Tenglyn 20 Mg Tablet (15 Tab)

TENGLYN 20 MG TABLET

TENGLYN 20 MG TABLET, manufactured by Zydus Cadila, is an oral anti-diabetic medication used to manage elevated blood sugar levels in adults with Type 2 Diabetes Mellitus.

Composition

TENGLYN 20 MG TABLET contains Teneligliptin 20 mg as its active ingredient. Teneligliptin belongs to a class of medicines called dipeptidyl peptidase-4 (DPP-4) inhibitors.

Uses

TENGLYN 20 MG TABLET is primarily prescribed for the treatment of Type 2 Diabetes Mellitus. It is used alone or in combination with other anti-diabetic drugs when diet and exercise alone are insufficient to control blood sugar levels. This medication works by promoting insulin secretion from the pancreas and regulating blood sugar post-meal by controlling glucagon secretion, thereby lowering blood glucose levels. Effective blood sugar control helps prevent long-term complications of diabetes such as kidney damage, nerve damage, eye damage, and diabetic foot ulcers.

Dosage and Administration

The usual adult dosage is 20 mg of teneligliptin administered orally once daily. If efficacy is insufficient, the dose may be increased up to 40 mg once daily, under close medical supervision. It can be taken with or without food, but taking it after meals may help minimize stomach upset. The tablet should be swallowed whole with a glass of water and not crushed or chewed. It is important to take the medicine at the same time each day and not to discontinue treatment without consulting a doctor.

Side Effects

Common side effects include:

• Headache
• Low blood glucose levels (hypoglycemia), especially when combined with other anti-diabetic medications like insulin or sulfonylureas.
• Upper respiratory tract infection
• Nasopharyngitis (common cold)
• Dizziness
• Constipation
• Diarrhea
• Nausea and vomiting
• Fever Serious side effects, though rare, can include acute pancreatitis and severe allergic reactions such as skin swelling or rash.

Precautions

• Allergy: Do not take TENGLYN 20 MG TABLET if you are allergic to teneligliptin or any of its components.
• Diabetes Type: It is not suitable for Type 1 Diabetes Mellitus or diabetic ketoacidosis.
• Medical Conditions: Inform your doctor if you have liver or kidney problems, heart problems (including irregular heartbeat or QT prolongation), acute pancreatitis, adrenal insufficiency, malnutrition, or a history of abdominal surgery or bowel obstruction.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding. Its safety in these situations has not been established.
• Alcohol: Limit alcohol consumption as it can increase the risk of low blood sugar.
• Driving and Machinery: This medicine may cause dizziness or low blood sugar, which can impair your ability to drive or operate machinery.
• Children: The safety and efficacy in children have not been established.
• Drug Interactions: Inform your doctor about all other medications, supplements, and herbal products you are taking, especially other anti-diabetic agents, beta-blockers, salicylic acid, certain antidepressants, adrenaline, and some antifungal or antibiotic medications.

Storage

Store TENGLYN 20 MG TABLET in a cool and dry place, protected from sunlight and moisture. The recommended storage temperature is typically between 10°C to 30°C. Keep it out of sight and reach of children.

TENGLYN 20 MG TABLET (15 TAB) is an oral medication containing Teneligliptin, primarily used in the management of Type 2 Diabetes Mellitus. It works alongside diet and exercise to help control blood sugar levels.

What is TENGLYN 20 MG TABLET used for?

TENGLYN 20 MG TABLET is used to treat Type 2 Diabetes Mellitus in adults. It helps manage and control elevated blood sugar levels, especially when diet and exercise alone are not sufficient. By regulating blood sugar, it aids in reducing the risk of serious diabetes-related complications such as kidney damage, vision impairment, nerve problems, and limb amputation.

How does TENGLYN 20 MG TABLET work?

This medicine contains Teneligliptin, which is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by blocking the action of the DPP-4 enzyme, which is responsible for inactivating incretin hormones (like GLP-1 and GIP). By inhibiting DPP-4, Teneligliptin increases the levels of active incretin hormones in the body. These hormones then stimulate the pancreas to produce more insulin after meals and decrease the release of glucagon, a hormone that raises blood sugar. This dual action helps to lower both fasting and post-meal blood glucose levels.

What is the usual dosage for TENGLYN 20 MG TABLET?

The usual adult dosage is 20 mg taken orally once daily. If the effect is not sufficient, your doctor may increase the dose up to 40 mg once daily, while closely monitoring your condition. It is important to take the tablet at the same time each day as prescribed by your doctor, and it can be taken with or without food.

What are the possible side effects of TENGLYN 20 MG TABLET?

Common side effects can include hypoglycemia (low blood sugar), which may manifest as lightheadedness, sweating, dizziness, headache, or shakiness. Other common side effects are constipation, diarrhea, nausea, vomiting, upper respiratory tract infection, and nasopharyngitis (common cold symptoms). More serious, but less common, side effects can include acute pancreatitis and severe allergic reactions.

Is TENGLYN 20 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: TENGLYN 20 MG TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, and only if prescribed by a physician. Its safety during pregnancy has not been definitively established, and animal studies have shown harmful effects on the developing baby. Breastfeeding: Breastfeeding should be stopped while taking TENGLYN 20 MG TABLET. It is considered probably unsafe during breastfeeding, as limited human data suggests the drug may pass into breast milk and could harm the baby.

Can TENGLYN 20 MG TABLET be taken with other medications?

Yes, TENGLYN 20 MG TABLET can be taken alone or in combination with other anti-diabetic medications. However, caution is advised when combining it with other diabetes medications or insulin due to an increased risk of hypoglycemia. It may interact with certain medications such as beta-blockers (for high blood pressure), salicylic acid, some antidepressants, adrenaline, steroids, thyroid hormones, antifungals (like ketoconazole), and certain antibiotics (like rifampicin). Always inform your doctor about all other medications, supplements, and herbal products you are taking to avoid potential interactions.

What precautions should be taken while using TENGLYN 20 MG TABLET?

TENGLYN 20 MG TABLET is not suitable for individuals with Type 1 diabetes mellitus or diabetic ketoacidosis. Inform your doctor if you have a history of kidney disease, liver problems, heart issues (such as congestive heart failure, irregular heart rhythm, or QT prolongation), or pancreas problems (like pancreatitis). Excessive alcohol consumption should be avoided as it can increase the risk of low blood sugar and pancreatitis. If you experience dizziness due to low blood sugar, avoid driving or operating machinery. Regular monitoring of blood sugar levels, along with maintaining a proper diet and exercise regimen, is crucial while on this medication.

What happens if a dose of TENGLYN 20 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can lead to fluctuations in blood sugar.

How should TENGLYN 20 MG TABLET be stored?

TENGLYN 20 MG TABLET should be stored in a cool and dry place, away from direct sunlight. Keep it out of sight and reach of children. The medication should be stored below 30°C.