Tynept Od Tablet

Here is a detailed product description for TYNEPT OD TABLET by INTAS PHARMACEUTICALS LTD:

Name

• Brand Name: Tynept OD Tablet, Tynept OD Tablet ER
• Common Name: Tianeptine (Extended Release)

Composition

• Active Ingredient: Tianeptine (typically 37.5 mg)

Uses Tynept OD Tablet is an antidepressant primarily prescribed for the treatment of depression in adults. It is also used to manage neurotic or reactive states of depression, anxiodepressive states (including those with digestive complaints), and anxio-depressive states observed in individuals undergoing alcohol detoxification. Some sources also mention its use for anxiety, bed-wetting, obsessive-compulsive disorder, insomnia, and neuropathic pain.

Dosage and Administration Tynept OD Tablet should be taken as advised by a doctor. It is typically swallowed whole with a glass of water and should not be crushed or chewed. To ensure better efficacy, it's recommended to take it at a fixed time each day, with or without food, preferably before bedtime as it can cause drowsiness. The dose and duration of treatment are determined by the physician based on the patient's age, medical condition, and body weight. Abrupt discontinuation of the medicine should be avoided; the dose should be gradually reduced under medical supervision to prevent withdrawal symptoms. It is not recommended for individuals under 18 years of age.

Side Effects

• Common Side Effects: Drowsiness, dizziness, fatigue, headache, dry mouth, sore throat, loss of appetite, feeling unwell, irritation, diarrhoea, constipation, increased heart rate, blurred vision, difficulty in urination, orthostatic hypotension (sudden lowering of blood pressure upon standing), and weight gain.
• Serious Side Effects: Rare but serious side effects can include suicidal thoughts (especially in patients under 18), and symptoms of overdose such as hallucinations, difficulty breathing, irregular heartbeat, fits, and loss of consciousness.

Precautions

• Inform your doctor if you have allergies to Tianeptine or any other components of the medicine.
• Not recommended during pregnancy or breastfeeding.
• Use with caution in patients with liver or kidney diseases, with dose adjustments possibly necessary.
• Avoid alcohol consumption as it can increase drowsiness and the risk of adverse effects.
• May cause drowsiness or decreased alertness; avoid driving or operating heavy machinery until you know how the medicine affects you.
• Monitor for suicidal thoughts, especially at the start of treatment.
• Inform your doctor about all other medications you are taking, especially other antidepressants (e.g., MAOIs like phenelzine, selegiline, tranylcypromine, isocarboxazid, mianserin), antipsychotics, antihypertensives, and antibiotics, as interactions may occur.
• Long-term use or higher doses may increase the risk of habit-forming tendency and dependence.

Storage Keep this medicine out of the sight and reach of children and pets. Store below 25°C.

Frequently Asked Questions About TYNEPT OD TABLET

TYNEPT OD TABLET, manufactured by Intas Pharmaceuticals Ltd, contains the active ingredient Tianeptine. It is an antidepressant used in several countries, though it is not approved for medical use in the United States.

What is TYNEPT OD TABLET used for?

TYNEPT OD TABLET is primarily used to manage depression. It is prescribed for neurotic or reactive states of depression, anxiety-depressive states, including those with digestive problems, and anxiety-depressive states experienced by alcoholics undergoing detoxification. It may also be used for anxiety and irritable bowel syndrome in some regions.

How does TYNEPT OD TABLET work?

TYNEPT OD TABLET works by affecting certain chemical messengers in the brain, such as serotonin and norepinephrine, to help regulate mood and reduce symptoms of depression and anxiety. Unlike most conventional antidepressants that increase serotonin availability, tianeptine is thought to influence glutamate and opioid receptors, which can lead to antidepressant and anxiolytic effects. It increases the levels of these chemical messengers, helping to stabilize and enhance mood.

What is the usual dosage for TYNEPT OD TABLET?

The dosage for TYNEPT OD TABLET should be strictly as advised by your doctor. While immediate-release tianeptine is often prescribed as 12.5 mg three times daily, TYNEPT OD TABLET (37.5 mg) is an extended-release (OD for "Once Daily") formulation, usually taken once daily. It is often recommended to take this tablet before bedtime due to its potential to cause drowsiness. Your physician will determine the correct dose and duration based on your age, condition, and body weight.

What are the possible side effects of TYNEPT OD TABLET?

Common side effects may include drowsiness, dizziness, fatigue, headache, dry mouth, constipation, nausea, abdominal pain, loss of appetite, insomnia, and nightmares. More serious, though rare, side effects can include liver damage and cardiovascular issues like irregular heartbeats. Long-term use, especially at high doses, carries a risk of dependence and withdrawal symptoms similar to those of opioid withdrawal.

Is TYNEPT OD TABLET safe during pregnancy or breastfeeding?

TYNEPT OD TABLET is generally not recommended for use during pregnancy or breastfeeding. Tianeptine is possibly unsafe during pregnancy as it can cause the infant to be born with neonatal abstinence syndrome (withdrawal symptoms). There is insufficient reliable information about its safety during breastfeeding, but similar drugs can pass into breast milk.

Can TYNEPT OD TABLET be taken with other medications?

You should inform your doctor about all other medications, supplements, and herbal products you are taking. TYNEPT OD TABLET should not be taken concurrently with Monoamine Oxidase Inhibitors (MAOIs), and there should be a gap of at least two weeks after discontinuing MAOIs before starting tianeptine. It can interact with sedative medications, increasing drowsiness and slowed breathing. Alcohol should be avoided as it can increase side effects. Caution is also advised with other antidepressants, antipsychotics, certain antibiotics (like linezolid), and blood thinners like warfarin.

What precautions should be taken while taking TYNEPT OD TABLET?

Inform your doctor if you have kidney or liver disease, a history of substance abuse, seizures, schizophrenia, diabetes, or heart disease. Avoid driving or operating heavy machinery if you experience drowsiness or decreased alertness. If surgery requiring general anesthesia is planned, you must inform your doctor that you are taking TYNEPT OD TABLET. Do not stop taking the medicine abruptly, as this can lead to withdrawal symptoms; gradual discontinuation under medical supervision is necessary.

What happens if a dose of TYNEPT OD TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should TYNEPT OD TABLET be stored?

TYNEPT OD TABLET should be stored below 30°C. Keep the container tightly closed and protect it from humidity.