Repace 100 Tablet (10 Tab)

REPACE 100 TABLET

REPACE 100 TABLET, manufactured by SUN PHARMA LABORATORIES LTD., is a medication primarily used for managing cardiovascular conditions.

• Name

  • Brand Name: Repace 100 Tablet
  • Common Name: Losartan (Losartan Potassium)

• Composition

  • Each tablet contains Losartan 100 mg.

• Uses REPACE 100 TABLET is prescribed for several medical conditions:

  • Hypertension (High Blood Pressure): It helps relax blood vessels, reducing pressure on the heart and improving cardiovascular health.
  • Diabetic Nephropathy: It slows kidney damage in individuals with type 2 diabetes and high blood pressure, reducing proteinuria and delaying disease progression.
  • Chronic Heart Failure: It improves heart function and reduces symptoms such as tiredness, shortness of breath, and swollen legs.
  • Prevention of Heart Attack and Stroke: By lowering blood pressure and improving blood flow, it reduces the risk of serious cardiovascular complications.
  • Reduction of Stroke Risk in Left Ventricular Hypertrophy: It is used to decrease the risk of stroke in people with high blood pressure and an enlarged left ventricle.

• Dosage and Administration

  • REPACE 100 TABLET is typically taken once daily, preferably at the same time each day to maintain consistent blood levels.
  • It can be taken with or without food.
  • Swallow the tablet whole with water; do not crush, chew, or break it.
  • The dosage may vary based on the patient's condition and response to the medication, and should always be as prescribed by a doctor.
  • It is not recommended for children under 6 years of age (some sources state under 8 years).

• Side Effects Most side effects are usually mild and resolve over time, but persistent or severe effects should be reported to a doctor. Common side effects include:

  • Dizziness
  • Tiredness/Weakness
  • Low blood pressure (hypotension)
  • Hyperkalemia (high potassium levels in the blood)
  • Hypoglycemia (low blood sugar)
  • Anemia
  • Changes in kidney function (e.g., decreased urine output, edema)
  • Abdominal pain, constipation, diarrhea
  • Sore throat, cough
  • Serious side effects include signs of severe allergic reactions like rash, itching, swelling of the face, lips, mouth, or throat, and difficulty breathing.

• Precautions

  • Pregnancy: REPACE 100 TABLET is unsafe and not recommended during pregnancy, especially in the second and third trimesters, as it can cause serious harm or death to the unborn baby.
  • Breastfeeding: Avoid breastfeeding while taking this medicine as it may be unsafe for the baby.
  • Allergy: Do not take if allergic to Losartan or any of its components.
  • Liver and Kidney Impairment: Use with caution in patients with liver or kidney disease. It is not recommended for those with severely impaired liver or kidney function. Regular monitoring of kidney function is advised.
  • Alcohol: Avoid alcohol consumption as it may increase the risk of low blood pressure and adverse effects.
  • Potassium Supplements/Rich Foods: Avoid potassium supplements and foods rich in potassium (e.g., bananas) due to the risk of hyperkalemia.
  • Drug Interactions: Inform your doctor about all medications, supplements, or herbal preparations, especially:
    • NSAIDs (e.g., ibuprofen): May reduce the blood pressure-lowering effect and increase kidney risk.
    • Aliskiren: Not recommended, especially in diabetic patients or those with kidney problems, due to increased risk of side effects.
    • Lithium: May increase lithium levels, leading to toxicity.
    • Diuretics ("water pills"), other antihypertensives, certain antibiotics (e.g., trimethoprim), and corticosteroids.
  • Driving and Machinery: REPACE 100 TABLET may cause dizziness or drowsiness; exercise caution when driving or operating machinery.
  • Other Conditions: Use with caution in patients with heart failure, heart valve problems, irregular heartbeat, or coronary heart disease.

• Storage

  • Store in a cool and dry place.
  • Protect from sunlight and moisture.
  • Store at temperatures between 10ºC to 25ºC or below 30ºC.
  • Keep out of sight and reach of children.

REPACE 100 TABLET is a medication primarily used to treat high blood pressure (hypertension). It contains Losartan, an angiotensin II receptor blocker (ARB), as its active ingredient.

Here are some frequently asked questions about REPACE 100 TABLET:

What is REPACE 100 TABLET used for?

REPACE 100 TABLET is primarily used to treat high blood pressure (hypertension). It is also prescribed to reduce the risk of heart attack and stroke, manage diabetic nephropathy (kidney disease associated with type 2 diabetes and high blood pressure), and to decrease the risk of stroke in individuals with high blood pressure and left ventricular hypertrophy (enlargement of the heart's left side).

How does REPACE 100 TABLET work?

REPACE 100 TABLET contains Losartan, which is an angiotensin II receptor blocker (ARB). It works by blocking the action of angiotensin II, a natural substance in the body that causes blood vessels to narrow. By preventing this action, the medication allows blood vessels to relax and widen, leading to lower blood pressure and improved blood flow, which reduces the strain on the heart.

What is the usual dosage?

REPACE 100 TABLET is typically taken once daily, with or without food, at the same time each day to maintain consistent blood levels. The exact dosage and duration will be determined by your doctor based on your age, the severity of your condition, medical history, and how you respond to the initial dose. It should be swallowed whole with water and not crushed, chewed, or broken.

What are the possible side effects?

Common side effects of REPACE 100 TABLET can include dizziness, tiredness, weakness, low blood pressure, and headache. Other possible side effects are low blood sugar (hypoglycemia), high potassium levels in the blood (hyperkalemia), and changes in kidney function. Most side effects are usually mild and resolve on their own, but if they persist or worsen, you should consult your doctor.

Is it safe during pregnancy or breastfeeding?

REPACE 100 TABLET is generally considered unsafe during pregnancy, especially during the second and third trimesters, as it can cause serious harm or even death to the unborn baby. It is also not recommended during breastfeeding, as it may be unsafe for the baby. Pregnant or breastfeeding women should consult their doctor before taking this medication.

Can it be taken with other medications?

REPACE 100 TABLET can interact with various medications. It's important to inform your doctor about all medicines, supplements, or herbal preparations you are taking. Specific interactions include potassium-sparing diuretics, potassium supplements (which can increase the risk of high potassium levels), NSAIDs (like ibuprofen), lithium, certain blood thinners (e.g., warfarin), and other anti-hypertensives. If you have diabetes, you should not take aliskiren with REPACE 100 TABLET.

What precautions should be taken?

Before taking REPACE 100 TABLET, inform your doctor if you have diabetes, kidney or liver problems, heart conditions (like congestive heart failure or left ventricular hypertrophy), a history of angioedema, or are dehydrated. Avoid alcohol consumption as it can increase the risk of low blood pressure and dizziness. Also, avoid potassium supplements and potassium-rich foods. This medicine may cause dizziness or drowsiness, so exercise caution when driving or operating machinery. Regular monitoring of blood pressure, kidney function, and potassium levels may be recommended.

What happens if a dose is missed?

If you miss a dose of REPACE 100 TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should it be stored?

REPACE 100 TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children. Store at temperatures between 10ºC to 25ºC or below 30ºC.