Silofast D 8 Mg Capsule (10 Cap)

SILOFAST D 8 MG CAPSULE

SILOFAST D 8 MG CAPSULE is a medication manufactured by CIPLA LTD. It is a combination therapy designed to address symptoms associated with benign prostatic hyperplasia (BPH) in adult men.

Composition

Each capsule contains:

• Silodosin: 8 mg
• Dutasteride: 0.5 mg

Uses

SILOFAST D 8 MG CAPSULE is primarily used to treat the signs and symptoms of benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland in men. It helps to improve urine flow, reduce frequent or urgent urination, alleviate discomfort, and decrease the risk of acute urinary retention and BPH-related surgery. Silodosin relaxes muscles in the prostate and bladder neck, while Dutasteride helps shrink the prostate by lowering hormone levels.

Dosage and Administration

Typically, one capsule of SILOFAST D 8 MG should be taken orally once daily, approximately 30 minutes after the same meal each day. The capsule should be swallowed whole with a glass of water, without crushing, chewing, or opening it. Always follow your doctor's prescribed dosage and duration.

Side Effects

Common side effects may include:

• Dizziness, headache
• Ejaculation disorders (e.g., decreased libido, impotence, retrograde ejaculation)
• Nasal congestion
• Diarrhea, nausea, abdominal pain
• Breast tenderness and enlargement in males

Serious side effects are less common but require medical attention.

Precautions

• Pregnancy: Contraindicated for women, especially those pregnant or planning to conceive, as Dutasteride may cause fetal harm.
• Liver/Kidney Impairment: Avoid use in severe liver or kidney disease. Use with caution in moderate cases.
• Orthostatic Hypotension: May cause dizziness or low blood pressure upon standing; caution advised when driving or operating machinery.
• Cataract Surgery: Inform your ophthalmologist about taking this medication before cataract surgery.
• Drug Interactions: Concomitant use with other alpha-blockers, antihypertensives, strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir), and PDE5 inhibitors can increase the risk of adverse effects.
• Blood Donation: Men taking this medicine should not donate blood for at least 6 months after the last dose.
• Alcohol: Avoid or limit alcohol consumption as it may increase dizziness.

Storage

Store below 30°C in a cool, dry place. Protect from light and moisture, and keep out of reach of children and pets.

What is Silofast D 8 mg Capsule used for?

Silofast D 8 mg Capsule is primarily used to treat benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland in men. It helps to alleviate urinary symptoms associated with BPH, such as difficulty in urination, frequent or urgent urination (especially at night), a weak or interrupted urine flow, and the feeling of incomplete bladder emptying. This medication can also reduce the risk of acute urinary retention and the need for BPH-related surgery.

How does Silofast D 8 mg Capsule work?

Silofast D 8 mg Capsule contains two active ingredients: Silodosin (8 mg) and Dutasteride (0.5 mg). Silodosin is an alpha-1 blocker that works by relaxing the muscles in the prostate, bladder neck, and urethra, which improves urine flow and reduces urinary symptoms. Dutasteride is a 5-alpha-reductase inhibitor that works by reducing the production of dihydrotestosterone (DHT), a hormone responsible for prostate growth, thereby gradually shrinking the size of the enlarged prostate.

What is the usual dosage of Silofast D 8 mg Capsule?

The usual adult dose is one Silofast D 8 mg Capsule taken once daily with a meal. It should be swallowed whole with a glass of water and not crushed, chewed, or opened. It's important to take the medicine at the same time each day to maintain consistent levels in the body and for optimal results, and to continue the medication for the duration prescribed by your doctor.

What are the possible side effects of Silofast D 8 mg Capsule?

Common side effects of Silofast D 8 mg Capsule include dizziness, headache, decreased libido (sex drive), impotence (difficulty achieving an erection), ejaculation disorders (such as retrograde ejaculation where semen goes into the bladder), breast tenderness and enlargement, nasal congestion, and diarrhea. More serious, but less common, side effects can include severe low blood pressure, breast changes, and painful erections. If side effects persist or worsen, consult your doctor.

Is Silofast D 8 mg Capsule safe during pregnancy or breastfeeding?

No, Silofast D 8 mg Capsule is contraindicated during pregnancy and for women who are breastfeeding. The Dutasteride component can harm a developing fetus, particularly male fetuses, by affecting the development of male reproductive organs. It is also not known if it passes into breast milk. This medication is intended for men only and should not be used by women or children.

Can Silofast D 8 mg Capsule be taken with other medications?

Silofast D 8 mg Capsule can interact with several medications. Concomitant use with other alpha-blockers (e.g., tamsulosin, terazosin) or antihypertensive medications (e.g., amlodipine, lisinopril) can increase the risk of low blood pressure (hypotension), dizziness, and fainting. Strong CYP3A4 inhibitors, such as ketoconazole, itraconazole, ritonavir, and cyclosporine, can significantly increase the levels of silodosin in the body, potentially leading to increased side effects. It is crucial to inform your doctor about all medications, herbal preparations, and supplements you are currently taking to avoid potential interactions.

What precautions should be taken while using Silofast D 8 mg Capsule?

Precautions include:

• Driving and Operating Machinery: This medicine may cause dizziness or fainting, especially when starting treatment. Exercise caution when driving or performing hazardous tasks.
• Blood Pressure: Be cautious if you have low blood pressure, as the medication can further lower it. Rise slowly from a sitting or lying position to prevent dizziness.
• Liver and Kidney Conditions: Avoid use if you have severe liver or kidney disease. Consult your doctor if you have mild to moderate impairment.
• Alcohol Consumption: It is advisable to limit or avoid alcohol consumption as it can increase the risk of side effects like dizziness and low blood pressure.
• Blood Donation: Men taking Silofast D 8 mg Capsule should not donate blood for at least 6 months after their last dose to prevent exposure to pregnant women through blood transfusions.
• Cataract Surgery: Inform your ophthalmologist before undergoing cataract surgery if you are using this medication.

What happens if a dose of Silofast D 8 mg Capsule is missed?

If you miss a dose, take it as soon as you remember, preferably after a meal on the same day. However, if it's already close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for a missed dose.

How should Silofast D 8 mg Capsule be stored?

Silofast D 8 mg Capsule should be stored below 30°C in a cool and dry place, protected from moisture and light. Keep it out of the reach of children and pets.