Rivaflo 20 Mg Tablet (10 Tab)

RIVAFLO 20 MG TABLET

RIVAFLO 20 MG TABLET, manufactured by SUN PHARMA LABORATORIES LTD., is an anticoagulant medication commonly known as a blood thinner. It helps to prevent and treat blood clots in various parts of the body, reducing the risk of serious cardiovascular events.

Composition

• Active Ingredient: Rivaroxaban 20 mg.

Uses

RIVAFLO 20 MG TABLET is primarily used for the following conditions:

• Treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE), which are blood clots in the legs and lungs, respectively.
• Reduction of stroke and systemic embolism risk in patients with non-valvular atrial fibrillation (irregular heartbeat).
• Prevention of blood clots in individuals who have undergone knee or hip replacement surgeries.
• Reduction of major cardiovascular events in patients with coronary artery disease (CAD) or peripheral artery disease (PAD) when used with aspirin.

Dosage and Administration

RIVAFLO 20 MG TABLET should be taken exactly as prescribed by a doctor. It can be taken with or without food, but taking it at the same time each day is recommended for maximum benefits. For doses of 15 mg or more, it is recommended to take it with food. Do not stop taking the medicine or change the dose without consulting your doctor, as this can increase the risk of blood clots. If a dose is missed, take it as soon as possible on the same day, but do not double the dose.

Side Effects

Common side effects include:

• Bleeding (e.g., nosebleeds, gum bleeding, unusual bruising, blood in urine or stools).
• Nausea.
• Low red blood cell count (anemia), leading to weakness, tiredness, or paleness.
• Dizziness and headache.
• Fatigue and peripheral edema (swelling in limbs).

Serious side effects, though less common, can include severe or uncontrollable bleeding, internal bleeding, and allergic reactions.

Precautions

• Bleeding Risk: RIVAFLO 20 MG TABLET increases the risk of bleeding. Inform your doctor about any bleeding problems or if you notice unusual bleeding.
• Allergies: Do not take if allergic to Rivaroxaban or any other ingredients.
• Pregnancy and Breastfeeding: Not recommended during pregnancy and generally considered unsafe during breastfeeding, as it may pass into breast milk.
• Medical Conditions: Use with caution in patients with liver disease, kidney disease, stomach ulcers, high blood pressure, or prosthetic heart valves.
• Interactions: Inform your doctor about all other medicines, supplements, or herbal preparations you are taking, especially other blood thinners, certain antifungal medicines (e.g., fluconazole, itraconazole), antibiotics (e.g., clarithromycin), HIV medications (e.g., ritonavir), and some painkillers (e.g., ibuprofen). Avoid grapefruit or grapefruit juice.
• Alcohol: Avoid or limit alcohol consumption as it may increase the risk of bleeding.
• Surgery: You may be asked to stop taking RIVAFLO 20 MG TABLET temporarily before surgery or dental treatment.

Storage

Store in a cool and dry place, away from sunlight and moisture. Keep out of sight and reach of children. Optimal storage is typically between 10ºC and 25ºC or below 30ºC.

RIVAFLO 20 MG TABLET contains Rivaroxaban as its active ingredient, which is an anticoagulant medication, commonly referred to as a blood thinner.

What is RIVAFLO 20 MG TABLET used for?

RIVAFLO 20 MG TABLET is primarily used to prevent and treat blood clots in various parts of the body. This includes treating deep vein thrombosis (DVT), which are blood clots typically in the leg veins, and pulmonary embolism (PE), which are blood clots in the lungs. It is also prescribed to reduce the risk of stroke and systemic embolism in adults with non-valvular atrial fibrillation (an irregular heartbeat). Additionally, it can be used to prevent DVT and PE after hip or knee replacement surgery, and in acutely ill patients at risk of clot formation. When combined with aspirin, it helps lower the risk of heart attack, stroke, or death in adults with coronary artery disease or peripheral arterial disease.

How does RIVAFLO 20 MG TABLET work?

RIVAFLO 20 MG TABLET works by blocking the action of Factor Xa, a specific protein involved in the blood clotting process. By inhibiting Factor Xa, Rivaroxaban reduces the production of thrombin, thereby preventing blood clots from forming. This mechanism helps to thin the blood and reduce the risk of clot-related complications.

What is the usual dosage for RIVAFLO 20 MG TABLET?

The dosage of RIVAFLO 20 MG TABLET (Rivaroxaban) depends on the condition being treated. For prevention of stroke in non-valvular atrial fibrillation, the typical adult dose is 20 mg once daily, taken with the evening meal. For the initial treatment of deep vein thrombosis (DVT) or pulmonary embolism (PE), the dose may start with 15 mg twice a day with food for the first 21 days, followed by 20 mg once a day with food. For continued prevention of DVT or PE after initial treatment, 20 mg once daily is common. It is crucial to take the medication exactly as prescribed by your healthcare provider, often with food, and preferably at the same time each day for optimal effectiveness. If you have kidney disease, your doctor may prescribe a lower dose.

What are the possible side effects of RIVAFLO 20 MG TABLET?

The most common and serious side effect of RIVAFLO 20 MG TABLET (Rivaroxaban) is bleeding, which can range from mild to severe. You may bruise or bleed more easily, experiencing heavier or longer periods, occasional nosebleeds, or bleeding gums. Other common side effects include headache, nausea, and stomach pain. Less common but serious side effects can include severe bleeding (e.g., bloody or black, tar-like stools, vomiting blood), allergic reactions (skin rash, itching, swelling), and in rare cases, liver problems or kidney dysfunction. If you experience any unusual or severe bleeding, or symptoms like severe headache, confusion, dizziness, or numbness, contact your doctor immediately.

Is RIVAFLO 20 MG TABLET safe during pregnancy or breastfeeding?

RIVAFLO 20 MG TABLET (Rivaroxaban) should generally not be taken during pregnancy. If you are pregnant, planning to become pregnant, or become pregnant while taking this medication, you should speak to your doctor immediately, as a different medicine may be necessary due to potential fetal side effects like bleeding. Regarding breastfeeding, Rivaroxaban gets into breast milk in very small amounts, and based on limited evidence, no side effects have been observed in infants after exposure through breast milk. However, due to limited information, your doctor may recommend an alternative medication or advise monitoring your baby for any possible side effects such as unusual bruising or feeding issues.

Can RIVAFLO 20 MG TABLET be taken with other medications?

RIVAFLO 20 MG TABLET (Rivaroxaban) can interact with other medications, potentially increasing the risk of bleeding. It is important to inform your doctor about all prescription and nonprescription medications, vitamins, and herbal supplements you are taking or plan to take. Specifically, avoid taking other anticoagulants (blood thinners like warfarin or enoxaparin), aspirin, or non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, unless advised by your doctor, as these can significantly increase the risk of bleeding. Certain medications for fungal or bacterial infections (e.g., fluconazole, erythromycin), HIV (e.g., ritonavir), and epilepsy (e.g., carbamazepine, phenytoin) can also affect how rivaroxaban works. St. John's wort, an herbal remedy, can decrease the effectiveness of Rivaroxaban and should be avoided.

What precautions should be taken while on RIVAFLO 20 MG TABLET?

While taking RIVAFLO 20 MG TABLET, it is important for your doctor to monitor your progress regularly. You may bleed or bruise more easily, so avoid activities that could cause injury. Be careful with sharp objects, use an electric razor, and take care when brushing or flossing your teeth. Inform any doctor or dentist treating you that you are taking this medicine. Avoid consuming grapefruit or grapefruit juice as it may increase the risk of side effects. Limit or avoid alcohol, as heavy drinking can increase bleeding risk. If you have kidney or liver disease, bleeding problems, or antiphospholipid syndrome (APS), your doctor may need to adjust your dose or consider alternative treatments. Inform your doctor about any planned surgeries, dental work, or spinal procedures, as you may need to temporarily stop the medication. Carry a medical ID card or bracelet indicating you are taking an anticoagulant.

What happens if a dose of RIVAFLO 20 MG TABLET is missed?

If you miss a dose of RIVAFLO 20 MG TABLET (20 mg, once daily dosing), take it as soon as you remember on the same day. Do not take more than one dose in a single day. If it is almost time for your next dose (e.g., less than 12 hours until the next scheduled dose), skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. It is crucial not to stop taking Rivaroxaban without consulting your doctor, as this can increase your risk of blood clots or stroke.

How should RIVAFLO 20 MG TABLET be stored?

RIVAFLO 20 MG TABLET should be stored in a closed container at room temperature, away from heat, moisture, and direct light. Keep it out of the reach of children. Do not keep outdated medicine or medicine no longer needed, and ask your healthcare professional how to properly dispose of any unused medication. It should be protected from moisture and light.