Refzil O Susp 125mg

Refzil O Suspension 125mg

Refzil O Suspension 125mg is an antibiotic medication primarily used to combat various bacterial infections. It is manufactured by Sun Pharmaceutical Industries Ltd.

• Name:

  • Common Name: Refzil O Suspension, Refzil O Oral Suspension
  • Brand Name: REFZIL O (by SUN RANBAXY-STANLIFE DIV, part of Sun Pharmaceutical Industries Ltd.)

• Composition:

  • Active Ingredient: Cefprozil (125 mg per 5 ml).
  • Refzil O Suspension belongs to the cephalosporin class of antibiotics.

• Uses: Refzil O Suspension is prescribed for the management of various bacterial infections in children. It is effective against a broad spectrum of bacteria and is used for:

  • Respiratory tract infections, including pneumonia and bronchitis.
  • Urinary tract infections.
  • Ear infections (otitis media), sinus infections (sinusitis), and throat infections (pharyngitis, tonsillitis).
  • Skin and soft tissue infections. It is crucial to note that Refzil O Suspension is not effective against viral infections like the common cold or flu.

• Dosage and Administration:

  • Administer Refzil O Suspension orally, with or without food.
  • Shake the bottle well before each use.
  • For powder for oral suspension, reconstitute with sterile water as per the instructions on the label.
  • Measure the prescribed quantity using the provided device (measuring cup, spoon, or dropper) to ensure accurate dosing. Avoid using household spoons.
  • The dosage and duration of treatment are determined by the doctor based on the child's age, body weight, and the severity of the infection.
  • Complete the full course of medication as prescribed, even if symptoms improve, to prevent the infection from returning and to reduce the risk of antibiotic resistance.
  • Refzil O Suspension is generally not recommended for infants below 6 months of age due to a lack of safety data.

• Side Effects:

  • Common: Nausea, diarrhea, vomiting, dizziness, abdominal pain, genital itching, vaginal inflammation, increased liver enzymes, and increased white blood cell count (eosinophils).
  • Serious: Allergic reactions (rash, itching, swelling of face/mouth, difficulty breathing), severe blistering or peeling of skin, bloody diarrhea, fever, chills, and flu-like symptoms. Inform your doctor immediately if any serious side effects occur or common side effects persist or worsen. Prolonged use may lead to superinfection or Clostridium difficile-associated diarrhea (CDAD).

• Precautions:

  • Do not administer if allergic to Cefprozil, penicillins, or other cephalosporin antibiotics.
  • Use with caution in children with kidney problems, and dose adjustments may be necessary.
  • Caution is advised in patients with liver issues or a history of gastrointestinal diseases like colitis.
  • Consult a doctor if pregnant or breastfeeding.
  • Avoid self-medication to prevent antibiotic resistance.
  • Antacids containing aluminum or magnesium may decrease absorption; administer at least 2 hours before or after Refzil O Suspension.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • The ideal storage temperature should not exceed 30°C.
  • Keep the bottle tightly closed to prevent exposure to air.
  • Always keep the medicine out of reach of children.
  • Reconstituted suspensions should typically be stored in a refrigerator.

Here are some frequently asked questions about REFZIL O SUSP 125MG (Cefprozil Oral Suspension):

What is Refzil O Suspension used for?

Refzil O Suspension is an antibiotic medication primarily used to treat various bacterial infections in children. These include infections of the lungs (like pneumonia), urinary tract, ears (otitis media), nasal sinuses (sinusitis), and throat (pharyngitis/tonsillitis), as well as skin and skin-structure infections.

How does Refzil O Suspension work?

Refzil O Suspension contains Cefprozil, which is a cephalosporin antibiotic. It works by interfering with the bacteria's ability to form their cell walls. The cell wall is a crucial protective layer for bacteria; by inhibiting its synthesis, Cefprozil weakens the bacterial cell, leading to cell lysis and death.

What is the usual dosage of Refzil O Suspension?

The dosage of Refzil O Suspension is determined by a doctor based on the child's age, body weight, the severity of the infection, and specific condition being treated. It is generally taken orally, usually once or twice daily, for a course duration of about 10 days, or as prescribed. It is crucial to follow the doctor's instructions strictly regarding the dose and duration.

What are the possible side effects of Refzil O Suspension?

Common side effects may include nausea, diarrhea, vomiting, dizziness, abdominal pain, headache, and sometimes genital itching or vaginal inflammation. Some individuals might also experience an increase in liver enzymes or white blood cell count (eosinophils). Most side effects are temporary and usually resolve on their own. However, if any serious or persistent side effects occur, such as severe diarrhea, allergic reactions (rash, swelling, difficulty breathing), or liver-related issues, medical attention should be sought immediately.

Is Refzil O Suspension safe during pregnancy or breastfeeding?

While animal studies have shown low or no adverse effects, limited human studies are available for pregnancy. Refzil O Suspension is generally considered safe for use during pregnancy and breastfeeding when prescribed and monitored by a doctor, who will weigh the potential risks and benefits. Close monitoring of the infant for any undesired side effects is recommended during breastfeeding.

Can Refzil O Suspension be taken with other medications?

Yes, but caution is advised. Refzil O Suspension can interact with certain medications. For example, Probenecid may increase the blood levels of Cefprozil, and mixing it with aminoglycoside antibiotics (like gentamicin, tobramycin) can heighten the risk of kidney damage. It is important to inform your doctor about all other medications your child is currently taking to avoid potential interactions.

What precautions should be taken?

Inform your doctor if your child has a history of allergies to antibiotics, especially penicillin or other cephalosporins, or if they have kidney or gastrointestinal diseases like colitis. Refzil O Suspension should be used with caution in children with kidney disease, as dose adjustments may be necessary. It is important to complete the entire course of medication as prescribed, even if symptoms improve, to prevent the infection from recurring and to avoid antibiotic resistance.

What happens if a dose is missed?

If a dose of Refzil O Suspension is missed, it should be given as soon as remembered. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to compensate for a missed one.

How should it be stored?

Refzil O Suspension should be stored in a cool, dry place, away from direct sunlight and out of the reach of children. After reconstitution, it may need to be refrigerated, depending on specific product instructions.

Is Refzil O Suspension effective against the common cold or flu?

No, Refzil O Suspension is an antibiotic and is only effective against bacterial infections. It will not work for viral infections such as the common cold or flu. Using antibiotics when they are not needed can lead to antibiotic resistance, making them less effective for future bacterial infections.