by GSK Ltd.)

Composition

Each film-coated tablet contains Cefuroxime Axetil IP equivalent to Cefuroxime 500 mg.

Uses

Ceftum 500mg Tablet is an antibiotic from the cephalosporin class, used to treat a wide range of bacterial infections. It is effective against various infections, including:

• Respiratory tract infections: Bronchitis, pneumonia, laryngitis, sinusitis, tonsillitis, pharyngitis.
• Ear infections: Otitis media.
• Urinary tract infections (UTIs): Including pyelonephritis, cystitis, and urethritis.
• Skin and soft tissue infections: Such as cellulitis and impetigo.
• Sexually transmitted infections: Gonorrhoea and early-stage Lyme disease.
• It can also be used to prevent infections during surgery.

Dosage and Administration

Adults typically take Ceftum 500 mg orally twice a day. It should be taken with food to enhance absorption and minimize stomach upset. The tablets should be swallowed whole and not crushed or split. The usual course of therapy ranges from 5 to 10 days, depending on the type and severity of the infection, and the full course should be completed as prescribed, even if symptoms improve.

Side Effects

Common side effects may include:

• Rash
• Vomiting
• Allergic reactions
• Increased liver enzymes
• Nausea
• Diarrhea
• Headache
• Dizziness
• Stomach pain
• Weakness

Serious side effects are less common but can include severe, persistent diarrhea (potentially Clostridioides difficile-associated diarrhea) or severe allergic reactions.

Precautions

• Allergies: Do not take if allergic to cefuroxime, any other cephalosporin antibiotics, or other beta-lactam antibiotics like penicillin.
• Kidney/Liver Issues: Use with caution in patients with kidney problems, as dosage adjustments may be necessary. Limited information is available for liver disease, so consult a doctor.
• Pregnancy and Breastfeeding: Generally considered safe during pregnancy if prescribed by a doctor. It enters breast milk in low amounts during breastfeeding; however, infants should be monitored for adverse effects like diarrhea or yeast infections.
• Drug Interactions:
  • Antacids and medications that reduce stomach acidity may lower Ceftum's absorption.
  • Probenecid can increase cefuroxime levels in the blood.
  • Cefuroxime may increase the effects of blood thinners like warfarin.
  • It may reduce the effectiveness of live bacterial vaccines (e.g., Typhoid) and combined oral contraceptives.
• Other Conditions: Caution is advised in patients with a history of seizure disorders, colitis, or phenylketonuria.

Storage

Store Ceftum tablets at room temperature, between 15°C and 30°C (59°F and 86°F), away from excessive heat, moisture, and direct sunlight. Keep the container tightly closed and out of the reach of children and pets. Discard any unused or expired medication properly.

Here are frequently asked questions about CEFTUM 500MG, an antibiotic manufactured by GSK LTD.

What is CEFTUM 500MG used for?

CEFTUM 500MG is an antibiotic containing cefuroxime, a second-generation cephalosporin, used to treat various bacterial infections. It is effective against infections of the respiratory tract (such as bronchitis and pneumonia), ears, throat (tonsillitis, pharyngitis), sinuses, urinary tract, skin, soft tissues, bones, and joints. It can also be prescribed for conditions like gonorrhea and Lyme disease, and sometimes used to prevent infections during surgery.

How does CEFTUM 500MG work?

CEFTUM 500MG works by killing bacteria. Its active ingredient, cefuroxime, interferes with the bacteria's ability to build and maintain their cell walls. By binding to specific proteins (penicillin-binding proteins) in the bacterial cell wall, it prevents the final steps of cell wall synthesis, causing the bacterial cell to weaken, break apart, and die.

What is the usual dosage for CEFTUM 500MG?

For adults, the typical dosage is 500 mg taken orally twice a day. The duration of treatment usually ranges from 5 to 10 days, depending on the type and severity of the infection, as determined by your doctor. It is crucial to complete the full course of medication, even if you start feeling better, to ensure the infection is fully treated and to prevent antibiotic resistance.

Should CEFTUM 500MG be taken with food?

Yes, CEFTUM 500MG tablets should generally be taken after food to improve absorption and minimize the risk of stomach irritation or upset.

What are the possible side effects of CEFTUM 500MG?

Common side effects may include rash, vomiting, nausea, diarrhea, headache, dizziness, stomach pain, and increased liver enzymes. Diarrhea is a frequent side effect; if it becomes severe, persistent, or contains blood or mucus, you should consult your doctor immediately. Other possible, less common side effects include muscle pain, weakness, redness of skin, fever, or an unpleasant taste in the mouth.

Is CEFTUM 500MG safe during pregnancy or breastfeeding?

Pregnancy: CEFTUM 500MG is generally considered safe for use during pregnancy, and animal studies have shown little to no adverse effects on the developing baby. However, it should only be used if prescribed by your doctor.

Breastfeeding: CEFTUM 500MG is typically safe during breastfeeding as only low amounts are excreted in breast milk. Nevertheless, it should be used cautiously, and the infant should be monitored for potential adverse effects such as diarrhea or yeast infection. Always consult your doctor before taking this medication while breastfeeding.

Can CEFTUM 500MG be taken with other medications?

CEFTUM 500MG can interact with certain medications. Antacids and drugs that reduce stomach acid (e.g., proton pump inhibitors) may decrease its absorption, so it's advised to take CEFTUM at least 1 hour before or 2 hours after these medications. Probenecid can increase the levels of cefuroxime in the blood. CEFTUM may also reduce the effectiveness of oral contraceptives and could potentially increase the effects of blood thinners like warfarin. It can also interfere with the efficacy of live bacterial vaccines (e.g., Typhoid, BCG). Always inform your doctor about all medications, supplements, and herbal products you are currently taking.

What precautions should be taken while taking CEFTUM 500MG?

Inform your doctor about any history of allergies, especially to cephalosporin or penicillin antibiotics, as well as kidney or liver problems, stomach ulcers, abdominal pain, or seizure disorders. Since CEFTUM 500MG can cause dizziness, exercise caution when driving or operating machinery. It is an antibiotic and is not effective against viral infections like the common cold or flu.

What should I do if I miss a dose of CEFTUM 500MG?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should CEFTUM 500MG be stored?

Store CEFTUM 500MG tablets at room temperature, typically between 15°C and 30°C (59°F and 86°F), away from excessive heat, moisture, and direct sunlight. Keep the container tightly closed and out of the reach of children and pets. Properly discard any unused or expired medication.