Clavilip 10 Mg Capsule (15 Cap)

CLAVILIP 10 MG CAPSULE

CLAVILIP 10 MG CAPSULE is a medicine manufactured by INTAS PHARMACEUTICALS LTD.

• Composition: Each capsule contains Atorvastatin (10 mg) and Clopidogrel (75 mg).

• Uses: CLAVILIP 10 MG CAPSULE is primarily used to manage high blood cholesterol and triglyceride levels, especially when diet and lifestyle changes alone have been insufficient. It is also prescribed to reduce the risk of cardiovascular events such as heart attacks, strokes, angina (chest pain), and to prevent complications after angioplasty or stenting procedures in individuals at high risk. Atorvastatin works by lowering "bad" cholesterol (LDL) and triglycerides, while increasing "good" cholesterol (HDL). Clopidogrel acts as an antiplatelet agent, preventing blood clots from forming.

• Dosage and Administration: This medicine should be taken orally with or without food, as prescribed by your doctor. It is important to take it regularly at the same time each day for optimal effectiveness. Do not crush, chew, or open the capsule. The exact dose and duration of treatment will depend on the patient's condition and should be determined by a healthcare professional.

• Side Effects:

  • Common: Headache, dizziness, nausea, indigestion, stomach pain, diarrhoea, constipation, muscle pain, joint pain, back pain, rash, nosebleeds, drowsiness, and sleeplessness.
  • Serious (seek immediate medical attention): Unexpected or unusual bleeding or bruising, signs of liver problems (e.g., yellowing of skin/eyes), or signs of infection/extreme tiredness due to a decrease in certain blood cells.

• Precautions:

  • Contraindications: Do not use if allergic to Atorvastatin, Clopidogrel, or any other ingredients. It is contraindicated in patients with active liver disease, active bleeding issues (such as peptic ulcer or brain hemorrhage), and is not recommended for pregnant or breastfeeding women.
  • Warnings: Inform your doctor if you have liver or kidney disease, muscle pain or weakness, diabetes, lung disease, a recent history of stroke, or any scheduled surgery. CLAVILIP 10 MG CAPSULE may increase the risk of bleeding, so caution is advised during activities that may cause injury. It may need to be stopped before surgery or dental procedures to avoid excessive bleeding. Avoid alcohol consumption as it can increase the risk of stomach bleeding and liver problems. Grapefruit and grapefruit juice should be avoided as they can increase atorvastatin levels.
  • Drug Interactions: Inform your doctor about all other medicines, herbal preparations, and supplements you are taking, especially blood thinners (like warfarin), HIV protease inhibitors (like ritonavir), antifungals (like itraconazole), and immunosuppressants (like cyclosporine), as these can interact with CLAVILIP 10 MG CAPSULE. Paracetamol is generally safe for pain relief, but other painkillers should be avoided due to an increased risk of bleeding.

• Storage: Store the medicine below 25°C or 30°C in a clean and dry place, protected from moisture, sunlight, and heat. Keep it out of reach of children and pets. Do not use after the expiry date.

Here are some frequently asked questions about CLAVILIP 10 MG CAPSULE:

What is CLAVILIP 10 MG CAPSULE used for?

CLAVILIP 10 MG CAPSULE is primarily used for the prevention of heart attacks, strokes, and other cardiovascular events in individuals at high risk. It also helps in managing high cholesterol and triglyceride levels in the blood.

How does CLAVILIP 10 MG CAPSULE work?

This medicine is a combination of two active ingredients: Atorvastatin and Clopidogrel. Atorvastatin works by lowering "bad" cholesterol (LDL) and triglycerides, while slightly increasing "good" cholesterol (HDL), thereby reducing the risk of heart diseases. Clopidogrel is an antiplatelet agent that prevents platelets from sticking together and inhibiting blood clot formation, helping to keep blood flowing smoothly in your body.

What is the usual dosage for CLAVILIP 10 MG CAPSULE?

The dosage of CLAVILIP 10 MG CAPSULE should be taken exactly as prescribed by your doctor. It is typically taken once daily, with or without food, at the same time each day to help with adherence. Do not exceed the recommended daily dose.

What are the possible side effects of CLAVILIP 10 MG CAPSULE?

Common side effects may include headache, nausea, diarrhea, indigestion, joint pain, muscle pain, dizziness, rash, nosebleeds, drowsiness, and sleeplessness. Serious but rare side effects like severe muscle pain (myopathy or rhabdomyolysis) require immediate medical consultation. This medicine can also increase bleeding tendency.

Is CLAVILIP 10 MG CAPSULE safe during pregnancy or breastfeeding?

CLAVILIP 10 MG CAPSULE is generally contraindicated during pregnancy as components of this medicine, particularly Atorvastatin, can cause harm to unborn babies (pregnancy category X drug). It is also not recommended for use by lactating mothers, as the components may pass into breastmilk.

Can CLAVILIP 10 MG CAPSULE be taken with other medications?

CLAVILIP 10 MG CAPSULE can interact with various medications. Inform your doctor about all medicines, herbal preparations, and supplements you are currently taking. Notable interactions include:

• Other cholesterol-lowering medicines (e.g., fibrates, niacin): May increase the risk of muscle problems.
• Blood thinners (e.g., warfarin): May increase the risk of bleeding.
• Certain antibiotics (e.g., clarithromycin, azithromycin) and antifungals (e.g., itraconazole, fluconazole): Can increase the levels of atorvastatin, increasing the risk of side effects.
• Proton pump inhibitors (e.g., omeprazole, esomeprazole): Can decrease the action of clopidogrel.
• NSAIDs (pain relievers): May increase the risk of stomach or bowel bleeding.
• Grapefruit juice: Consumption of excessive grapefruit juice (more than 1.2 liters/day) should be avoided as it can increase the blood level of atorvastatin.

What precautions should be taken while using CLAVILIP 10 MG CAPSULE?

Before taking this medicine, inform your doctor if you have liver or kidney disease, bleeding disorders (such as peptic ulcer or brain hemorrhage), diabetes, or lung diseases. Alcohol consumption should be avoided as it can worsen liver conditions or cause stomach bleeding. If you have any scheduled surgery or dental procedures, inform your doctor, as this medicine may need to be stopped a few days prior to reduce the risk of bleeding. Be careful while performing activities that might cause injury, due to an increased risk of bleeding.

What happens if a dose of CLAVILIP 10 MG CAPSULE is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should CLAVILIP 10 MG CAPSULE be stored?

Store CLAVILIP 10 MG CAPSULE below 25°C or 30°C in a clean, dry place, protected from moisture, sunlight, and heat. Keep the medicine out of sight and reach of children and pets. Do not use the medicine after its expiry date.