Tenglyn M 500 Tablet

TENGLYN M 500 TABLET

TENGLYN M 500 TABLET, manufactured by Zydus Cadila, is an anti-diabetic medication used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It can be prescribed alone or with other diabetes medications.

• Composition: Each tablet contains Metformin Hydrochloride (500 mg) and Teneligliptin (20 mg). Metformin is a biguanide that reduces glucose production in the liver, decreases intestinal glucose absorption, and improves insulin sensitivity. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases insulin levels and reduces glucagon levels in the body, especially after meals.

• Uses: TENGLYN M 500 TABLET is primarily used for the management of type 2 diabetes mellitus to improve glycemic control. This helps prevent serious complications such as kidney damage, blindness, nerve problems, and may reduce the risk of heart attack or stroke.

• Dosage and Administration: It is typically recommended to take TENGLYN M 500 TABLET once daily or as advised by a physician. The tablet should be swallowed whole with a glass of water, without crushing, chewing, or breaking it. Taking it with meals can help reduce stomach upset.

• Side Effects: Common side effects may include nausea, vomiting, diarrhea, headache, stomach ache, and hypoglycemia (low blood sugar level). Serious but rare side effects include lactic acidosis, which requires immediate medical attention if symptoms like severe abdominal pain, muscle cramps, or difficulty breathing occur.

• Precautions: Inform your doctor about any history of liver, kidney, or heart problems, severe infection, or if you are pregnant or breastfeeding. Excessive alcohol consumption should be avoided as it increases the risk of lactic acidosis. Long-term use may lead to Vitamin B12 deficiency.

• Storage: Store TENGLYN M 500 TABLET in a cool, dry place, away from direct sunlight, and out of the sight and reach of children. Store below 30°C.

Here are frequently asked questions about TENGLYN M 500 TABLET by ZYDUS CADILA, along with their concise answers:

What is TENGLYN M 500 TABLET used for?

TENGLYN M 500 TABLET is primarily used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is often prescribed when diet and exercise alone, or treatment with metformin alone, have not been sufficient to control blood sugar. This medication helps prevent serious complications of diabetes such as kidney damage, vision problems, and reduces the risk of heart attack or stroke.

How does TENGLYN M 500 TABLET work?

TENGLYN M 500 TABLET contains two active ingredients: Metformin and Teneligliptin. Metformin works by decreasing the amount of glucose produced by the liver, lowering the absorption of glucose from the intestines, and increasing the body's sensitivity to insulin. Teneligliptin, a DPP-4 inhibitor, increases the levels of insulin in the body and reduces the levels of glucagon (a hormone that raises blood sugar), especially after meals. Together, these actions help to effectively control blood sugar levels.

What is the usual dosage for TENGLYN M 500 TABLET?

The usual dosage for TENGLYN M 500 TABLET is typically once daily, or as advised by your doctor. It should be swallowed whole with a glass of water and not crushed, chewed, or broken. Taking it with food may help reduce stomach upset. Your doctor will determine the correct dose and duration of therapy based on your condition and blood sugar levels.

What are the possible side effects of TENGLYN M 500 TABLET?

Common side effects may include nausea, vomiting, diarrhea, headache, and stomach upset. Hypoglycemia (low blood sugar) can also occur, particularly if the medicine is taken with insulin or sulfonylureas, or if meals are skipped or alcohol is consumed. A rare but serious side effect is lactic acidosis, characterized by symptoms like abdominal pain, muscle cramps, severe fatigue, and difficulty breathing. Long-term use may also lead to Vitamin B12 deficiency.

Is TENGLYN M 500 TABLET safe during pregnancy or breastfeeding?

During pregnancy: Caution is advised, and it may be considered unsafe. It should only be used if the potential benefit justifies the potential risk to the fetus, and only after consulting your doctor. During breastfeeding: It is generally not recommended to use TENGLYN M 500 TABLET while breastfeeding as it may pass into breast milk and potentially harm the nursing baby. Safer alternatives should be discussed with your doctor.

Can TENGLYN M 500 TABLET be taken with other medications?

TENGLYN M 500 TABLET can interact with other medications, so it's crucial to inform your doctor about all medicines you are currently taking. For example, combining it with insulin or sulfonylureas can increase the risk of low blood sugar. Diuretics and certain blood pressure medications may increase the risk of lactic acidosis. Corticosteroids may reduce its blood sugar-lowering effect.

What precautions should be taken while using TENGLYN M 500 TABLET?

Inform your doctor if you have kidney, liver, or heart problems, severe infections, or are scheduled for surgery. Avoid or limit alcohol consumption, as it can increase the risk of lactic acidosis. Regular monitoring of blood sugar levels and kidney function is recommended during treatment. Be cautious while driving or operating machinery if you experience vision problems or symptoms of low blood sugar. This medicine is contraindicated in patients with severe kidney or liver impairment, type 1 diabetes, or a history of diabetic ketoacidosis.

What happens if a dose of TENGLYN M 500 TABLET is missed?

If you miss a dose of TENGLYN M 500 TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should TENGLYN M 500 TABLET be stored?

TENGLYN M 500 TABLET should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat, ideally below 30°C. Keep it in its original container and ensure it is kept out of the sight and reach of children.

Can long-term use of TENGLYN M 500 TABLET cause Vitamin B12 deficiency?

Yes, long-term use of TENGLYN M 500 TABLET, specifically due to the Metformin component, can potentially lead to Vitamin B12 deficiency. This deficiency may cause symptoms such as anemia and nerve problems, including tingling sensations or numbness in hands and feet, weakness, and difficulty with balance. If you experience these symptoms, consult your doctor, as they may recommend monitoring B12 levels and prescribe supplements if needed.