ROZUSTAT 10 TABLET

Name:

• Common Name: Rosuvastatin 10 mg Tablet
• Brand Name: ROZUSTAT 10 TABLET

Composition: Each tablet contains Rosuvastatin (as calcium) equivalent to 10 mg of Rosuvastatin. It belongs to a class of drugs called statins.

Uses: ROZUSTAT 10 TABLET is primarily used to manage high blood cholesterol and triglyceride levels. It works by blocking an enzyme in the liver responsible for cholesterol production, thereby reducing "bad" cholesterol (LDL and triglycerides) and increasing "good" cholesterol (HDL). This medication is prescribed to:

• Lower LDL cholesterol and triglycerides in the blood.
• Increase HDL cholesterol.
• Reduce the risk of cardiovascular diseases, including heart attacks and strokes.
• Slow down the progression of atherosclerosis (narrowing of blood vessels due to fat build-up).
• Treat familial hypercholesterolemia in children aged eight years or more.

Dosage and Administration:

• ROZUSTAT 10 TABLET is typically taken once daily.
• It can be taken with or without food, at any time of the day, but it is recommended to take it at a fixed time daily for consistency.
• Tablets should be swallowed whole and not chewed, crushed, or broken.
• Dosage is determined by a physician based on the patient's medical condition and response to the medicine.

Side Effects: Common side effects include:

• Muscle pain (myalgia), weakness, or fatigue (asthenia)
• Headache
• Nausea, abdominal pain, or stomach upset
• Constipation
• Daytime drowsiness

Serious side effects (rare) may include:

• Liver damage
• Rhabdomyolysis (severe muscle breakdown) with potential kidney damage
• Cognitive impairment (memory loss, confusion)

Precautions:

• Allergies: Do not take if allergic to rosuvastatin or any ingredients.
• Liver Disease: Contraindicated in patients with active liver disease or unexplained elevated liver enzymes. Regular liver enzyme tests are recommended.
• Pregnancy and Breastfeeding: Not recommended for pregnant or breastfeeding women as it may harm the developing baby.
• Kidney Problems: Use with caution; dose adjustment may be required.
• Diabetes: Monitor blood sugar levels regularly, as it may cause an increase.
• Alcohol: Avoid excessive alcohol intake as it may increase the risk of liver problems and other side effects.
• Drug Interactions: Inform your doctor about all medicines, supplements, or herbals being taken, especially blood thinners (e.g., warfarin), immune suppressants (cyclosporine), anti-HIV medicines, anti-fungal medicines (fluconazole), and other cholesterol-lowering drugs (e.g., gemfibrozil).
• Muscle Disorders: Use with caution if there is a history of myopathy or rhabdomyolysis; report unusual muscle pain, tenderness, or weakness.

Storage: Store in a cool and dry place, below 30°C, away from direct sunlight and moisture. Keep out of the sight and reach of children.

Frequently Asked Questions about ROZUSTAT 10 TABLET

What is Rozustat 10 Tablet used for?

Rozustat 10 Tablet is primarily used to lower high cholesterol and triglyceride levels in the blood. It helps reduce "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL). By doing so, it helps prevent the build-up of fatty deposits in blood vessels, significantly reducing the risk of heart attacks and strokes. It can also be used to slow the progression of atherosclerosis (narrowing of blood vessels) and in children aged eight years or more with familial hypercholesterolemia.

How does Rozustat 10 Tablet work?

Rozustat 10 Tablet contains Rosuvastatin, which belongs to a class of medicines called statins. It works by blocking an enzyme in the liver called HMG-CoA reductase, which is essential for cholesterol production. By inhibiting this enzyme, Rozustat 10 Tablet reduces the amount of cholesterol the body produces and increases the liver's ability to remove existing "bad" cholesterol from the blood.

What is the usual dosage of Rozustat 10 Tablet?

Rozustat 10 Tablet is typically taken once a day. It can be taken with or without food, at any time of the day, but it is recommended to take it at the same time daily to help with consistency. Your doctor will determine the appropriate dose based on your health condition and response to the medicine.

What are the possible side effects of Rozustat 10 Tablet?

Common side effects may include muscle pain (myalgia), headache, nausea, abdominal pain, weakness (asthenia), and daytime drowsiness. These are usually mild and temporary. More serious, though rare, side effects can include severe muscle problems like myopathy or rhabdomyolysis (muscle breakdown that can lead to kidney damage), liver problems, and a slight increase in blood sugar levels. If you experience persistent or concerning side effects such as unexplained muscle pain, tenderness, weakness, dark-colored urine, or yellowing of the eyes or skin, consult your doctor immediately.

Is Rozustat 10 Tablet safe during pregnancy or breastfeeding?

No, Rozustat 10 Tablet is considered unsafe during pregnancy and is contraindicated for pregnant women or those planning a pregnancy, as it can harm the developing baby. Women of childbearing age should use effective contraceptive methods while taking this medicine. It is also not recommended during breastfeeding, as the active component may pass into breast milk and cause side effects in the infant.

Can Rozustat 10 Tablet be taken with other medications?

Rozustat 10 Tablet can interact with certain other medications, potentially leading to increased risk of side effects like muscle damage. It's important to inform your doctor about all medicines, supplements, or herbal products you are currently taking. Particular caution is advised with immune system affecting medicines (like cyclosporine), anti-HIV medicines (lopinavir, ritonavir, atazanavir), blood thinners (anticoagulants like warfarin), certain antibiotics (like fusidic acid), and other cholesterol-lowering medicines (such as gemfibrozil).

What precautions should be taken with Rozustat 10 Tablet?

Before taking Rozustat 10 Tablet, inform your doctor if you have kidney problems, liver disease (it is not recommended for those with severe liver disease), diabetes, thyroid problems (hypothyroidism), severe lung disease, or a history of muscle disorders. Regular monitoring of liver function and blood sugar levels may be advised. Avoid excessive alcohol consumption as it can increase the risk of liver damage. It is part of a comprehensive treatment plan that should include a healthy, low-fat diet, regular exercise, and weight management.

What happens if a dose of Rozustat 10 Tablet is missed?

If you miss a dose of Rozustat 10 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Rozustat 10 Tablet be stored?

Rozustat 10 Tablet should be stored in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. It should be kept at temperatures not exceeding 30°C.