Glempa Lm Er 10/5/1000mg Tab

GLEMPA LM ER 10/5/1000MG Tablet

Name

• Brand Name: GLEMPA LM ER 10/5/1000MG TAB.
• Manufacturer: Glenmark Pharmaceuticals Ltd. (Zesta Division)

Composition GLEMPA LM ER 10/5/1000MG Tablet is a fixed-dose combination medication containing three active ingredients:

• Empagliflozin (10 mg)
• Linagliptin (5 mg)
• Metformin (1000 mg)

Uses This medication is prescribed for adults with Type 2 Diabetes Mellitus. It is used to manage blood sugar levels, especially when diet and exercise alone, or treatment with single or dual therapies, do not provide adequate glycemic control. Additionally, it can help reduce the risk of cardiovascular death in diabetic patients with established heart disease and may lower hospitalization rates for heart failure.

Dosage and Administration GLEMPA LM ER should be taken exactly as prescribed by your doctor. It can be taken with or without food, but taking it with meals may help avoid stomach upset. For best results, it is recommended to take it at the same time each day. Do not crush, break, or chew the tablet, and do not discontinue the medication suddenly without consulting your doctor, as this can lead to serious complications.

Side Effects Common side effects may include:

• Urinary tract infections (UTIs)
• Nasopharyngitis
• Upper respiratory tract infections
• Increased urination frequency
• Nausea
• Diarrhea
• Genital yeast infections

Precautions

• Contraindications: This medicine is not recommended for individuals with Type 1 diabetes, diabetic ketoacidosis, severe kidney impairment, or metabolic acidosis (such as lactic acidosis).
• Medical Conditions: Inform your doctor if you have kidney or liver problems, a urinary tract infection, or if you are over 75 years of age.
• Pregnancy and Breastfeeding: Use of GLEMPA LM ER is generally advised to be avoided during pregnancy due to limited information on its effects. Consult your doctor if pregnant or breastfeeding.
• Drug Interactions: Avoid alcohol consumption as it can increase the risk of low blood sugar (hypoglycemia) or dehydration. Close monitoring of blood sugar is crucial if taking with insulin or sulfonylureas, as this can heighten the risk of hypoglycemia. Diuretics may increase the risk of dehydration and low blood pressure. Inform your doctor about all other medications, supplements, or herbal products you are taking.
• General Warnings: Monitor blood sugar levels regularly. Stay well-hydrated, especially during physical activity or hot weather. Maintain good hygiene to prevent infections. This medication may cause dizziness, so exercise caution when driving or operating machinery.

Storage Store GLEMPA LM ER tablets at room temperature, ideally below 30°C, away from moisture, excessive heat, and direct light. Keep the medicine out of reach of children and pets. Do not use the medication past its expiration date.

Here are frequently asked questions about GLEMPA LM ER 10/5/1000MG TAB, a medication for type 2 diabetes.

What is GLEMPA LM ER 10/5/1000MG TAB used for?

GLEMPA LM ER 10/5/1000MG TAB is a combination medication used to improve blood sugar control in adults with type 2 diabetes mellitus, alongside diet and exercise. It also helps reduce the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease.

How does GLEMPA LM ER 10/5/1000MG TAB work?

This medicine combines three active ingredients:

• Empagliflozin: This acts as an SGLT2 inhibitor, blocking a protein in the kidneys (SGLT-2) to prevent glucose reabsorption, thus causing excess blood sugar to be removed through urine.
• Linagliptin: This works as a DPP-4 inhibitor, increasing the body's natural insulin production when blood sugar levels are high and reducing glucose production by the liver.
• Metformin (Extended Release): This is a biguanide that reduces the absorption of sugar from the stomach, decreases the release of stored sugar from the liver, and helps the body use insulin more effectively.

What is the usual dosage for GLEMPA LM ER 10/5/1000MG TAB?

The typical dosage is one tablet of 10 mg empagliflozin, 5 mg linagliptin, and 1000 mg metformin (extended-release) taken once a day, usually with a meal in the morning. Your doctor will determine the specific dosage based on your current regimen and renal function. It's important to swallow the extended-release tablet whole without crushing, breaking, or chewing it.

What are the possible side effects of GLEMPA LM ER 10/5/1000MG TAB?

Common side effects may include urinary tract infections (UTIs), nasopharyngitis (common cold symptoms), upper respiratory tract infections, diarrhea, and headache. More serious but less common side effects can include lactic acidosis (due to metformin), diabetic ketoacidosis, dehydration, genital yeast infections, and pancreatitis. If you experience severe stomach pain, unusual muscle pain, trouble breathing, or symptoms of an allergic reaction, seek immediate medical attention.

Is GLEMPA LM ER 10/5/1000MG TAB safe during pregnancy or breastfeeding?

GLEMPA LM ER 10/5/1000MG TAB is generally not recommended during pregnancy or while breastfeeding. There is limited information on its safety during pregnancy, and for breastfeeding, it's not known how much passes into breast milk, but it could potentially affect the baby's blood sugar or kidney development. Discuss alternative diabetes treatments with your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can GLEMPA LM ER 10/5/1000MG TAB be taken with other medications?

It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid possible interactions. Concurrent use with insulin or sulfonylureas (like glyburide, glimepiride) can increase the risk of low blood sugar (hypoglycemia). Taking it with diuretics (water pills) can increase the risk of dehydration and low blood pressure. Certain medications like cimetidine, trimethoprim, and iodinated contrast agents can affect metformin levels or increase the risk of lactic acidosis.

What precautions should be taken while using GLEMPA LM ER 10/5/1000MG TAB?

Before starting this medication, inform your doctor if you have kidney or liver problems, a history of urinary tract infections, heart failure, or pancreatitis. Stay well-hydrated, especially during physical activity or in hot weather, as the medication can cause dehydration. Limit or avoid alcohol consumption, as it can increase the risk of lactic acidosis. Your doctor may temporarily discontinue this medication before certain X-ray procedures with contrast agents or before surgery.

What happens if a dose of GLEMPA LM ER 10/5/1000MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should GLEMPA LM ER 10/5/1000MG TAB be stored?

Store GLEMPA LM ER 10/5/1000MG TAB at room temperature, away from moisture, excessive heat, and direct light. Keep it out of reach of children and pets. Do not use the medication past its expiration date.