Oflin O Tab

OFLIN O TABLET

OFLIN O TABLET is a combination antibiotic medication manufactured by Zydus Healthcare Ltd. (Fortiza Div).

• Composition:

  • Ofloxacin (200 mg)
  • Ornidazole (500 mg)

• Uses: OFLIN O TABLET is prescribed to treat a broad spectrum of bacterial and parasitic infections. It is effective against:

  • Gastrointestinal Infections: Diarrhea of mixed infections, dysentery, gastroenteritis.
  • Urinary Tract Infections (UTIs).
  • Respiratory Infections: Including bronchitis and pneumonia.
  • Skin and Soft Tissue Infections.
  • Sexually Transmitted Infections (e.g., gonorrhea).
  • Gynecological Infections: Vaginal infections, bacterial vaginosis, pelvic inflammatory disease, endometritis, puerperal sepsis, septic abortion, certain genital infections.
  • Other Infections: Bacterial infections of the peritoneum, eye and ear infections, protozoan infections, intra-abdominal infections, infections during surgical procedures, meningitis, septicemia.

• Dosage and Administration:

  • Take OFLIN O TABLET exactly as prescribed by your doctor.
  • It can be taken with or without food, though taking it with food may help reduce stomach discomfort. Some sources suggest taking it on an empty stomach (1 hour before or 2 hours after meals).
  • Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
  • Typically, the medicine is taken twice daily.
  • Complete the full course of treatment even if your symptoms improve to prevent the infection from returning and becoming harder to treat.
  • Do not exceed the prescribed dose.

• Side Effects:

  • Common Side Effects: Nausea, vomiting, abdominal pain, headache, dizziness, insomnia/difficulty falling asleep, decreased appetite, changes in taste, mild skin rash, itching, stomach discomfort, fungal infections.
  • Serious Side Effects: Painful urination, black or tarry stools, shaking of the hands or feet, difficulty in breathing, red spots on the skin, and an increased risk of tendon rupture or tendinitis, particularly in older patients. Overdose symptoms can include confusion, convulsive seizures, mucosal erosions, and impairment of consciousness.

• Precautions:

  • Avoid OFLIN O TABLET if you are allergic to its components, have a history of tendon swelling or tearing with quinolone antibiotics, or suffer from myasthenia gravis, as it may worsen muscle weakness.
  • Consult your doctor before use if you have epilepsy (as it may trigger seizures), low potassium levels, nervous or muscle problems, head injury or brain tumor, diabetes, rheumatoid arthritis, multiple sclerosis, or heart, kidney, or liver problems.
  • Not recommended for children under 16 or 18 years of age.
  • Avoid alcohol consumption during treatment and for 48 hours after the last dose, as it can cause increased dizziness and a potential disulfiram-like reaction (severe nausea, vomiting, etc.).
  • OFLIN O TABLET may cause dizziness and drowsiness; avoid driving or operating machinery until you know how the medicine affects you.
  • Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding, as its use during these periods may be unsafe.
  • Be aware of potential photosensitivity; the medication may increase sensitivity to sunlight.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Maintain storage temperatures between 10ºC to 25ºC or below 30ºC.
  • Keep out of sight and reach of children.
  • Protect from light and moisture.

OFLIN O TAB, manufactured by ZYDUS HEALTHCARE - FORTIZA DIV, is a combination antibiotic medication used to treat various bacterial and parasitic infections. It contains Ofloxacin (200 mg) and Ornidazole (500 mg).

Here are some frequently asked questions about OFLIN O TAB:

1. What is OFLIN O TAB used for?

OFLIN O TAB is used to treat a wide range of bacterial and parasitic infections. These include gastrointestinal infections like diarrhea, dysentery, and gastroenteritis, as well as urinary tract infections, respiratory infections (such as pneumonia, bronchitis, and sinusitis), eye and ear infections, skin and soft tissue infections, and certain sexually transmitted and gynecological infections. It may also be used as a preventive measure during surgical procedures.

2. How does OFLIN O TAB work?

OFLIN O TAB combines two active ingredients: Ofloxacin and Ornidazole. Ofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA gyrase, an enzyme crucial for bacterial DNA replication, transcription, and repair, ultimately leading to bacterial cell death. Ornidazole is a nitroimidazole antibiotic and antiprotozoal agent that disrupts the DNA structure and protein synthesis in susceptible organisms, causing cell death in anaerobic bacteria and protozoa. Together, these components work synergistically to combat infections.

3. What is the usual dosage for OFLIN O TAB?

The usual dosage of OFLIN O TAB is typically one tablet, taken twice daily, or as prescribed by your doctor. It can be taken with or without food, but taking it with food may help reduce stomach discomfort. It is often recommended to take it on an empty stomach, either 1 hour before or 2 hours after meals. Always swallow the tablet whole with a glass of water, and do not crush, chew, or break it. It is crucial to complete the full course of treatment as prescribed by your doctor, even if your symptoms improve earlier, to ensure the infection is fully eradicated and to prevent resistance.

4. What are the possible side effects of OFLIN O TAB?

Common side effects include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and difficulty falling asleep (insomnia). Other potential side effects may include mild skin rash, stomach discomfort, loss of appetite, itching, vaginal inflammation, dry mouth, and changes in taste or smell. If you experience any severe or persistent side effects, or signs of an allergic reaction (like rash, itching, swelling, or breathing difficulties), seek immediate medical attention.

5. Is OFLIN O TAB safe during pregnancy or breastfeeding?

No, OFLIN O TAB is generally not recommended and is contraindicated during pregnancy and breastfeeding. This is due to potential risks to the developing baby or infant. It is essential to consult your doctor if you are pregnant, planning to conceive, or breastfeeding, as they will assess the potential risks and benefits in your specific situation.

6. Can OFLIN O TAB be taken with other medications?

OFLIN O TAB can interact with several medications. It should be used with caution or avoided with:

• Alcohol: Strictly avoid alcohol during treatment and for 48 hours after the last dose due to a potential disulfiram-like reaction (severe nausea, vomiting, headache).
• Blood thinners (e.g., warfarin): May increase the risk of bleeding.
• Cyclosporine: May lead to increased cyclosporine levels and potential kidney problems.
• NSAIDs (e.g., ibuprofen): May heighten the risk of seizures or convulsions.
• Tricyclic antidepressants: Can increase side effects like dizziness and confusion.
• Certain heart rhythm medications: Such as quinidine, amiodarone, and sotalol, due to the risk of affecting heart rhythm.
• Antacids, dairy products, and calcium-fortified juices: These can reduce the effectiveness of OFLIN O TAB if taken at the same time. It's advisable to take the medicine a few hours before or after consuming these. Always inform your doctor about all other medications, supplements, and herbal products you are taking to avoid potential interactions.

7. What precautions should be taken while using OFLIN O TAB?

• Allergies: Do not take OFLIN O TAB if you are allergic to Ofloxacin, Ornidazole, or any quinolone or nitroimidazole antibiotics.
• Medical Conditions: Inform your doctor if you have a history of conditions such as epilepsy, low potassium levels, nervous or muscle disorders (especially myasthenia gravis), head injury, diabetes, rheumatoid arthritis, multiple sclerosis, or heart, kidney, or liver problems.
• Driving & Machinery: This medication may cause dizziness or fatigue, so exercise caution when driving or operating machinery until you know how it affects you.
• Sun Exposure: OFLIN O TAB may increase sensitivity to sunlight, so avoid prolonged exposure to direct sunlight and use protective measures.
• Tendon Problems: There is a risk of tendonitis and tendon rupture, especially in older patients and those with a history of tendon issues. Report any tendon pain, swelling, or inflammation to your doctor.

8. What happens if a dose of OFLIN O TAB is missed?

If you forget to take a dose of OFLIN O TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

9. How should OFLIN O TAB be stored?

Store OFLIN O TAB at room temperature, typically between 15-30°C (or below 30°C), in its original container. Protect it from light and moisture to maintain its effectiveness. Always keep this medicine out of the reach of children.