Aceclo Plus

ACECLO PLUS

ACECLO PLUS is a widely used medication manufactured by Aristo Pharmaceuticals Pvt Ltd, designed to provide comprehensive relief from pain, inflammation, and fever. It is a combination drug often prescribed for various musculoskeletal and inflammatory conditions.

• Name:

  • Brand Name: ACECLO PLUS
  • Common Name: Aceclofenac and Paracetamol Tablets

• Composition:

  • Each tablet typically contains:
    • Aceclofenac: 100 mg
    • Paracetamol (Acetaminophen): 325 mg

• Uses: ACECLO PLUS is prescribed for the short-term relief of pain, inflammation, and swelling in various conditions affecting joints and muscles. These include:

  • Rheumatoid Arthritis
  • Osteoarthritis
  • Ankylosing Spondylitis
  • Muscle pain, including back pain
  • Headache and mild migraine
  • Dental pain and toothache
  • Pain in the ear and throat
  • Post-operative pain
  • Dysmenorrhea (painful menstruation)
  • General pain and inflammation, and fever reduction

• Dosage and Administration:

  • The dosage should be strictly followed as prescribed by a doctor, based on the patient's age, medical condition, and symptom severity.
  • Adults: Typically, 1 tablet twice a day (morning and evening) is recommended.
  • It is generally advised to take the medicine after meals to minimize the risk of stomach upset.
  • Do not exceed the recommended dose or duration without consulting a doctor.

• Side Effects: Common side effects may include:

  • Nausea
  • Vomiting
  • Stomach pain / epigastric pain
  • Heartburn
  • Diarrhea
  • Dizziness
  • Headache
  • Rash or itching
  • Oedema (swelling, typically in feet, ankles, or hands) Serious side effects, though less common, can include stomach ulcers or bleeding, liver damage, kidney problems, and allergic reactions (like swelling of the face, lips, or tongue, and difficulty breathing).

• Precautions:

  • Inform your doctor about any pre-existing medical conditions, especially heart, kidney, or liver problems, stomach ulcers, high blood pressure, or asthma.
  • Avoid taking ACECLO PLUS if you have a known allergy to aceclofenac, paracetamol, or other NSAIDs.
  • Pregnancy and Breastfeeding: Not recommended during the third trimester of pregnancy and generally advised against during breastfeeding unless deemed essential by a doctor.
  • Alcohol: Avoid consuming alcohol as it can increase the risk of liver damage and stomach irritation.
  • Driving and Operating Machinery: ACECLO PLUS may cause dizziness and drowsiness, so avoid these activities until you know how the medicine affects you.
  • Drug Interactions: Inform your doctor about all other medications you are taking. Interactions can occur with anticoagulants (e.g., warfarin), corticosteroids (e.g., prednisone), Selective Serotonin Reuptake Inhibitors (SSRIs), and certain antidiabetic medicines.
  • Long-term use can potentially damage kidneys and liver.

• Storage:

  • Store in a cool and dry place, away from direct heat and sunlight.
  • Keep the medicine below 30°C.
  • Keep out of sight and reach of children and pets.

ACECLO PLUS is a medication manufactured by Aristo Pharmaceuticals Pvt Ltd, commonly used for its pain-relieving and anti-inflammatory properties. It is a fixed-dose combination of Aceclofenac and Paracetamol (also known as Acetaminophen).

What is ACECLO PLUS used for?

ACECLO PLUS is primarily used to manage pain and inflammation associated with various conditions. These include osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also effective for musculoskeletal disorders, back pain, joint pain, muscle pain, sprains, strains, toothaches, headaches, throat pain, and ear pain. Additionally, it helps reduce fever and provides relief from post-operative pain and gynecological pain, such as uterine cramps and painful menstruation.

How does ACECLO PLUS work?

ACECLO PLUS contains two active ingredients: Aceclofenac and Paracetamol. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting cyclooxygenase (COX) enzymes, which are responsible for producing prostaglandins—chemicals that cause pain, inflammation, and fever. Aceclofenac also supports cartilage matrix synthesis, aiding in cartilage repair. Paracetamol acts as an analgesic (pain reliever) and antipyretic (fever reducer) by inhibiting prostaglandin synthesis primarily in the central nervous system, thereby reducing pain perception and fever. Together, these ingredients provide comprehensive relief from pain and inflammation.

What is the usual dosage for ACECLO PLUS?

For adults, the typical recommended dosage is one tablet in the morning and one tablet in the evening, with a maximum of two tablets per day. It is generally advised to take ACECLO PLUS with food or milk to help prevent gastric irritation. It's important to maintain a gap of 4-6 hours between doses and not to exceed the prescribed daily dosage.

What are the possible side effects of ACECLO PLUS?

Common side effects can include nausea, vomiting, abdominal pain, diarrhea, constipation, heartburn, indigestion, dizziness, fatigue, drowsiness, and headache. Less common or more serious side effects may include gastric ulcers, mouth ulcers, allergic skin reactions or rashes, cloudy urine with blood, and increased liver enzymes. Serious risks, especially with overdose or concomitant alcohol use, involve liver damage, gastrointestinal bleeding, and kidney damage (nephrotoxicity).

Is ACECLO PLUS safe during pregnancy or breastfeeding?

ACECLO PLUS is generally not recommended during pregnancy, especially in the third trimester, as it may pose potential risks such as heart defects in the fetus or delayed birth. Pregnant women should consult their healthcare provider for alternative pain relief options. For breastfeeding mothers, the use of ACECLO PLUS is also not recommended, as small amounts of the medication's components may pass into breast milk. It is crucial to consult a healthcare provider before taking this medicine while breastfeeding to assess potential risks and benefits.

Can ACECLO PLUS be taken with other medications?

Caution is advised when taking ACECLO PLUS with other medications. It should not be taken with other NSAIDs or corticosteroids due to an increased risk of side effects. Interactions can occur with blood thinners (anticoagulants like warfarin), diuretics, lithium, digoxin, methotrexate, and quinolone antibiotics. It is important to avoid taking ACECLO PLUS with any other medicine containing paracetamol to prevent accidental overdose. The risk of liver damage can also be increased if taken with certain drugs (e.g., barbiturates, carbamazepine, isoniazid, rifampin) or if there is chronic alcohol consumption.

What precautions should be taken while using ACECLO PLUS?

Do not take ACECLO PLUS if you are allergic to aceclofenac, paracetamol, aspirin, or other NSAIDs. Exercise caution if you have pre-existing conditions such as heart disease (e.g., heart failure, high blood pressure), liver or kidney problems, asthma, or gastrointestinal diseases (e.g., peptic ulcers, Crohn's disease, ulcerative colitis, history of GI bleeding). Alcohol consumption should be avoided as it can increase the risk of liver damage and stomach bleeding. Since this medicine may cause dizziness or drowsiness, it is advisable to avoid driving or operating heavy machinery until you know how it affects you. For long-term treatment, regular monitoring of renal function, liver function, and blood counts is recommended.

What happens if a dose of ACECLO PLUS is missed?

If you miss a dose of ACECLO PLUS, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should ACECLO PLUS be stored?

ACECLO PLUS should be stored in a cool, dry place, protected from heat, light, and moisture. It is generally recommended to store it at room temperature, typically below 25°C or 30°C. Always keep the medicine out of the reach of children.