Zyrcold Tab

ZYRCOLD TAB by DR REDDY S LABORATORIES LTD

Name

• Brand Name: Zyrcold Tablet
• Common Name: Cetirizine and Ambroxol Tablets

Composition Zyrcold Tablet comprises two active components:

• Ambroxol (60 mg): This mucolytic agent works by reducing the viscosity of mucus and aiding expectoration, making it easier to cough up.
• Cetirizine (5 mg): A second-generation antihistamine that selectively blocks peripheral H1 receptors, thereby reducing allergic inflammation and associated symptoms.

Uses Zyrcold Tablet is primarily prescribed for the management of productive cough linked to:

• Respiratory tract allergies and infections.
• Allergic rhinitis.
• Bronchitis.
• Allergic symptoms such as sneezing, runny nose, watery eyes, itching, swelling, and congestion or stiffness.
• Thickened mucus cough and acute sore throat.

Dosage and Administration

• Take Zyrcold Tablet strictly as directed by your doctor.
• The tablet can be consumed with or without food.
• Swallow the tablet whole with water; do not crush or chew it.
• Dosage may vary based on the individual's condition and response to treatment.
• For adults and children 12 years and older, a typical starting dose is one 5mg tablet once daily. Children aged 6 to 11 years may be prescribed a lower dose, usually 2.5mg once daily.
• Never exceed the prescribed dosage without consulting a healthcare professional.

Side Effects Common side effects that may occur include:

• Nausea, Vomiting, Diarrhoea, Stomach pain.
• Dizziness, Fatigue, Sedation, Sleepiness.
• Dry mouth.
• Headache.
• Allergic reactions.

Precautions

• Pregnancy: Consult your doctor if you are pregnant, as caution is advised.
• Breastfeeding: Zyrcold Tablet is contraindicated for breastfeeding women due to the potential excretion of components into breast milk.
• Alcohol: Avoid consuming alcohol while on this medication as it may heighten drowsiness and dizziness.
• Liver Impairment: Use with caution in patients with mild to moderate liver issues; dose adjustments may be necessary.
• Kidney Disease: Exercise caution if you have kidney problems; dose adjustments might be required, especially in severe renal impairment.
• Driving and Operating Machinery: Due to potential dizziness or drowsiness, avoid driving or operating heavy machinery until you understand how the medicine affects you.
• Allergy: Inform your doctor about any known allergies to cetirizine or ambroxol.
• Children: Not recommended for children under 12 years, or under 6 years without medical consultation, due to potential severe side effects from cetirizine.
• Epilepsy: Caution is advised in patients with epilepsy, as cetirizine has been reported to potentially cause or aggravate seizures.
• Drug Interactions: Inform your doctor about all current medications, particularly Alprazolam, Codeine, Isocarboxazid, Midodrine, and Ritonavir.
• Discontinue Zyrcold Tablet at least three days before an allergy test, as it can interfere with test results.

Storage

• Store Zyrcold Tablet below 30°C in a cool, dry place. Some recommendations specify below 25°C.
• Protect the medicine from direct sunlight and moisture.
• Keep out of sight and reach of children and pets.
• Always verify the expiry date and properly discard any unused medicine after this date.

Frequently Asked Questions about ZYRCOLD TAB

What is Zyrcold Tablet used for?

Zyrcold Tablet is primarily used to manage productive cough associated with respiratory tract allergies and infections. It also helps relieve allergic symptoms such as sneezing, runny nose, watery eyes, itching, swelling, and congestion or stiffness.

How does Zyrcold Tablet work?

Zyrcold Tablet contains two active ingredients: Cetirizine and Ambroxol. Cetirizine is an antihistamine that works by blocking histamine, a chemical messenger responsible for allergic reactions in the body, thereby reducing symptoms like sneezing, runny nose, and itching. Ambroxol is a mucolytic agent that thins and loosens mucus (phlegm), making it easier to cough out.

What is the usual dosage for Zyrcold Tablet?

The dosage of Zyrcold Tablet should be taken as prescribed by your doctor, as it can vary based on your condition and response to the medication. It is generally taken once or twice a day, and can be consumed with or without food. For conditions like allergic rhinitis, a typical recommendation might be one tablet daily for seven days, with a strength of Cetirizine 5 mg + Ambroxol 60 mg.

What are the possible side effects of Zyrcold Tablet?

Common side effects of Zyrcold Tablet may include nausea, vomiting, diarrhea, stomach pain, dizziness, fatigue, and dry mouth. Other possible side effects can include sedation, headache, blurred vision, bronchospasm, tremor, or tongue discoloration. If side effects persist or worsen, consult your doctor.

Is Zyrcold Tablet safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised when taking Zyrcold Tablet if you are pregnant. It may be unsafe, as animal studies have shown harmful effects on the developing baby, although human studies are limited. Your doctor will weigh the benefits against potential risks before prescribing it.

Breastfeeding: Zyrcold Tablet is generally considered unsafe and is contraindicated for breastfeeding women. Its components can pass into breast milk and may harm the baby.

Can Zyrcold Tablet be taken with other medications?

Zyrcold Tablet can interact with certain medications. For instance, its cetirizine component can intensify the effects of sedatives like diazepam or lorazepam and muscle relaxers such as cyclobenzaprine. Ambroxol in Zyrcold can increase the penetration of some antibiotics, like amoxicillin or cefuroxime, into lung tissue, potentially enhancing their effectiveness. It may also interact with medications like Alprazolam, Codeine, Isocarboxazid, Lasmiditan, Gabapentin, and Theophylline. Always inform your doctor about all other prescribed or non-prescribed medicines, herbal remedies, and supplements you are taking.

What precautions should be taken while using Zyrcold Tablet?

It is recommended to avoid alcohol consumption while taking Zyrcold Tablet, as it may increase drowsiness and dizziness. Exercise caution when driving or operating machinery, as the medicine can cause dizziness and sleepiness. Inform your doctor if you have kidney or liver disease, as dose adjustments may be needed or the medicine may be contraindicated in severe cases. Patients with epilepsy should use it with caution, as cetirizine may cause or aggravate seizures. It is also contraindicated if you have a known hypersensitivity to ambroxol, cetirizine, or any other components in the formulation. Zyrcold Tablet is not recommended for children under 12 years of age (some sources mention under 6 years) due to the risk of severe side effects. Older patients should take this medicine under medical supervision. Additionally, if you are due for an allergy test, stop taking Zyrcold Tablet at least three days beforehand, as it can affect the test results. Inform your doctor if your cough persists for more than 14 days.

What happens if a dose of Zyrcold Tablet is missed?

If you miss a dose of Zyrcold Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should Zyrcold Tablet be stored?

Zyrcold Tablet should be stored below 30°C, or ideally below 25°C, in a cool and dry place. It should be protected from direct sunlight and moisture, and kept out of the reach of children and pets. Always check the expiry date and discard any unused medicine after this date.