Abvida M 50/500 Tablet

ABVIDA M 50/500 TABLET

Name:

• Brand Name: ABVIDA M 50/500 TABLET, ABVIDA M 50/500mg Eazy Glide Tablet SR
• Common Name: Metformin and Vildagliptin (combination)

Composition: ABVIDA M 50/500 TABLET contains two active ingredients:

• Vildagliptin: 50 mg
• Metformin: 500 mg

Uses: This medicine is primarily used to manage Type 2 Diabetes Mellitus in adults. It is prescribed when diet and exercise alone, or other single antidiabetic agents, are insufficient to control blood sugar levels. ABVIDA M works by increasing insulin secretion, decreasing glucagon production, reducing glucose production in the liver, and improving the body's sensitivity to insulin. This helps in controlling both fasting and post-meal blood sugar levels and can help prevent serious diabetes complications like kidney damage, eye damage, nerve problems, and cardiovascular issues.

Dosage and Administration: ABVIDA M 50/500 TABLET is typically taken once or twice daily, as prescribed by a physician, often with or after meals to minimize gastrointestinal upset. The tablet should be swallowed whole with water and not crushed, chewed, or broken. Dosage and duration depend on individual factors and medical conditions, and it's crucial not to alter the dose or stop the medication without consulting a doctor.

Side Effects: Common side effects include diarrhea, stomach pain, nausea, vomiting, loss of appetite, metallic taste, headache, dizziness, tremor, joint pain, tiredness, constipation, and low blood glucose (hypoglycemia). Serious but rare side effects include lactic acidosis (symptoms like severe vomiting, stomach pain, difficulty breathing), pancreatitis (severe abdominal pain), and serious skin reactions.

Precautions:

• Pregnancy and Breastfeeding: Not recommended during pregnancy and contraindicated for breastfeeding women unless advised by a doctor.
• Alcohol: Avoid alcohol consumption as it increases the risk of lactic acidosis.
• Organ Impairment: Contraindicated or requires caution in patients with severe kidney or liver disease, heart conditions, or a history of pancreatitis.
• Other: Inform your doctor about all other medications being taken due to potential drug interactions. Monitor blood sugar levels regularly. Not suitable for children under 18 years.

Storage: Store at room temperature, ideally between 15-30°C, in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

ABVIDA M 50/500 TABLET is a combination medication used to manage Type 2 diabetes mellitus in adults. It combines two active ingredients, Vildagliptin and Metformin, to help control blood sugar levels when diet and exercise alone are insufficient.

What is ABVIDA M 50/500 TABLET used for?

ABVIDA M 50/500 TABLET is primarily used to manage Type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone, or treatment with either Vildagliptin or Metformin by themselves, do not provide adequate blood sugar control.

How does ABVIDA M 50/500 TABLET work?

This medication works through the combined action of its two components:

• Vildagliptin (50 mg): This is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It increases the levels of incretin hormones, which stimulate the pancreas to release more insulin when blood glucose levels are high and decrease the production of glucagon, a hormone that raises blood sugar.
• Metformin (500 mg): This is a biguanide that lowers blood sugar by reducing the amount of glucose produced by the liver, decreasing the absorption of glucose from the intestines, and improving the body's sensitivity to insulin, allowing cells to utilize glucose more effectively. Together, these actions help to control both fasting and post-meal blood sugar levels.

What is the usual dosage for ABVIDA M 50/500 TABLET?

ABVIDA M 50/500 TABLET is typically taken once or twice daily, as prescribed by your doctor. It should be taken with or after meals to help reduce gastrointestinal side effects. The exact dosage will depend on your medical condition and response to treatment.

What are the possible side effects of ABVIDA M 50/500 TABLET?

Common side effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, stomach pain, and loss of appetite. Other common side effects can be headache, dizziness, and low blood sugar (hypoglycemia), especially when used with other antidiabetic medicines. A rare but serious side effect is lactic acidosis, which requires immediate medical attention if symptoms like persistent nausea, vomiting, stomach pain, deep/rapid breathing, or general weakness occur.

Is ABVIDA M 50/500 TABLET safe during pregnancy or breastfeeding?

ABVIDA M 50/500 TABLET is generally not recommended during pregnancy or breastfeeding. Limited studies suggest potential harmful effects on a developing baby during pregnancy, and its components are known to pass into breast milk. Always consult your doctor to discuss the potential risks and benefits if you are pregnant, planning to conceive, or breastfeeding.

Can ABVIDA M 50/500 TABLET be taken with other medications?

ABVIDA M 50/500 TABLET can interact with several other medications. These include cationic medicines (e.g., amiloride, digoxin, morphine), other antidiabetic agents (which may increase the risk of hypoglycemia), glucocorticoids, beta-2 agonists, diuretics, NSAIDs, ACE inhibitors, angiotensin II receptor antagonists, and thyroid hormones. It is crucial to inform your doctor about all medications, supplements, and herbal products you are taking to avoid potential interactions.

What precautions should be taken while using ABVIDA M 50/500 TABLET?

This medication is not suitable for individuals with Type 1 diabetes, severe kidney disease, severe liver disease, or diabetic ketoacidosis. Alcohol consumption should be avoided as it can increase the risk of lactic acidosis. Caution is advised for patients with a history of pancreatitis, heart problems, or low vitamin B12 levels. Regular monitoring of kidney function and blood sugar levels is essential during treatment.

What happens if a dose of ABVIDA M 50/500 TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one, as this may increase the risk of side effects.

How should ABVIDA M 50/500 TABLET be stored?

Store ABVIDA M 50/500 TABLET at room temperature, ideally between 15-30°C (or below 30°C). Keep the medicine in a dry place, away from direct sunlight, moisture, and heat. Ensure it is stored out of reach of children and pets. Always check the expiry date and discard any expired medication properly.