Empaglyde M 500mg Tab

Empaglyde M 500mg Tablet

Name

Brand Name: Empaglyde M 500mg Tablet Manufacturer: Mankind Pharma Ltd.

Composition

Each tablet contains:

• Empagliflozin: 12.5 mg
• Metformin Hydrochloride: 500 mg

Uses

Empaglyde M 500mg Tablet is primarily used to manage Type 2 Diabetes Mellitus in adults. It is prescribed as an adjunct to diet and exercise to improve blood sugar control. This medicine works by removing excess glucose from the body through urine and by increasing the body's sensitivity to insulin. Additionally, it may help reduce the risk of cardiovascular death, hospitalization for heart failure, and progression of chronic kidney disease in adult patients with established cardiovascular disease or heart failure.

Dosage and Administration

This medication should be taken orally, typically once daily in the morning, with or without food, as directed by a healthcare professional. The dosage is individualized based on the patient's medical condition and response to treatment. Tablets should be swallowed whole and not chewed, crushed, or broken. It is crucial not to discontinue the medicine without consulting a doctor.

Side Effects

Common side effects may include:

• Frequent urination
• Mild skin rash or itchy skin
• Nausea, vomiting, diarrhea, stomach ache, loss of appetite
• Urinary tract infections
• Genital fungal infections
• Nasopharyngitis
• Hypoglycemia (low blood sugar), especially when used with other antidiabetic medicines, alcohol, or if meals are delayed/missed.
• Joint pain Serious, but rare, side effects such as lactic acidosis may occur due to the metformin component.

Precautions

• Contraindications: Empaglyde M 500mg Tablet is not recommended for individuals with Type 1 diabetes mellitus, severe kidney or liver disease, metabolic acidosis, or diabetic pre-coma. It is also not recommended for individuals under 18 or over 85 years of age.
• Pregnancy and Breastfeeding: Consult a doctor before use, as it may be unsafe during pregnancy and is generally not recommended during breastfeeding.
• Alcohol: Avoid excessive alcohol intake, as it can increase the risk of lactic acidosis and low blood sugar levels.
• Other Conditions: Use with caution in patients with dehydration, severe infection, or those taking diuretics. Inform your doctor about all existing medical conditions and current medications.
• Driving: Fluctuations in blood sugar may cause dizziness or drowsiness, potentially affecting the ability to drive or operate machinery.

Storage

Store Empaglyde M 500mg Tablet in a cool and dry place, away from direct sunlight, and out of reach of children and pets. The recommended storage temperature is below 30°C.

Here are some frequently asked questions about EMPAGLYDE M 500MG TAB:

What is EMPAGLYDE M 500MG TAB used for?

EMPAGLYDE M 500MG TAB is primarily used to treat type 2 diabetes mellitus in adults, alongside diet and exercise. It helps to control high blood sugar levels. Additionally, it can reduce the risk of cardiovascular death, hospitalization for heart failure, and the worsening of kidney disease in patients with type 2 diabetes and existing heart or kidney conditions.

How does EMPAGLYDE M 500MG TAB work?

This medicine contains two active ingredients: Empagliflozin and Metformin. Empagliflozin works by inhibiting the sodium-glucose co-transporter-2 (SGLT2) in the kidneys, which leads to increased excretion of excess glucose from the body through urine. Metformin reduces glucose production in the liver, decreases the absorption of glucose from the intestines, and improves the body's sensitivity to insulin, helping it use glucose more effectively.

What is the usual dosage for EMPAGLYDE M 500MG TAB?

The dosage is determined by your doctor based on your medical condition and response to treatment. For oral tablets, adults and children 10 years and older typically start with one tablet two times a day with food. The dose should not usually exceed 25 mg of empagliflozin and 2000 mg of metformin per day. It is generally recommended to take it at the same time each day, preferably with meals to minimize stomach upset.

What are the possible side effects of EMPAGLYDE M 500MG TAB?

Common side effects can include frequent urination, mild skin rash or itchy skin, nausea, vomiting, diarrhea, stomach ache, loss of appetite, urinary tract infections (UTIs), and genital fungal infections. More serious but less common side effects can include lactic acidosis (especially with kidney problems, dehydration, or alcohol intake) and hypoglycemia (low blood sugar), particularly when used with other diabetes medications like insulin or sulfonylureas.

Is EMPAGLYDE M 500MG TAB safe during pregnancy or breastfeeding?

EMPAGLYDE M 500MG TAB is generally not recommended during pregnancy, especially in the second and third trimesters, as it could harm an unborn baby. It may also be unsafe during breastfeeding as it might pass into breast milk. It is crucial to consult your doctor if you are pregnant, planning to conceive, or breastfeeding to discuss the risks and benefits.

Can EMPAGLYDE M 500MG TAB be taken with other medications?

This medicine can interact with other medications. It may affect the levels of lithium in the blood and can increase the risk of volume depletion when taken with diuretics (water pills). When taken with insulin or insulin secretagogues, it may increase the risk of low blood sugar. Inform your doctor about all medications, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using EMPAGLYDE M 500MG TAB?

You should not take this medicine if you have type 1 diabetes mellitus, severe kidney or liver disease, or metabolic acidosis. Avoid excessive alcohol intake as it can increase the risk of lactic acidosis and low blood sugar. Stay well-hydrated, especially during exercise or in hot weather, as the medicine can cause fluid loss. Monitor your blood sugar levels regularly and inform your doctor about any pre-existing medical conditions.

What happens if a dose of EMPAGLYDE M 500MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.

How should EMPAGLYDE M 500MG TAB be stored?

EMPAGLYDE M 500MG TAB should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it at a temperature below 30°C. Do not keep outdated medicine or medicine no longer needed, and keep it out of the reach of children.