Diprobate Plus Lotion 50 Ml

DIPROBATE PLUS LOTION 50 ML

Diprobate Plus Lotion is a topical medication used for the management of various inflammatory skin conditions.

• Name:

  • Brand Name: Diprobate Plus Lotion
  • Common Name: Betamethasone and Zinc Sulfate Lotion

• Composition:

  • Each 50 ML of lotion contains Betamethasone (0.05% w/v) and Zinc Sulfate (0.5% w/v).

• Uses: Diprobate Plus Lotion is prescribed to manage inflammatory skin diseases that cause itching, redness, dryness, crusting, scaling, and swelling. These conditions include:

  • Eczema (atopic dermatitis)
  • Contact dermatitis
  • Psoriasis
  • It also possesses antiseptic properties, helping to prevent microbial growth in affected areas.

• Dosage and Administration:

  • For external use only.
  • Wash hands thoroughly before and after application, unless the treatment is for the hands.
  • Clean and dry the affected area before applying the lotion.
  • Apply a thin layer of the lotion to the affected skin and gently rub it in until absorbed.
  • Typically, it is applied once or twice daily, or as directed by your physician.
  • Do not apply to broken skin, open wounds, or sensitive areas like the eyes, mouth, nose, or genitals. If accidental contact occurs, rinse thoroughly with water.

• Side Effects: Common side effects may include:

  • Redness at the application site
  • Itching or skin irritation
  • Inflamed hair follicles (folliculitis)
  • Blistering
  • Burning or stinging sensation

  Serious side effects are rare but can include:

  • Allergic reactions (e.g., severe rash, swelling, dizziness, trouble breathing)
  • Skin thinning (with prolonged use)

• Precautions:

  • Inform your doctor about any history of diabetes, liver disease, Cushing's syndrome, adrenal gland problems, poor blood circulation, or a compromised immune system.
  • Avoid using on the face, groin, or underarms unless specifically directed by a doctor, especially for prolonged periods, to prevent skin thinning.
  • Do not cover the treated area with airtight dressings (e.g., bandages) unless advised by your doctor.
  • Not recommended for fungal or viral skin infections, acne, or rosacea.
  • Pregnancy and Breastfeeding: Use with caution and only if recommended by a doctor, who will assess the benefits against potential risks.
  • Children: Use under medical supervision. It is not recommended for children under 1 year of age. Use with caution for more than 5 days on children's skin or face.
  • Do not use if you are allergic to Betamethasone, Zinc Sulfate, or any other ingredients in the lotion.

• Storage:

  • Store below 30°C.
  • Keep in its original packaging, away from moisture and direct sunlight.
  • Keep out of sight and reach of children.

What is Diprobate Plus Lotion used for?

Diprobate Plus Lotion is primarily used to manage various inflammatory skin conditions such as eczema, contact dermatitis, and psoriasis. It helps to relieve symptoms like redness, swelling, itching, dryness, crusting, and scaling. It can also be used for skin infections or dermatitis complicated by bacterial or fungal infections.

How does Diprobate Plus Lotion work?

Diprobate Plus Lotion is a combination of two active ingredients: Betamethasone and Zinc Sulfate (or Salicylic Acid in some formulations). Betamethasone is a corticosteroid that works by blocking the production of chemical messengers (prostaglandins) that cause the skin to become red, swollen, and itchy, thereby reducing inflammation and immune response. Zinc Sulfate acts as an astringent and antiseptic, helping to prevent microbial growth and promote tissue health. If Salicylic Acid is present, it acts as a keratolytic agent to exfoliate dead skin cells, reducing scaling and aiding in corticosteroid penetration.

How should I apply Diprobate Plus Lotion? What is the usual dosage?

Diprobate Plus Lotion is for external (topical) use only. Before application, clean and dry the affected area. Apply a thin layer of the lotion to the affected skin and gently massage it in until absorbed. Wash your hands thoroughly before and after applying the lotion, unless the treatment is for your hands. The typical dosage is usually 1-2 times daily, or as directed by your doctor. It is important to use this medicine exactly as prescribed by your doctor and not for longer than recommended, as prolonged or excessive use can lead to side effects. Do not cover the treated area with bandages or airtight dressings unless instructed by your doctor.

What are the possible side effects of Diprobate Plus Lotion?

Common side effects include skin irritation, redness, burning, stinging, itching, or dryness at the application site. Other possible local side effects include inflamed hair follicles (folliculitis), blistering, and excessive drying or peeling of the skin. With prolonged use or application over large skin areas, systemic side effects can occur due to absorption into the bloodstream. These include HPA axis suppression (affecting hormone levels), elevated blood sugar levels (hyperglycemia), weakening of bones (osteoporosis), Cushing's Syndrome, skin thinning/discoloration, increased hair growth, and visible veins. If any severe or persistent side effects occur, or if you experience signs of an allergic reaction like rash, swelling, or difficulty breathing, discontinue use and seek medical advice.

Is Diprobate Plus Lotion safe during pregnancy or breastfeeding?

Diprobate Plus Lotion should be used with caution during pregnancy and breastfeeding, and only if recommended by a doctor after evaluating the benefits and risks. Limited human data suggests it may be safe during breastfeeding and does not represent a significant risk to the baby if prescribed by an expert, but it should not be applied to the breasts to avoid accidental ingestion by the infant. Animal studies have shown harmful effects on the developing baby with betamethasone, so consult your doctor.

Can it be taken with other medications?

There are no known interactions with alcohol. However, it is always best to inform your doctor about all medications, including over-the-counter drugs, herbal supplements, and other topical products you are using, to avoid potential interactions. Some sources suggest potential interactions with medicines like amlodipine, mifepristone, warfarin, insulin, and certain vaccines. If you are using other topical medications, it's generally advised to wait at least 30 minutes before applying Diprobate Plus Lotion.

What precautions should be taken?

Avoid applying Diprobate Plus Lotion near the eyes, mouth, nose, or genital area. If accidental contact occurs, rinse thoroughly with water. Do not use it on broken or infected skin unless specifically directed by a doctor. Prolonged use, especially on the face, should be avoided as it can cause skin thinning. It is generally not recommended for use in children below 13 years of age due to the risk of growth retardation. Inform your doctor if you have a history of liver disease, diabetes, adrenal gland problems, poor blood circulation, or immune system problems. Avoid covering the treated area with bandages unless advised by your healthcare provider.

What happens if a dose is missed?

If you miss a dose of Diprobate Plus Lotion, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular application schedule. Do not apply a double dose to make up for the missed one.

How should it be stored?

Diprobate Plus Lotion should be stored in its original packaging, in a cool and dry place, away from direct sunlight and heat. Keep the bottle tightly closed when not in use and keep it out of the sight and reach of children and pets. Follow the specific storage instructions mentioned on the pack or label.