Triolmesar Ch 20 Mg (15tab)

TRIOLMESAR CH 20 Tablet

TRIOLMESAR CH 20 Tablet is a combination medication manufactured by Macleods Pharmaceuticals Ltd. used to manage hypertension, commonly known as high blood pressure. This medication helps to reduce the risk of serious cardiovascular events such as heart attack and stroke.

Composition

Each TRIOLMESAR CH 20 Tablet contains three active ingredients:

• Olmesartan Medoxomil: 20 mg (an angiotensin II receptor blocker)
• Amlodipine: 5 mg (a calcium channel blocker)
• Chlorthalidone: 12.5 mg (a thiazide diuretic)

These ingredients work synergistically to relax and widen blood vessels, improve blood flow, and increase the removal of excess water and salts from the body, thereby lowering blood pressure.

Uses

TRIOLMESAR CH 20 Tablet is prescribed for:

• Management of hypertension (high blood pressure)
• Reducing the risk of heart attack and stroke
• Managing heart failure
• Protecting kidney function in diabetic patients with hypertension
• Reducing edema (fluid retention)

Dosage and Administration

TRIOLMESAR CH 20 Tablet is typically taken orally once daily, with or without food. It is advisable to take the medicine at the same time each day to maintain consistent blood levels. Due to its diuretic component, it is best to avoid taking this medicine within four hours of going to bed to prevent increased urination disrupting sleep. The tablet should be swallowed whole and not chewed, crushed, or broken. It is crucial to continue taking the medication as prescribed by your doctor, even if you feel well, as high blood pressure often has no noticeable symptoms.

Side Effects

Common side effects may include:

• Headache, dizziness, tiredness, weakness, sleepiness, flushing
• Ankle swelling
• Nausea, vomiting, stomach pain, constipation, diarrhea, indigestion
• Sore throat, runny nose, cough, flu-like symptoms, urinary tract infections
• Back pain, joint pain, muscle pain
• Changes in taste, blurred vision
• Alterations in blood tests such as high blood uric acid levels, low blood sodium or magnesium levels, high or low blood sugar levels, high blood potassium levels, and increased blood cholesterol and liver enzymes.
• Low blood pressure, which may cause dizziness upon standing, and impotence in men.

Serious but rare side effects can include severe allergic reactions, severe skin reactions, kidney problems, electrolyte imbalances, chest pain, and inflammation of the pancreas.

Precautions

• Pregnancy and Breastfeeding: TRIOLMESAR CH 20 Tablet is not recommended during pregnancy as it may harm the fetus, nor during breastfeeding as it may pass into breast milk.
• Alcohol Consumption: Avoid alcohol while taking this medicine, as it can increase the risk of low blood pressure and enhance dizziness or drowsiness.
• Driving and Operating Machinery: Do not drive or operate heavy machinery if you experience dizziness or drowsiness.
• Kidney and Liver Conditions: Use with caution in patients with kidney or liver problems. It is not recommended for those with severe liver or kidney disease. Close monitoring of kidney function is advised.
• Heart Conditions: Not recommended for patients with severe heart problems such as severe heart failure, aortic stenosis (narrowing of arteries), or cardiogenic shock. Use with caution if there is a history of recent heart attack, irregular heartbeat, or coronary heart disease.
• Electrolyte Imbalances: Inform your doctor if you have low sodium, potassium, or magnesium levels, or high blood calcium.
• Other Conditions: Disclose any history of diabetes, gout, kidney stones, Addison's disease, or dehydration to your doctor.
• Drug Interactions: Inform your doctor about all other medications you are taking, especially other antihypertensives, lithium, NSAIDs, and potassium supplements, as interactions may occur.
• Monitoring: Regular monitoring of blood pressure, kidney function, electrolyte levels, and blood sugar levels is recommended during treatment.

Storage

Store TRIOLMESAR CH 20 Tablet below 25°C. Keep it protected from moisture and direct sunlight, and out of the reach and sight of children.

TRIOLMESAR CH 20 MG (15TAB) is a combination medicine used to treat high blood pressure, also known as hypertension. It contains Olmesartan, Amlodipine, and Chlorthalidone as active ingredients.

What is TRIOLMESAR CH 20 MG used for?

TRIOLMESAR CH 20 MG is primarily used to manage hypertension (high blood pressure). It also helps to reduce the risk of cardiovascular events such as heart attacks and strokes, and can be beneficial in managing heart failure, stroke, and preventing kidney damage in diabetic patients. It can also help reduce fluid retention (edema) caused by some kidney or liver diseases.

How does TRIOLMESAR CH 20 MG work?

This medicine works through the combined action of its three active ingredients:

• Olmesartan (an Angiotensin II Receptor Blocker - ARB): Works by blocking a hormone called angiotensin II, which causes blood vessels to narrow. By blocking its action, olmesartan relaxes and widens blood vessels, making it easier for the heart to pump blood and reducing blood pressure.
• Amlodipine (a Calcium Channel Blocker): Relaxes and widens blood vessels by acting on muscle cells in the artery walls, improving blood flow and reducing the workload on the heart.
• Chlorthalidone (a Thiazide Diuretic, or "water pill"): Increases the excretion of excess water and salts (like sodium and potassium) from the body through urine. This reduces the fluid volume in the blood, thereby lowering blood pressure.

Together, these ingredients synergistically lower blood pressure by different mechanisms, providing a comprehensive approach to hypertension management.

What is the usual dosage for TRIOLMESAR CH 20 MG?

The dosage of TRIOLMESAR CH 20 MG depends on your specific condition and how you respond to the medication, and should be determined by your doctor. It is typically taken orally once daily, preferably in the mornings, with or without food. It is important to swallow the tablet whole and not to chew, crush, or break it. Consistency in taking the medicine at the same time each day is recommended to maintain stable blood levels.

What are the possible side effects of TRIOLMESAR CH 20 MG?

Common side effects may include headache, dizziness, tiredness, weakness, and ankle swelling. Other possible side effects can include high blood uric acid levels, low blood sodium or magnesium levels, high or low blood sugar levels, low blood pressure (which may cause dizziness upon standing), impotence in men, sore throat, runny nose, cough, flu-like symptoms, urinary tract infections, and increased blood cholesterol levels. Some people may also experience nausea, vomiting, stomach pain, constipation, diarrhea, indigestion, back pain, and joint pain. If any of these side effects persist or worsen, it's advisable to consult your doctor.

Is TRIOLMESAR CH 20 MG safe during pregnancy or breastfeeding?

TRIOLMESAR CH 20 MG is generally not recommended for use during pregnancy as it may cause serious harm to the developing fetus. It is also not recommended for use during breastfeeding as it may pass into breast milk and harm the nursing infant. It is crucial to consult your doctor for advice if you are pregnant, planning to become pregnant, or breastfeeding.

Can TRIOLMESAR CH 20 MG be taken with other medications?

Before taking TRIOLMESAR CH 20 MG, inform your doctor about all other medicines, supplements, or herbal products you are taking, especially other medications for high blood pressure or heart problems (e.g., atenolol, enalapril, amlodipine, nifedipine). Interactions can also occur with medicines used for fungal infections (ketoconazole, itraconazole), HIV infections (ritonavir), bacterial infections (rifampicin, erythromycin), muscle spasms (dantrolene), NSAIDs (like aspirin or ibuprofen), lithium, and potassium supplements. Avoid drinking grapefruit juice while on this medication, as it can further decrease blood pressure.

What precautions should be taken with TRIOLMESAR CH 20 MG?

• Inform your doctor if you have any liver or kidney problems, severe high or low blood pressure, heart problems (like narrowing of arteries, cardiogenic shock, recent heart attack, or issues with heart muscle/valves), diabetes, high blood cholesterol, dehydration, or very low blood sodium, potassium, or magnesium levels.
• Avoid alcohol consumption as it can increase dizziness and drowsiness and may lead to a further drop in blood pressure.
• Do not drive or operate heavy machinery if you experience dizziness, drowsiness, or blurred vision while taking this medicine.
• Regular monitoring of blood pressure, kidney function, electrolyte levels, and blood sugar is recommended during treatment.
• Avoid a low-salt diet unless advised by your doctor, as this may further reduce blood pressure.

What happens if a dose of TRIOLMESAR CH 20 MG is missed?

If you miss a dose of TRIOLMESAR CH 20 MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should TRIOLMESAR CH 20 MG be stored?

TRIOLMESAR CH 20 MG should be stored at room temperature (20-25°C) and protected from moisture and direct sunlight. Ensure it is kept out of reach of children and pets.