Dolokind Sr Tab

DOLOKIND SR TAB by MANKIND PHARMA LTD

Name:

• Brand Name: Dolokind SR Tablet
• Common Name: Aceclofenac Sustained Release Tablet

Composition: Each tablet contains Aceclofenac 200 mg. Dolokind SR is a Non-Steroidal Anti-Inflammatory Drug (NSAID) that works by blocking the production of certain chemical messengers (prostaglandins) in the body that cause pain and inflammation.

Uses: Dolokind SR Tablet is prescribed for the relief of pain, inflammation, and swelling associated with various conditions. These include:

• Osteoarthritis
• Rheumatoid Arthritis
• Ankylosing Spondylitis
• Headaches, toothaches, backaches, and menstrual pain
• Sprains, strains, and other musculoskeletal disorders
• Post-operative pain and inflammation
• Fever reduction

Dosage and Administration: Dolokind SR Tablet should be taken orally as a whole with a glass of water, as prescribed by your doctor. Do not chew, crush, or break the tablet. It is recommended to take the tablet with food or milk to minimize stomach irritation. Take it consistently at the same time each day for optimal results. Do not exceed the prescribed dose or discontinue the medicine without consulting your doctor.

Side Effects: Common side effects may include:

• Dizziness, drowsiness, visual disturbances
• Nausea, vomiting, stomach pain, indigestion, diarrhea, heartburn
• Skin rash
• Increased liver enzymes Serious side effects, though rare, can include gastrointestinal bleeding, ulcers, heart attack, stroke, or severe allergic reactions.

Precautions:

• Avoid if allergic to Aceclofenac or other NSAIDs.
• Not recommended during pregnancy (especially the third trimester) or breastfeeding.
• Use with caution in patients with a history of heart disease, high blood pressure, liver or kidney problems, asthma, gastrointestinal disorders (like ulcers or bleeding), or blood clotting disorders.
• Alcohol consumption should be avoided as it may increase drowsiness and the risk of stomach problems or bleeding.
• Not recommended for children under 18 years of age.
• Caution is advised while driving or operating machinery if experiencing dizziness or visual disturbances.
• Inform your doctor about all other medications you are taking, as interactions can occur. Long-term use may require monitoring of kidney function, liver function, and blood components.

Storage: Store below 25°C or 30°C. Keep away from direct sunlight, moisture, and out of the reach of children.

What is DOLOKIND SR TAB used for?

DOLOKIND SR TAB is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for pain relief and to reduce inflammation and swelling. It is prescribed for conditions affecting joints and muscles, such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It can also alleviate various types of pain including low back pain, dental pain, gynecological pain, headaches, toothaches, muscle pain, menstrual cramps, sprains, and strains, as well as assist in post-operative recovery.

How does DOLOKIND SR TAB work?

DOLOKIND SR TAB works by blocking the release of certain chemical messengers in the brain called prostaglandins. These prostaglandins are responsible for causing pain, swelling, and inflammation in the body. By inhibiting the cyclo-oxygenase (COX) enzyme, which is involved in prostaglandin production, DOLOKIND SR TAB effectively reduces these symptoms.

What is the usual dosage of DOLOKIND SR TAB?

The dosage of DOLOKIND SR TAB should be strictly as advised by your doctor. It is typically taken once or twice daily. The tablet should be swallowed whole with a glass of water, without crushing, chewing, or breaking it. It is recommended to take DOLOKIND SR TAB with food or milk to help prevent an upset stomach and improve absorption. Consistent intake at the same time each day can enhance its effectiveness.

What are the possible side effects of DOLOKIND SR TAB?

Common side effects of DOLOKIND SR TAB include vomiting, stomach pain (epigastric pain), nausea, indigestion, diarrhea, heartburn, and loss of appetite. It may also cause dizziness, drowsiness, or visual disturbances. More serious complications can occur with long-term use, such as stomach bleeding, kidney problems, heart attack, or stroke. If you experience persistent or severe side effects, or any signs of stomach bleeding (e.g., blood in stools, coffee-colored vomit), consult your doctor immediately.

Is DOLOKIND SR TAB safe during pregnancy or breastfeeding?

DOLOKIND SR TAB is generally not recommended during pregnancy, especially in the third trimester, as it may cause harmful effects on the unborn child and the mother, including reducing labor. Similarly, it is not recommended during breastfeeding due to limited information on its safety and whether it passes into breast milk. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medicine.

Can DOLOKIND SR TAB be taken with other medications?

DOLOKIND SR TAB can interact with several medications. It may reduce the blood pressure-lowering effect of anti-hypertensive medicines (e.g., enalapril, losartan). Taking it with steroids can increase the risk of stomach ulcers and bleeding. It may also enhance the anticoagulant effects of warfarin, requiring close monitoring. Caution is advised when used with diuretics, ciclosporin, tacrolimus, digoxin, methotrexate, mifepristone (avoid for 8-12 days after mifepristone), certain anti-HIV medicines, anti-diabetic medicines, lithium, and zidovudine. Combining it with other NSAIDs can increase the risk of stomach ulcers, bleeding, and kidney problems, and should only be done under medical approval. Always inform your doctor about all medicines, supplements, or herbal products you are taking.

What precautions should be taken while using DOLOKIND SR TAB?

Take DOLOKIND SR TAB with food or milk to reduce stomach irritation. Avoid consuming alcohol as it can increase drowsiness and the risk of stomach problems and bleeding. Due to potential dizziness, drowsiness, or visual disturbances, exercise caution while driving or performing tasks that require concentration. Inform your doctor if you have a history of heart disease, stroke, kidney or liver problems, asthma, diabetes, high blood pressure, blood clots, stomach ulcers, or bleeding disorders. Long-term use may necessitate regular monitoring of kidney function, liver function, and blood component levels. It is not recommended for children. Avoid if you are allergic to aceclofenac or other NSAIDs like ibuprofen or diclofenac.

What happens if a dose of DOLOKIND SR TAB is missed?

If you forget to take a dose of DOLOKIND SR TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one, as this can increase the risk of side effects.

How should DOLOKIND SR TAB be stored?

DOLOKIND SR TAB should be stored below 30°C (or 25°C). Keep it in a cool, dry place, away from direct sunlight and moisture. Ensure it is kept out of the reach of children and pets.