Empahope M 1000mg Tab

EMPAHOPE M 1000MG Tablet

EMPAHOPE M 1000MG Tablet is a combination medication manufactured by Macleods Pharmaceuticals Ltd., primarily used in the management of Type 2 Diabetes Mellitus.

Composition

EMPAHOPE M 1000MG Tablet contains two active ingredients:

• Empagliflozin: 12.5 mg
• Metformin: 1000 mg

Empagliflozin is a sodium-glucose co-transporter-2 (SGLT2) inhibitor, which helps remove excess sugar from the body through urine. Metformin is a biguanide that lowers blood sugar by reducing glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

Uses

EMPAHOPE M 1000MG Tablet is prescribed for the treatment of Type 2 Diabetes Mellitus to improve blood sugar control in adults, often in conjunction with diet and exercise. Beyond glycemic control, it offers additional benefits:

• Cardiovascular benefits: Reduces the risk of heart attacks, strokes, and other cardiovascular events in patients with Type 2 diabetes and heart disease.
• Renal protection: May help protect kidney function and slow the progression of diabetic kidney disease.
• Blood pressure reduction: Can contribute to lowering blood pressure levels.
• Prevention of complications: Helps prevent serious diabetes complications such as kidney damage, blindness, and nerve damage.

Dosage and Administration

Take EMPAHOPE M 1000MG Tablet orally as advised by your doctor. It can be taken with or without food, but taking it with meals may help reduce stomach upset. It is generally recommended to take it at the same time each day. Swallow the tablet whole; do not chew, crush, or break it. Do not stop taking this medicine without consulting your doctor, as abrupt discontinuation can lead to increased blood sugar levels and a higher risk of complications.

Side Effects

Common Side Effects:

• Frequent urination
• Mild skin rash or itchy skin
• Nausea, vomiting, diarrhea, stomach ache, loss of appetite
• Taste changes
• Urinary tract infection
• Genital fungal infection
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Hypoglycemia (low blood glucose level) when used with other antidiabetic medicines, alcohol, or if meals are delayed or missed.
• Joint pain

Serious Side Effects:

• Lactic Acidosis: Symptoms may include trouble breathing, unusual muscle pain, weakness, irregular heartbeats, rapid weight loss, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to your breath, a sweet or metallic taste in your mouth, or a different odor to your urine or sweat. Seek immediate medical attention if these occur.
• Dehydration: May occur due to increased urination.

Precautions

• Allergies: Do not use if you are allergic to empagliflozin, metformin, or any other components of the tablet.
• Pregnancy and Breastfeeding: Generally considered unsafe during pregnancy and breastfeeding; consult your doctor.
• Alcohol: Avoid excessive alcohol intake as it may worsen side effects like lactic acidosis and increase the risk of low blood sugar levels.
• Kidney and Liver Conditions: Unsafe for patients with severe kidney disease and should be avoided; use with caution in patients with liver disease. Inform your doctor about any kidney or liver problems.
• Driving: May decrease alertness, affect vision, or cause sleepiness and dizziness. Avoid driving if you experience these symptoms.
• Other Medical Conditions: Inform your doctor if you have Type 1 diabetes, metabolic acidosis, diabetic pre-coma, severe infection, dehydration, or any condition affecting kidneys.
• Hydration: Drink plenty of fluids to help prevent dehydration.
• Hygiene: Maintain good genital hygiene to help prevent fungal and urinary tract infections.
• Interactions: Inform your doctor about all current medications, supplements, or herbal products, especially diuretics, as they can increase the risk of dehydration.

Storage

Store EMPAHOPE M 1000MG Tablet in a cool and dry place, away from direct sunlight and moisture, at temperatures below 25°C or 30°C. Keep out of reach of children and pets.

EMPAHOPE M 1000MG TABLET is a combination medication containing Empagliflozin (12.5mg) and Metformin (1000mg), manufactured by Macleods Pharmaceuticals Ltd.. It is prescribed for the management of Type 2 Diabetes Mellitus.

Here are some frequently asked questions about EMPAHOPE M 1000MG TABLET:

What is EMPAHOPE M 1000MG Tablet used for?

EMPAHOPE M 1000MG Tablet is used to treat Type 2 Diabetes Mellitus in adults, alongside diet and exercise, to improve blood sugar control. It also helps in preventing serious complications of diabetes such as kidney damage, blindness, nerve damage, and can reduce the risk of cardiovascular death and hospitalization for heart failure in patients with Type 2 diabetes and established cardiovascular disease.

How does EMPAHOPE M 1000MG Tablet work?

This medicine combines two anti-diabetic medications: Empagliflozin and Metformin. Empagliflozin works by blocking the sodium-glucose co-transporter-2 (SGLT-2) in the kidneys, which reduces the reabsorption of glucose and increases its excretion in the urine. Metformin, belonging to the biguanide class, decreases glucose production in the liver, delays glucose absorption from the intestines, and improves the body's sensitivity to insulin. Together, they more effectively lower blood glucose levels.

What is the usual dosage for EMPAHOPE M 1000MG Tablet?

The dosage of EMPAHOPE M 1000MG Tablet is determined by your doctor. It should be taken with food at the same time every day. Do not cut, break, or chew the tablet. Do not exceed the recommended dose. For similar empagliflozin and metformin combinations, the dose is usually not more than 25 mg of empagliflozin and 2000 mg of metformin per day.

What are the possible side effects of EMPAHOPE M 1000MG Tablet?

Common side effects may include frequent urination, urinary tract infections (UTIs), genital fungal infections, nausea, vomiting, diarrhea, abdominal pain, loss of appetite, taste changes, and joint pain. Drinking plenty of fluids can help prevent dehydration. A serious, though rare, side effect of metformin is lactic acidosis, which can cause symptoms like trouble breathing, unusual muscle pain, weakness, and irregular heartbeats.

Is EMPAHOPE M 1000MG Tablet safe during pregnancy or breastfeeding?

EMPAHOPE M 1000MG Tablet is generally not recommended during pregnancy, especially during the second and third trimesters, due to potential risks to the unborn baby's kidney development. Similarly, it is usually not recommended during breastfeeding because it is not known how much passes into breast milk and there's a theoretical risk to the infant's developing kidneys. Always consult your doctor to discuss the risks and benefits.

Can EMPAHOPE M 1000MG Tablet be taken with other medications?

It is crucial to inform your doctor about all medications, supplements, and herbal products you are currently taking or plan to take, to avoid undesirable side effects or interactions. For instance, EMPAHOPE M Tablet may lower the levels of lithium in the blood. It can be used in combination with insulin under the supervision of a doctor.

What precautions should be taken while taking EMPAHOPE M 1000MG Tablet?

This medicine is not suitable for individuals with Type 1 Diabetes Mellitus, severe kidney or liver disease. Avoid consuming alcohol while taking this medication, as it can increase the risk of lactic acidosis and low blood sugar levels. Stay well-hydrated, especially during hot weather or physical activity, and maintain good hygiene to prevent fungal infections. Regular monitoring of blood sugar levels is important. It is not recommended for anyone aged 85 years or older.

What happens if a dose of EMPAHOPE M 1000MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.

How should EMPAHOPE M 1000MG Tablet be stored?

Store EMPAHOPE M 1000MG Tablet in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. The typical storage temperature is between 10ºC to 25ºC or below 30ºC.