Flozen Plus Tab

FLOZEN PLUS TABLET

Flozen Plus Tablet is a combination medication manufactured by Mankind Pharma Ltd., designed to provide relief from pain, inflammation, and fever.

Composition Each tablet contains:

• Diclofenac (50mg)
• Paracetamol (325mg)
• Serratiopeptidase (15mg)

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking certain chemical messengers in the body. Paracetamol acts as an analgesic (pain reliever) and antipyretic (fever reducer). Serratiopeptidase is an enzyme that helps reduce swelling by breaking down abnormal proteins at the site of inflammation, promoting healing.

Uses Flozen Plus Tablet is prescribed for the short-term relief of various conditions, including:

• Mild to moderate pain
• Inflammation and swelling
• Muscle aches, back pain, and joint pain
• Pain associated with arthritis (osteoarthritis, rheumatoid arthritis, ankylosing spondylitis)
• Menstrual cramps (dysmenorrhea)
• Headaches and migraines
• Tooth pain and post-dental surgery pain
• Ear and throat pain
• Post-operative pain and swelling

Dosage and Administration Flozen Plus Tablet should be taken orally with food to minimize stomach upset. The dosage and duration of treatment are determined by a doctor based on the patient's condition and response to the medication. It is important to follow the doctor's prescription and not to exceed the recommended dose.

Side Effects Common side effects may include:

• Nausea and vomiting
• Stomach pain, indigestion, and heartburn
• Diarrhea or constipation
• Headache
• Dizziness and vertigo
• Loss of appetite

Serious side effects, though less common, can include skin rash, tinnitus, gastric/mouth ulcers, and increased liver enzymes. Patients experiencing persistent or worsening side effects should consult their doctor.

Precautions

• Alcohol: Avoid alcohol consumption as it may increase drowsiness, dizziness, and the risk of liver damage and stomach bleeding.
• Pregnancy and Breastfeeding: Flozen Plus Tablet is generally considered unsafe during pregnancy due to potential risks to the baby. Information on its use during breastfeeding is limited, and consultation with a doctor is advised.
• Driving: This medicine may cause dizziness and sleepiness, so caution is advised when driving or operating machinery.
• Pre-existing Medical Conditions: Inform your doctor about any history of kidney or liver problems, heart failure, high blood pressure, asthma, stomach ulcers, or bleeding disorders. Dose adjustments may be necessary for patients with liver or kidney impairment.
• Drug Interactions: Inform your doctor about all other medications you are taking to avoid potential interactions, especially other medicines containing paracetamol or NSAIDs.

Storage Store Flozen Plus Tablet in its original container, tightly closed, in a cool and dry place, as directed on the pack or label. Keep it out of reach of children and pets.

What is Flozen Plus Tablet used for?

Flozen Plus Tablet is primarily used to relieve pain, reduce inflammation, and decrease swelling associated with various conditions. It is effective for mild to moderate pain, including headaches, toothaches, menstrual cramps, muscle pain, back pain, and joint pain. It is also prescribed for conditions like arthritis (osteoarthritis, rheumatoid arthritis, ankylosing spondylitis), sprains, strains, and to manage post-operative inflammation and pain.

How does Flozen Plus Tablet work?

Flozen Plus Tablet is a combination of three active ingredients: Diclofenac, Paracetamol (Acetaminophen), and Serratiopeptidase.

• Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the action of cyclo-oxygenase (COX) enzymes, which are responsible for producing prostaglandins that cause pain, fever, and inflammation in the body.
• Paracetamol acts as an analgesic (pain reducer) and antipyretic (fever reducer). It primarily works in the central nervous system to increase the pain threshold and regulate body temperature, enhancing the pain-relief action.
• Serratiopeptidase is an enzyme that helps reduce swelling and inflammation. It works by breaking down abnormal proteins (like fibrin) at the site of injury or inflammation, facilitating fluid drainage and promoting healing.

What is the usual dosage for Flozen Plus Tablet?

The typical recommended dosage for adults is usually one tablet, twice daily. It should be swallowed whole with a glass of water, preferably with or after food, to help prevent stomach upset. Do not crush, break, or chew the tablet. Your doctor will determine the exact dosage and duration of treatment based on your medical condition and response. It is important not to exceed the recommended dose.

What are the possible side effects of Flozen Plus Tablet?

Common side effects may include nausea, stomach pain, loss of appetite, indigestion, stomach upset, diarrhea, and vomiting. Some individuals might also experience dizziness or drowsiness. If these side effects persist or worsen, you should consult your doctor. In rare cases, more serious side effects such as liver or kidney problems may occur, especially with prolonged use.

Is Flozen Plus Tablet safe during pregnancy or breastfeeding?

Flozen Plus Tablet is generally not recommended during pregnancy, especially in the last trimester, as NSAIDs can pose a risk to the developing baby. Information regarding its use during breastfeeding is limited, and it is generally not recommended for breastfeeding women. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medication.

Can Flozen Plus Tablet be taken with other medications?

It is crucial to inform your doctor about all medications you are currently taking, including over-the-counter drugs, herbal supplements, and dietary supplements. Flozen Plus Tablet may interact with:

• Other painkillers: Avoid taking it with other NSAIDs (like ibuprofen, naproxen, aspirin for pain relief) or other paracetamol-containing products, as this can increase the risk of side effects and potential toxicity.
• Blood thinners (anticoagulants): Such as warfarin, as the medicine may enhance their effects, increasing the risk of bleeding.
• Medicines for high blood pressure, anti-diabetic medicines, corticosteroids, and certain antibiotics (e.g., quinolones).
• Alcohol should be avoided during treatment as it can increase the risk of liver damage and other side effects like dizziness and stomach bleeding.

What precautions should be taken while using Flozen Plus Tablet?

Before taking Flozen Plus Tablet, inform your doctor if you have allergies to its ingredients or other NSAIDs (like aspirin). It should be used with caution or avoided in patients with a history of stomach ulcers, gastric bleeding, severe heart failure, or liver or kidney disease. Do not self-medicate or exceed the prescribed dose or duration of treatment. It is not recommended for use in children without a doctor's advice. Regular monitoring of kidney and liver function may be advised during prolonged treatment.

What happens if a dose of Flozen Plus Tablet is missed?

If you miss a dose of Flozen Plus Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Flozen Plus Tablet be stored?

Flozen Plus Tablet should be stored in a cool, dry place, away from direct sunlight and moisture. Keep the medication in its original container, tightly closed, and out of the reach of children.