ALDACTONE 50 MG TABLET

Name

• Generic Name: Spironolactone
• Brand Name: Aldactone

Composition

• Active Ingredient: Spironolactone 50 mg per tablet

Uses

Aldactone is a potassium-sparing diuretic primarily used for:

• Management of edema associated with congestive heart failure, cirrhosis of the liver, and nephrotic syndrome
• Treatment of primary hyperaldosteronism
• Hypertension (as adjunct therapy)
• Management of hypokalemia
• Treatment of hirsutism in females
• Polycystic ovary syndrome (PCOS) (off-label use)

Dosage and Administration

• Edema in adults: 100 mg daily, administered in either single or divided doses; may be adjusted from 25 mg to 200 mg per day based on response
• Hypertension: 50–100 mg daily, adjusted as necessary
• Primary hyperaldosteronism: 100–400 mg daily, as directed by physician
• Administration: Take with or after food to reduce gastrointestinal discomfort

Side Effects

Common:

• Hyperkalemia (high potassium levels)
• Nausea, vomiting
• Dizziness, headache
• Gynecomastia (breast enlargement in males)
• Menstrual irregularities

Serious:

• Severe hyperkalemia (potentially life-threatening)
• Allergic reactions (rash, itching, swelling)
• Renal impairment
• Severe hyponatremia (low sodium)

Precautions

• Monitor serum potassium and renal function regularly
• Not recommended for patients with anuria, acute renal insufficiency, or significant renal impairment
• Use caution in patients with hepatic dysfunction
• Avoid potassium supplements and other potassium-sparing diuretics
• May interact with ACE inhibitors, ARBs, NSAIDs, digoxin, and lithium

Storage

• Store below 25°C (77°F)
• Keep in a dry place, protected from light and moisture
• Keep out of reach of children

What is Aldactone 50 mg used for?

Aldactone (spironolactone) is a potassium-sparing diuretic used to treat conditions such as high blood pressure (hypertension), heart failure, edema (fluid retention), and certain cases of hyperaldosteronism. It may also be prescribed for hormonal acne or conditions like polycystic ovary syndrome (PCOS).

How does Aldactone work?

Aldactone works by blocking the action of the hormone aldosterone, causing the kidneys to remove excess salt and water from the body while retaining potassium. This helps reduce blood pressure and fluid buildup.

What is the usual dosage for Aldactone 50 mg?

The dosage depends on the condition being treated. For adults, typical starting doses range from 25 to 100 mg daily, either as a single dose or divided into two doses. Your doctor will determine the best dose for you based on your specific needs.

What are the possible side effects of Aldactone?

Common side effects include increased urination, dizziness, headache, nausea, breast tenderness or enlargement, and menstrual irregularities. Rare but serious side effects include high potassium levels (hyperkalemia), severe allergic reactions, or kidney problems.

Is Aldactone safe during pregnancy or breastfeeding?

Aldactone is generally not recommended during pregnancy, especially in the first trimester, due to potential risks to the fetus. While small amounts pass into breast milk, the effects on a nursing infant are not fully known; consult your doctor before use if you are pregnant or breastfeeding.

Can Aldactone be taken with other medications?

Aldactone can interact with other medications, especially those that increase potassium levels (like certain blood pressure drugs and potassium supplements), lithium, digoxin, or NSAIDs. Always inform your doctor about all medicines and supplements you are taking.

What precautions should be taken while using Aldactone?

Regular blood tests may be needed to monitor potassium and kidney function. Avoid potassium-rich foods or supplements unless advised by your doctor. Tell your doctor if you have kidney or liver problems, or if you experience muscle weakness, irregular heartbeat, or severe fatigue.

What should I do if I miss a dose of Aldactone?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose—do not double up. Continue with your regular dosing schedule.

How should Aldactone be stored?

Store Aldactone tablets at room temperature, away from moisture, heat, and direct light. Keep the medication out of reach of children and pets.