Mac Rabonic Dsr Capsules( 15 Cap)

MAC RABONIK DSR CAPSULES

MAC RABONIK DSR CAPSULES is a combination medication manufactured by Eris Lifesciences Limited, designed to effectively manage various acid-related gastrointestinal conditions.

• Name:

  • Brand Name: MAC RABONIK DSR CAPSULES
  • Common Name: Rabeprazole and Domperidone Capsules

• Composition: Each capsule typically contains:

  • Rabeprazole (40 mg): A proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach.
  • Domperidone (30 mg): A prokinetic agent and dopamine antagonist that helps increase the movement of the stomach and intestines, facilitating the easy passage of food and gas, and also helps control nausea and vomiting.

• Uses: MAC RABONIK DSR CAPSULES are primarily prescribed for the treatment and management of:

  • Gastroesophageal Reflux Disease (GERD) (acid reflux), especially in patients who have not responded adequately to rabeprazole alone.
  • Peptic Ulcer Disease, including gastric and duodenal ulcers.
  • Erosive Esophagitis, which is the inflammation and damage to the esophagus caused by stomach acid.
  • Zollinger-Ellison Syndrome, a condition characterized by excessive stomach acid production due to a pancreatic tumor.
  • Symptoms such as heartburn, stomach pain, irritation, indigestion, and discomfort related to acidity.
  • May also be used to manage nausea and vomiting.

• Dosage and Administration:

  • This medicine should be taken without food, preferably on an empty stomach, usually in the morning.
  • Swallow the capsule whole with a glass of water. Do not crush, chew, or break the capsule.
  • The dose and duration of treatment will be determined by a doctor based on the individual's condition and response to the medication.
  • It is important to continue taking the medicine for the entire duration recommended by the doctor to prevent symptoms from returning or worsening.

• Side Effects: Common side effects may include:

  • Diarrhea, stomach pain, abdominal pain, flatulence, constipation
  • Headache, dizziness
  • Nausea, vomiting, dry mouth
  • Weakness
  • Cough, sore throat, runny nose, back pain

  Serious side effects, though less common, require immediate medical attention:

  • Severe allergic reactions (e.g., sudden wheezing, swelling of the face or body, rash, difficulty swallowing)
  • Symptoms of liver problems (e.g., yellow skin, dark urine, unusual tiredness)
  • Severe skin reactions (e.g., reddening of skin with blisters or peeling, Stevens-Johnson syndrome)
  • Seizures
  • Watery diarrhea with fever or black/dark stools
  • Long-term use may lead to reduced absorption of vitamin B12, low magnesium levels (hypomagnesaemia), and an increased risk of bone fractures (osteoporosis).

• Precautions:

  • Inform your doctor if you have any existing liver, kidney, or heart problems.
  • Caution is advised in elderly patients, as they may be at increased risk of hypomagnesaemia and bone fractures with long-term use.
  • Not recommended for use in children under 12 to 18 years, pregnant, or breastfeeding women unless specifically advised by a doctor after weighing potential benefits and risks.
  • Avoid driving or operating heavy machinery if you experience dizziness, sleepiness, or blurred vision.
  • This medicine may interact with blood thinners, antifungals, anti-HIV drugs (e.g., ritonavir, atazanavir), iron supplements, and certain anti-cancer medications. Inform your doctor about all other medicines you are taking.
  • Prolonged use may mask symptoms of gastric cancer; report any severe stomach pain or blood in stool to your doctor.
  • Avoid alcohol and smoking as they can aggravate acid reflux symptoms.
  • Certain lifestyle modifications, such as avoiding spicy/fatty foods, chocolate, caffeine, and carbonated beverages, eating smaller, more frequent meals, and maintaining a healthy weight, can help manage GERD symptoms.

• Storage:

  • Store MAC RABONIK DSR CAPSULES in a cool and dry place, away from direct sunlight.
  • Keep out of the reach of children.
  • Do not use the medicine beyond its expiry date.

MAC RABONIC DSR CAPSULES: Frequently Asked Questions

MAC RABONIC DSR CAPSULES are a combination medication containing Rabeprazole sodium (a proton pump inhibitor) and Domperidone (a dopamine antagonist and prokinetic agent). This medicine is used to treat various digestive issues related to excess stomach acid and impaired gut motility.

What are MAC RABONIC DSR CAPSULES used for?

MAC RABONIC DSR CAPSULES are primarily used to treat gastroesophageal reflux disease (GERD), also known as acid reflux, which causes symptoms like heartburn, stomach pain, and irritation. It also helps in treating conditions such as peptic ulcers (gastric and duodenal ulcers), Zollinger-Ellison syndrome (a condition with excessive acid production), non-ulcer dyspepsia, NSAID-induced dyspepsia, and erosive esophagitis (inflammation and damage to the esophagus due to stomach acid). The medicine can also relieve symptoms like nausea, vomiting, stomach fullness, bloating, and gas.

How do MAC RABONIC DSR CAPSULES work?

This medicine combines two active ingredients: Rabeprazole and Domperidone.

• Rabeprazole sodium is a proton pump inhibitor (PPI). It works by blocking the action of an enzyme called the gastric proton pump in the stomach lining, which is responsible for producing stomach acid. By reducing acid production, it helps heal damage to the esophagus and prevents further irritation.
• Domperidone is a prokinetic agent that acts on the upper digestive tract. It increases the movements and contractions of the stomach and intestines, facilitating the easy passage of food through the stomach. It also blocks certain dopamine receptors in the digestive system and brain, which helps reduce nausea and vomiting.

What is the usual dosage for MAC RABONIC DSR CAPSULES?

The recommended adult oral dosage is typically one capsule once daily, or as directed by your physician. Some sources also suggest it can be given twice a day. It should be taken preferably before meals (30-60 minutes prior) for optimal effectiveness and should be swallowed whole with liquid, not chewed or crushed. The exact dose and duration will depend on your medical condition and response to the medication.

What are the possible side effects of MAC RABONIC DSR CAPSULES?

Common side effects may include dry mouth, stomach pain, diarrhea, headache, flatulence (gas), nausea, vomiting, dizziness, and weakness. Most of these side effects are usually temporary and resolve over time. However, if they persist or worsen, it's advised to consult your doctor. In rare cases, domperidone has been associated with an increased risk of heart rhythm disturbances.

Is it safe during pregnancy or breastfeeding?

MAC RABONIC DSR CAPSULES are generally not recommended during pregnancy or breastfeeding. Rabeprazole is contraindicated in pregnancy and lactation. While there are limited post-marketing data on domperidone in pregnant women, and studies show it enters breast milk, it is not known whether this is harmful to the newborn. Your doctor will weigh the benefits against the risks before prescribing it if you are pregnant or breastfeeding.

Can it be taken with other medications?

MAC RABONIC DSR CAPSULES can interact with several medications. It is important to inform your doctor about all the medicines, supplements, or herbal products you are currently taking to prevent possible interactions.

Some notable interactions include:

• Antifungal drugs (e.g., ketoconazole, itraconazole): Absorption may be reduced.
• Antibiotics (e.g., clarithromycin, erythromycin): May alter the medication's effectiveness or increase rabeprazole levels.
• Blood thinners (e.g., warfarin, clopidogrel): May increase the risk of bleeding.
• Anti-HIV drugs (e.g., atazanavir): Co-administration with PPIs like rabeprazole is not recommended.
• Methotrexate: Temporary withdrawal of the PPI may be considered with high-dose methotrexate.
• QT-prolonging drugs: Domperidone is contraindicated with such drugs, except apomorphine if benefits outweigh risks.
• Potent CYP3A4 inhibitors: Co-administration with potent CYP3A4 inhibitors is contraindicated.

What precautions should be taken?

Inform your doctor if you have kidney or liver disease, a stomach tumor, a history of gastrointestinal bleeding or intestinal obstruction, osteoporosis, or heart problems (especially a prolonged QT interval, significant electrolyte disturbances, or congestive heart failure). Long-term use of this medicine may lead to low magnesium and vitamin B12 levels, and an increased risk of bone fractures. Avoid alcohol consumption as it can increase stomach acid production and worsen side effects like drowsiness. This medicine may cause dizziness, so caution is advised while driving or operating machinery until you know how it affects you.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should it be stored?

MAC RABONIC DSR CAPSULES should be stored in a cool and dry place, protected from heat, light, and moisture. Keep the medicine in its original container, tightly closed, and out of reach of children.