Fenolip 145 Tab

FENOLIP 145 Tablet

Name

Brand Name: FENOLIP 145 Tablet Common Name: Fenofibrate

Composition

Each FENOLIP 145 tablet contains Fenofibrate 145 mg. Fenofibrate is a lipid-lowering medication.

Uses

FENOLIP 145 Tablet is primarily used to manage high cholesterol and high triglyceride levels in the blood. It works by reducing "bad" cholesterol (LDL) and triglycerides, while simultaneously increasing "good" cholesterol (HDL). This action helps to lower the risk of heart attack, stroke, and other cardiovascular diseases by reducing fat buildup in arteries. It is also indicated as an adjunctive therapy to diet for adults with primary hypercholesterolemia or mixed dyslipidemia, and severe hypertriglyceridemia. Additionally, it can be used to manage lipid abnormalities in patients with type 2 diabetes.

Dosage and Administration

The typical initial dose of FENOLIP 145 Tablet is 145 mg once daily. It should be taken with food and a glass of water, and swallowed whole without crushing or chewing. Dosage should be individualized by a physician based on patient response and adjusted if necessary, with lipid levels re-evaluated at 4- to 8-week intervals.

Side Effects

Common Side Effects:

• Muscle pain or weakness
• Diarrhea
• Abdominal pain
• Nausea and vomiting
• Headache
• Flatulence
• Increased liver enzymes
• Back pain
• Inflammation of the nose
• Increased creatine phosphokinase (CPK) levels

Serious Side Effects:

• Kidney damage (rare)
• Rhabdomyolysis (breakdown of muscle tissues)
• Increase in serum creatinine levels

Precautions

FENOLIP 145 Tablet is not recommended for use during pregnancy or breastfeeding. Alcohol consumption should be avoided as it may increase the risk of side effects and liver damage. Caution is advised for patients with liver disease, severe kidney impairment, or gallbladder conditions such as gallstones. It is not recommended for children under 18 years of age. Patients should report any unexplained muscle pain, tenderness, or weakness, especially if accompanied by fever, to their doctor promptly. Interactions can occur with coumarin anticoagulants (requiring careful monitoring of PT/INR) and glitazones.

Storage

Store FENOLIP 145 Tablet in a cool, dry place, below 20-25°C or below 30°C. Protect it from light and moisture, and keep it out of the reach and sight of children.

FENOLIP 145 TAB is a medication containing Fenofibrate 145 mg, primarily used to manage high levels of cholesterol and triglycerides in the blood. This medication helps to reduce the risk of cardiovascular events such as heart attacks and strokes.

Here are some frequently asked questions about FENOLIP 145 TAB:

What is FENOLIP 145 TAB used for?

FENOLIP 145 TAB is used to treat high levels of cholesterol and triglycerides (fats) in the blood. It is prescribed for conditions like primary hypercholesterolemia, mixed dyslipidemia, and severe hypertriglyceridemia, often as an adjunctive therapy to diet and exercise. By lowering these harmful fats, it helps reduce the risk of clogged arteries, heart attacks, and strokes.

How does FENOLIP 145 TAB work?

The active ingredient, fenofibrate, is a lipid-lowering medicine. It works by activating peroxisome proliferator-activated receptor alpha (PPARα), which increases the breakdown of fats in the body. This mechanism leads to a reduction in triglycerides and LDL ("bad" cholesterol) and an increase in HDL ("good" cholesterol) levels in the blood.

What is the usual dosage of FENOLIP 145 TAB?

For conditions like hypercholesterolemia or mixed dyslipidemia, the typical dosage is 145 mg once daily. For severe hypertriglyceridemia, the initial dose can range from 48 to 145 mg per day, which may be adjusted by your doctor based on your response. It is generally recommended to take this medicine with food to increase its absorption.

What are the possible side effects of FENOLIP 145 TAB?

Common side effects can include stomach discomfort, nausea, vomiting, diarrhea, flatulence, headache, back pain, and a stuffy nose. More serious but less common side effects can involve muscle pain, tenderness, or weakness (myopathy or rhabdomyolysis), kidney damage, gallstones, pancreatitis, and blood clots. If you experience severe muscle pain or unexplained weakness, you should seek medical advice immediately.

Is FENOLIP 145 TAB safe during pregnancy or breastfeeding?

FENOLIP 145 TAB is generally not recommended during pregnancy due to limited information regarding its safe use and potential risks to the fetus. Similarly, it is advised to avoid FENOLIP 145 TAB while breastfeeding because fenofibrate may pass into breast milk and could potentially affect the infant's lipid metabolism. The manufacturer recommends against breastfeeding during treatment and for 5 days after the last dose.

Can FENOLIP 145 TAB be taken with other medications?

FENOLIP 145 TAB can interact with several medications. Concomitant use with blood thinners like warfarin can increase the risk of bleeding. Taking it with immunosuppressants such as cyclosporine may increase the risk of kidney problems. When used with other fat-lowering medications, particularly statins, there is an increased risk of muscle damage. Oral contraceptives may also reduce the effects of fenofibrate. Always inform your doctor about all medications, supplements, and herbal products you are taking.

What precautions should be taken while using FENOLIP 145 TAB?

This medicine is not recommended for individuals with severe liver or kidney disease, or gallbladder disease. Regular monitoring of liver and kidney function is advised during treatment. It is important to report any unusual muscle pain or weakness to your doctor promptly. Avoiding alcohol intake is also recommended to achieve better control of fat levels and prevent liver issues. Maintaining a healthy lifestyle, including a low-fat diet and regular exercise, is crucial.

What happens if a dose of FENOLIP 145 TAB is missed?

If you miss a dose of FENOLIP 145 TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should FENOLIP 145 TAB be stored?

FENOLIP 145 TAB should be stored in a cool, dry place, away from direct sunlight and moisture. Keep the tablets in their original packaging and out of the reach of children and pets. The recommended storage temperature is typically below 20-25°C or 30°C.