Empazio M 12.5/500mg Tab

EMPAZIO M 12.5/500MG Tablet

Name

• Brand Name: EMPAZIO M 12.5/500MG Tablet

Composition

• Active Ingredients: Each tablet contains Empagliflozin 12.5 mg and Metformin (as Metformin Hydrochloride) 500 mg.

Uses

EMPAZIO M 12.5/500MG Tablet is primarily used for the management of Type 2 Diabetes Mellitus in adults, alongside diet and exercise.

• It helps control high blood glucose (sugar) levels by removing excess sugar from the body through urine and by improving the body's sensitivity to insulin.
• It aids in preventing serious diabetes complications such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), and nerve damage (diabetic neuropathy).
• The medicine may also offer renal protection, slowing the progression of diabetic kidney disease, and can contribute to lowering blood pressure levels.
• It reduces the risk of cardiovascular events like heart attack and heart failure in patients with type 2 diabetes and pre-existing cardiovascular disease.

Dosage and Administration

• EMPAZIO M 12.5/500MG Tablet should be taken orally, usually once or twice daily, as directed by a doctor.
• It is generally recommended to take the tablet with meals to minimize stomach upset.
• To ensure optimal benefits, it should be taken at the same time each day.
• Do not stop taking the medicine abruptly without consulting a doctor, as this may lead to an increase in blood sugar levels and associated complications.

Side Effects

Common side effects may include:

• Frequent urination
• Urinary tract infections (UTIs)
• Genital fungal infections
• Nausea, vomiting, diarrhea, or stomach upset
• Hypoglycemia (low blood sugar), especially when used with other antidiabetic medicines, alcohol, or if meals are delayed or missed.

A serious but rare side effect is lactic acidosis, particularly with alcohol intake or overdose.

Precautions

• Allergies: Do not take if allergic to empagliflozin, metformin, or any other ingredients.
• Kidney and Liver Conditions: Not recommended for individuals with severe kidney or liver disease, Type 1 diabetes, or metabolic acidosis (e.g., lactic acidosis, diabetic ketoacidosis).
• Pregnancy and Breastfeeding: Generally unsafe during pregnancy and breastfeeding; consult a doctor to discuss risks and benefits.
• Alcohol Consumption: Avoid alcohol as it increases the risk of lactic acidosis and low blood sugar.
• Dehydration: Drinking plenty of fluids is advised to prevent dehydration.
• Other Medications: Inform your doctor about all other medications, supplements, or herbal products being taken to avoid potential interactions.
• Special Conditions: Caution is advised for elderly patients, those with severe infections, or those undergoing examinations with iodinated contrast agents.
• Driving: May affect alertness, vision, or cause sleepiness/dizziness, making driving unsafe.

Storage

• Store in a cool and dry place, away from direct sunlight.
• Keep the medicine below 30°C.
• Keep out of reach of children and pets.

EMPAZIO M 12.5/500MG TAB by TORRENT PHARMACEUTICALS LTD is a combination medication containing Empagliflozin (12.5mg) and Metformin (500mg), primarily used to manage Type 2 Diabetes Mellitus.

Here are some frequently asked questions about EMPAZIO M 12.5/500MG TAB:

1. What is EMPAZIO M 12.5/500MG TAB used for?

EMPAZIO M 12.5/500MG TAB is used to treat Type 2 Diabetes Mellitus in adults, alongside a healthy diet and exercise, to improve blood sugar control. It also helps reduce the risk of cardiovascular death, hospitalization for heart failure, and the progression of kidney disease in patients with Type 2 diabetes who also have established cardiovascular disease or chronic kidney disease. Additionally, it may contribute to weight management and lower blood pressure.

2. How does EMPAZIO M 12.5/500MG TAB work?

This medicine combines two active ingredients: Empagliflozin and Metformin. Empagliflozin works by blocking the sodium-glucose co-transporter-2 (SGLT-2) enzyme in the kidneys, which leads to the removal of excess sugar from the body through urine. Metformin reduces glucose production in the liver, decreases sugar absorption from the intestines, and enhances the body's sensitivity to insulin, helping it use insulin more effectively. Together, they more effectively lower blood glucose levels.

3. What is the usual dosage for EMPAZIO M 12.5/500MG TAB?

The dosage of EMPAZIO M 12.5/500MG TAB is determined by your doctor based on your medical condition and response to treatment. It is typically taken once or twice daily, preferably with meals, and at the same time each day for optimal benefit. The tablets should be swallowed whole with water and not chewed, crushed, or broken. Do not exceed the prescribed dose.

4. What are the possible side effects of EMPAZIO M 12.5/500MG TAB?

Common side effects may include frequent urination, mild skin rash, itchy skin, nausea, vomiting, diarrhea, stomach ache, loss of appetite, headache, and genital yeast infections or urinary tract infections (UTIs). More serious, but less common, side effects can include lactic acidosis (symptoms like unusual muscle pain, trouble breathing, stomach pain), dehydration, severe allergic reactions, ketoacidosis, and a rare but serious infection called Fournier's gangrene. There is also an increased risk of hypoglycemia (low blood sugar), especially when used with other diabetes medications, and a potential increased risk of lower limb amputation. Most common side effects often resolve over time, but you should consult your doctor if they persist or worsen.

5. Is EMPAZIO M 12.5/500MG TAB safe during pregnancy or breastfeeding?

EMPAZIO M 12.5/500MG TAB is generally not recommended and may be unsafe to use during pregnancy, especially in the second and third trimesters. If you are pregnant or planning to conceive, you should consult your doctor. It is also probably unsafe to use during breastfeeding, as its components may pass into breast milk. Your doctor will discuss the potential risks and benefits.

6. Can EMPAZIO M 12.5/500MG TAB be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, or herbal products you are currently taking or plan to take, as EMPAZIO M 12.5/500MG TAB can interact with some of them. The risk of low blood sugar (hypoglycemia) may increase if taken with insulin or insulin secretagogues (like sulfonylureas), which may require dose adjustments. It is generally not recommended to take this medicine with diuretics ("water pills") due to an increased risk of dehydration and low blood pressure. Certain medications for blood pressure or heart disease, as well as contrast agents used for X-rays or scans, may also interact.

7. What precautions should be taken while using EMPAZIO M 12.5/500MG TAB?

You should inform your doctor if you have kidney or liver problems, urinary tract infections, severe infections, uncontrolled diabetes, metabolic acidosis, dehydration, or a history of heart disease or pancreatitis. This medicine is not for individuals with Type 1 diabetes. Avoid consuming alcohol, as it can increase the risk of lactic acidosis and low blood sugar. Stay well-hydrated by drinking plenty of fluids. Regularly monitor your blood sugar levels and keep sugary food or juice handy to treat symptoms of hypoglycemia. Maintain good genital hygiene to help prevent fungal infections. Do not stop taking this medicine abruptly without consulting your doctor, as it can worsen blood sugar levels and increase the risk of diabetes complications.

8. What happens if a dose of EMPAZIO M 12.5/500MG TAB is missed?

If you miss a dose of EMPAZIO M 12.5/500MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. Consistent intake is important for managing blood sugar levels.

9. How should EMPAZIO M 12.5/500MG TAB be stored?

EMPAZIO M 12.5/500MG TAB should be stored in a cool and dry place, away from direct sunlight. Typically, it should be kept at temperatures between 10ºC to 25ºC or below 30ºC.