New Triclazone 80

NEW TRICLAZONE 80 by SUN PHARMA LABORATORIES LTD.

Name:

• Common Name: NEW TRICLAZONE 80 Tablet
• Brand Name: NEW TRICLAZONE 80

Composition:

• NEW TRICLAZONE 80 is a combination of three antidiabetic medicines: Gliclazide (80 mg), Metformin (500 mg), and Pioglitazone (15 mg).

Uses: NEW TRICLAZONE 80 Tablet is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is typically used when diet, exercise, weight loss, or single/dual antidiabetic therapies are not sufficient to achieve adequate blood sugar control. This medicine works by increasing insulin release from the pancreas, enhancing the body's sensitivity to insulin, reducing glucose production in the liver, and delaying glucose absorption from the intestines.

Dosage and Administration:

• Take NEW TRICLAZONE 80 Tablet with food, ideally at the same time each day.
• Swallow the tablet whole with a glass of water; do not crush or chew it.
• Your doctor will determine the appropriate dose, which may be adjusted based on your blood sugar levels.
• Do not discontinue this medicine without consulting your doctor.

Side Effects:

• Common Side Effects: Low blood glucose levels (hypoglycemia, indicated by sweating, dizziness, headache), nausea, changes in taste, diarrhea, stomach pain, headache, dizziness, edema (swelling), blurred vision, bone fracture, upper respiratory tract infections, and weight gain.
• Serious Side Effects: These can include severe allergic reactions (rash, swelling, difficulty breathing), very low blood sugar, signs of lactic acidosis (cold hands/feet, unusual muscle pain, trouble breathing), and symptoms of heart failure (unusual shortness of breath, rapid weight increase, localized swelling). Seek immediate medical attention if you experience serious side effects.

Precautions:

• Important Warning: The combination of active ingredients in NEW TRICLAZONE 80 is banned in India due to serious side effects.
• This medicine is not recommended for individuals with Type 1 diabetes mellitus, diabetic ketoacidosis, severe kidney or liver disease, bladder cancer, severe heart failure, or metabolic acidosis.
• Avoid alcohol consumption while taking this medication as it can increase the risk of low blood sugar.
• Consult your doctor if you are pregnant or breastfeeding, as this medicine is generally not recommended during these periods.
• Caution is advised in patients with pre-existing heart problems.
• Regular monitoring of blood sugar levels, blood cell counts, and liver function is necessary.
• Inform your doctor about all other medications you are taking to avoid potential drug interactions.

Storage:

• Store NEW TRICLAZONE 80 Tablet at room temperature, ideally below 30°C.
• Keep out of reach of children.

NEW TRICLAZONE 80 by SUN PHARMA LABORATORIES LTD. is a combination medication used to manage Type 2 Diabetes Mellitus. It contains Gliclazide, Metformin, and Pioglitazone, working together to help control blood sugar levels in adults.

What is NEW TRICLAZONE 80 used for?

NEW TRICLAZONE 80 is prescribed for adults with Type 2 Diabetes Mellitus when diet, exercise, and treatment with single or dual antidiabetic agents have not adequately controlled blood sugar levels. It helps to lower blood glucose and can aid in preventing long-term complications of diabetes such as kidney damage, eye damage, nerve problems, and limb loss.

How does NEW TRICLAZONE 80 work?

This medication combines three active ingredients:

• Gliclazide: Works by stimulating the pancreas to release more insulin.
• Metformin: Reduces glucose production by the liver, increases the body's sensitivity to insulin, improves glucose uptake and utilization by cells, and delays glucose absorption from the intestines.
• Pioglitazone: Improves insulin sensitivity in muscle and fat tissues, making it easier for the body to use available insulin, and also decreases the amount of glucose released by the liver. Together, these actions help to effectively lower elevated blood sugar levels.

What is the usual dosage for NEW TRICLAZONE 80?

The dosage of NEW TRICLAZONE 80 is determined by your doctor based on your individual condition and how well your blood sugar levels are controlled. It should be taken with food, preferably at the same time each day. It is important to follow your doctor's instructions precisely and not to crush, break, or chew the tablet.

What are the possible side effects of NEW TRICLAZONE 80?

Common side effects may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, sore throat, common cold, decreased blood sugar levels (hypoglycemia), altered sense of taste, joint pain, fracture, and weight gain.

More serious side effects, though less common, can include signs of lactic acidosis (e.g., cold hands or feet, unusual muscle pain, trouble breathing, severe tiredness, stomach pains), symptoms of heart failure (e.g., unusual shortness of breath, rapid weight gain, swelling), or severe allergic reactions. If you experience any severe or persistent side effects, contact your doctor immediately.

Is NEW TRICLAZONE 80 safe during pregnancy or breastfeeding?

Pregnancy: There is limited information on the effects of NEW TRICLAZONE 80 during human pregnancy. Animal studies have shown harmful effects on the developing baby, and it is generally considered probably unsafe. Your doctor will weigh the potential benefits against the risks if prescribing this medicine during pregnancy.

Breastfeeding: NEW TRICLAZONE 80 is considered probably unsafe during breastfeeding, as the drug may pass into breast milk and potentially harm the infant. It is generally not recommended while breastfeeding.

Can NEW TRICLAZONE 80 be taken with other medications?

NEW TRICLAZONE 80 can interact with various medications. For example, certain pain killers (like phenylbutazone, gemfibrozil), warfarin, and some antibiotics (like miconazole and fluoroquinolones) can alter its effects or lead to imbalances in blood sugar. Other medications such as danazol, chlorpromazine, glucocorticoids, and verapamil may also interact with NEW TRICLAZONE 80. It is crucial to inform your doctor about all other medicines, herbal preparations, and supplements you are currently taking to avoid potential drug interactions.

What precautions should be taken while taking NEW TRICLAZONE 80?

Do not take NEW TRICLAZONE 80 if you have Type 1 diabetes, severe kidney or liver disease, heart failure, diabetic ketoacidosis, or a history of bladder cancer.

Caution is advised if you have pre-existing heart problems, kidney or liver issues, certain eye conditions (macular oedema), or a history of reduced blood count or weaker bone strength. Alcohol consumption should be avoided as it can increase the risk of lactic acidosis and low blood sugar. Prolonged fasting should also be avoided due to the risk of hypoglycemia. If you experience dizziness or visual disturbances, avoid driving or operating heavy machinery. Always inform your doctor about all your medical conditions and before any planned surgery.

What happens if a dose of NEW TRICLAZONE 80 is missed?

If you miss a dose of NEW TRICLAZONE 80, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should NEW TRICLAZONE 80 be stored?

NEW TRICLAZONE 80 should be stored below 25°C (or 30°C) in a cool and dry place. Protect it from light and moisture. Always keep the medication out of the reach and sight of children and pets.