Advent (tangy Orange Flavour) 228.5 Mg Dispersable Tablet (10 Tablet)

ADVENT (Tangy Orange Flavour) 228.5 MG Dispersable Tablet is an antibiotic medication manufactured by Cipla Ltd., formulated to combat a variety of bacterial infections. Its dispersible form, with a tangy orange flavor, facilitates easier administration, especially for children and those with difficulty swallowing.

Name

• Brand Name: Advent DT 228.5mg Tablet
• Common Name: Amoxicillin and Clavulanic Acid Dispersable Tablet
• Manufacturer: Cipla Ltd.

Composition

• Active Ingredients: Each tablet contains Amoxicillin (200 mg) and Clavulanic acid (28.5 mg).

Uses

ADVENT is prescribed for managing a broad spectrum of bacterial infections, including:

• Middle ear and sinus infections
• Respiratory tract infections (lungs, airways)
• Genital and urinary tract infections
• Skin and soft tissue infections, such as dental infections
• Bone and joint infections
• Septic abortion and abdominal infections
• It is also effective against resistant tuberculosis (in its broader application of active ingredients).

Dosage and Administration

• Take ADVENT as directed by a healthcare professional.
• The tablet should be dissolved in water before consumption.
• It is advisable to take this medicine after meals to minimize stomach discomfort.
• Complete the full course of treatment as prescribed, even if symptoms improve, to prevent antibiotic resistance.

Side Effects

Common side effects may include:

• Nausea, vomiting
• Diarrhea, indigestion, stomach pain Serious, though rare, side effects or overdose symptoms can include skin rash, drowsiness, hyperactivity, decreased urination, and allergic reactions (e.g., severe rash, itching, swelling, difficulty breathing). Contact your doctor immediately if any severe or persistent side effects occur.

Precautions

• Do not take if you have a known allergy to penicillin or any components of ADVENT, or a history of liver problems/jaundice from previous antibiotic use.
• Inform your doctor if you have kidney or liver disease, glandular fever, or difficulty passing urine. Dose adjustments may be necessary for patients with kidney or liver impairment.
• Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.
• Avoid foods high in iron or excessive calcium, as these might affect the medicine's efficacy.

Storage

• Store in a cool, dry place away from direct sunlight and moisture.
• Keep out of the sight and reach of children.
• Recommended storage temperature is between 10ºC to 25ºC or below 30ºC.

ADVENT (Tangy Orange Flavour) 228.5 mg Dispersable Tablet, manufactured by Cipla Ltd., is an antibiotic medicine commonly known as Co-amoxiclav. It contains a combination of two active ingredients: Amoxicillin and Clavulanic Acid.

What is ADVENT (Co-amoxiclav) used for?

ADVENT is a broad-spectrum antibiotic used to treat a variety of bacterial infections. These include infections of the ear, nose, throat (e.g., otitis media, sinusitis, tonsillitis), respiratory tract (e.g., bronchitis, pneumonia), urinary tract, skin and soft tissue (e.g., cellulitis, abscesses), bone and joint, and dental infections. It is also effective against certain bacteria that have developed resistance to other antibiotics and can be used to treat drug-resistant tuberculosis.

How does ADVENT (Co-amoxiclav) work?

ADVENT works through the combined action of its two components. Amoxicillin is a penicillin-class antibiotic that kills bacteria by preventing the formation of their cell walls, which are essential for their survival. However, some bacteria produce an enzyme called beta-lactamase that can break down amoxicillin, making it ineffective. Clavulanic acid is a beta-lactamase inhibitor that inactivates this enzyme, thereby protecting amoxicillin and allowing it to work optimally against a wider range of bacteria, including those that are typically resistant.

What is the usual dosage of ADVENT 228.5 mg Dispersable Tablet?

The dosage of ADVENT 228.5 mg Dispersable Tablet depends on the type and severity of the infection, and the patient's age and weight. For children, the dose is typically worked out based on their weight by a doctor. It is often given three times a day, with doses spaced evenly, at least 4 hours apart. Children aged 6 years and below, or those weighing less than 40 kg, are often prescribed suspensions or dispersible tablets. The tablets are generally not suitable for children weighing less than 25 kg. Always follow your doctor's instructions for the specific dosage and duration of treatment.

How should ADVENT (Co-amoxiclav) be taken?

ADVENT Dispersable Tablets should be taken as directed by your doctor. They can be dissolved in water before consumption. It is advisable to take this medicine with a meal or snack to help reduce stomach discomfort. It is crucial to complete the full course of antibiotics as prescribed by your doctor, even if you start to feel better, to prevent the infection from returning and to reduce the risk of antibiotic resistance.

What are the possible side effects of ADVENT (Co-amoxiclav)?

Common side effects of ADVENT (Co-amoxiclav) can include diarrhea, nausea, vomiting, and thrush (oral or vaginal yeast infection). These often improve as your body adjusts to the medicine. More serious, but rare, side effects can include severe allergic reactions (e.g., swollen face or mouth, difficulty breathing, widespread itchy rash), severe watery or bloody diarrhea, stomach pain with fever (signs of large intestine inflammation), or signs of liver problems (e.g., yellowing of skin/eyes, pale stool, dark urine). If you experience any severe symptoms, seek immediate medical attention.

Is ADVENT (Co-amoxiclav) safe during pregnancy or breastfeeding?

ADVENT (Co-amoxiclav) can be taken during pregnancy, but it is recommended to consult your doctor to ensure it is suitable for your specific situation. Amoxicillin, one of the active ingredients, is generally considered safe during pregnancy, although some studies have suggested a very rare, small increased risk of cleft palate if used in the first trimester, while many other studies show no harmful effects.

Co-amoxiclav passes into breast milk in small amounts and is generally considered safe while breastfeeding. However, it is important to monitor the baby for any mild side effects such as diarrhea, thrush, or rash. If you have any concerns, talk to your doctor or pharmacist.

Can ADVENT (Co-amoxiclav) be taken with other medications?

It is important to inform your doctor about all other medications, including over-the-counter drugs, herbal remedies, and supplements, you are taking. ADVENT (Co-amoxiclav) can interact with certain medicines, such as:

• Allopurinol or probenecid (used for gout): May increase the likelihood of allergic skin reactions or increase amoxicillin levels.
• Warfarin or other anticoagulants: May increase the risk of bleeding, requiring closer monitoring of blood tests.
• Methotrexate (used for cancer or rheumatic diseases): May increase methotrexate toxicity.
• Mycophenolate mofetil (used to prevent organ rejection): May reduce its effectiveness.
• Oral contraceptives: The effectiveness of oral contraceptives may be reduced if you experience severe vomiting or diarrhea for more than 24 hours while taking the antibiotic. Additional contraceptive precautions may be needed in such cases.
• Oral typhoid vaccine: Co-amoxiclav may stop the oral typhoid vaccine from working.

What precautions should be taken?

Before taking ADVENT (Co-amoxiclav), tell your doctor if you:

• Have a known allergy to penicillin, cephalosporins, or any other antibiotics.
• Have a history of liver problems or jaundice (yellowing of the skin or eyes), especially after taking antibiotics.
• Have kidney problems, as your dose may need adjustment.
• Have glandular fever (infectious mononucleosis), as it can cause a rash.
• Are not passing water regularly.
• Are having blood or urine tests, as this medicine can affect the results.

It's also important to drink plenty of water while taking this medicine.

What happens if a dose is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a forgotten dose.

How should it be stored?

ADVENT (Tangy Orange Flavour) 228.5 mg Dispersable Tablets should be stored in a cool, dry place, away from direct heat and light, and out of the reach of children. Once the pouch is opened, the tablets should be used within 30 days. If the medicine is provided as a liquid suspension (which might be prepared from a dry syrup/powder form like Advent), it usually needs to be kept in a refrigerator and should not be used for longer than 7 to 14 days after being made up by the pharmacy. Always check the specific storage instructions on the medicine packaging.