Ciladoc 50 Tab

CILADOC 50 TAB by LUPIN LTD-PRIMUS

CILADOC 50 TAB is a medication prescribed to alleviate symptoms associated with insufficient blood flow, particularly in the legs.

• Name: CILADOC 50 TAB (Brand name), Cilostazol (Common name)

• Composition: Each tablet contains 50 mg of Cilostazol.

• Uses: CILADOC 50 TAB is primarily used to treat intermittent claudication, a condition characterized by cramp-like pain, ache, discomfort, or fatigue in the legs (typically calves, thighs, buttocks, hips, or feet) that occurs during walking or exercise and improves with rest. It works by widening blood vessels and reducing blood clotting time, thereby increasing blood supply to the limbs and improving the distance a patient can walk without pain.

• Dosage and Administration: The typical adult dosage is 100 mg (two CILADOC 50 TAB tablets) twice daily. It should be taken on an empty stomach, at least 30 minutes before or 2 hours after breakfast and dinner. Do not crush, chew, or break the tablet. Consistent daily intake at a fixed time is recommended. Symptom improvement may take up to 12 weeks.

• Side Effects: Common side effects include headache, dizziness, diarrhea, abnormal stools, nausea, vomiting, abdominal pain, ankle swelling (edema), and palpitations. Serious side effects to report immediately to a doctor include unusual bleeding or bruising, severe headache, chest pain, fast or irregular heartbeat, severe swelling of the arms or legs, and symptoms of severe infection.

• Precautions: CILADOC 50 TAB is generally not recommended for individuals with severe heart problems (especially congestive heart failure), uncontrolled blood pressure, kidney disease, liver disease, active stomach ulcers, or a history of stroke in the last six months. It may increase the risk of bleeding, particularly when taken with other blood thinners. Pregnant or breastfeeding women should consult their doctor as it's typically not recommended. Avoid consuming large quantities of grapefruit juice, as it may affect the medicine's efficacy. The medication may cause dizziness, so caution is advised when driving or operating machinery.

• Storage: Store CILADOC 50 TAB in a cool, dry place away from direct sunlight, at a temperature below 30°C. Keep it in its original packaging and out of the sight and reach of children.

CILADOC 50 TAB contains Cilostazol, a medication primarily used to alleviate symptoms of intermittent claudication. Below are frequently asked questions regarding this medicine.

What is CILADOC 50 TAB used for?

CILADOC 50 TAB is primarily used to treat the symptoms of intermittent claudication, a condition characterized by pain, cramping, numbness, or fatigue in the legs that occurs during walking or exercise and improves with rest. This condition is caused by reduced blood flow to the legs due to narrowed arteries. It helps patients walk longer distances without pain by improving blood circulation in the legs.

How does CILADOC 50 TAB work?

CILADOC 50 TAB, containing Cilostazol, is a phosphodiesterase type 3 (PDE-3) inhibitor. It works by inhibiting PDE3 activity, which increases levels of cyclic adenosine monophosphate (cAMP) in platelets and blood vessels. This leads to two main effects: vasodilation (widening of blood vessels) and reduced platelet aggregation (decreased blood clotting activity), thereby enhancing blood flow to the legs.

What is the usual dosage for CILADOC 50 TAB?

The recommended dosage for Cilostazol is typically 100 mg twice daily. CILADOC 50 TAB, being 50mg, would generally be taken as two 50 mg tablets (total 100 mg) twice a day. It should be taken orally on an empty stomach, at least 30 minutes before or 2 hours after breakfast and dinner. If you are taking certain other medications that inhibit specific enzymes (like CYP3A4 or CYP2C19), your doctor may reduce the dose to 50 mg twice daily.

What are the possible side effects of CILADOC 50 TAB?

Common side effects include headache, diarrhea, abnormal stools, dizziness, heartburn, nausea, and abdominal pain. More serious side effects, which require immediate medical attention, can include fast or irregular heartbeat, unusual bleeding or bruising, swelling of the arms, hands, feet, ankles, or lower legs, and signs of heart failure (e.g., shortness of breath, sudden weight gain).

Is CILADOC 50 TAB safe during pregnancy or breastfeeding?

Cilostazol is generally not recommended during pregnancy as animal studies have shown potential risks, and adequate human studies are not available. For breastfeeding mothers, its use is also not recommended as it's unknown if Cilostazol passes into breast milk and could harm a nursing baby. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can CILADOC 50 TAB be taken with other medications?

CILADOC 50 TAB can interact with several medications. It is metabolized by liver enzymes (CYP3A4 and CYP2C19), so drugs that inhibit these enzymes (e.g., erythromycin, diltiazem, ketoconazole, omeprazole) can increase Cilostazol levels, potentially requiring a dose reduction to 50 mg twice daily. Concomitant use with other antiplatelet agents (like aspirin or clopidogrel) or anticoagulants (like warfarin) can increase the risk of bleeding. Grapefruit juice should be avoided as it can also increase Cilostazol concentration and the risk of side effects.

What precautions should be taken while using CILADOC 50 TAB?

CILADOC 50 TAB is contraindicated in patients with heart failure of any severity due to a potential risk of decreased survival. It should also be used with caution in individuals with bleeding disorders, active pathological bleeding (e.g., bleeding ulcers), severe kidney or liver disease, or those at risk of low white blood cell or platelet counts. Smoking can reduce the effectiveness of Cilostazol. Cilostazol may cause dizziness, so caution is advised when driving or operating machinery.

What happens if a dose of CILADOC 50 TAB is missed?

If you miss a dose of CILADOC 50 TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should CILADOC 50 TAB be stored?

CILADOC 50 TAB should be stored at room temperature, typically between 15 and 30 degrees Celsius (59 and 86 degrees Fahrenheit), away from heat, moisture, and direct light. It should be kept in a closed container and out of the reach of children and pets. Do not use any medication past its expiration date.