Volibo R 0.2/1tablet

VOLIBO R 0.2/1 TABLET

Name:

• Brand Name: VOLIBO R 0.2/1 TABLET
• Manufacturer: SUN PHARMA LABORATORIES LTD.

Composition: Each tablet contains:

• Voglibose: 0.2 mg
• Repaglinide: 1 mg

Uses: VOLIBO R 0.2/1 TABLET is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is used when diet, exercise, and single-agent anti-diabetic medications like voglibose or repaglinide alone are insufficient to control blood sugar levels. This combination medicine is particularly effective in controlling post-meal blood glucose spikes (postprandial hyperglycemia). By improving glycemic control, it helps prevent long-term complications associated with diabetes, such as kidney damage, blindness, nerve problems, and loss of limbs.

Dosage and Administration: The dosage and duration of treatment are determined by the physician based on the patient's individual needs and response to therapy.

• Typically, the tablet is taken orally before or just after main meals, usually 15 to 30 minutes prior.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• It is important not to skip meals after taking this medicine.
• Always follow your doctor's instructions and do not adjust the dose without consultation.

Side Effects: Common side effects may include:

• Hypoglycemia (low blood sugar), which can manifest as sweating, dizziness, confusion, headache, and tremors.
• Abdominal pain, stomach pain.
• Diarrhea, flatulence, nausea.
• Headache, dizziness, fatigue.
• Arthralgia (joint pain), back pain.
• Skin rash.

Consult your doctor if any of these side effects persist or worsen.

Precautions:

• Pregnancy: Avoid during pregnancy as it may cause harm to the unborn baby. Monitoring is required if use is unavoidable.
• Breastfeeding: Not safe for breastfeeding women; it can harm the newborn baby.
• Alcohol: Avoid alcohol consumption as it can increase the risk of low blood sugar (hypoglycemia) and reduce the medicine's effectiveness.
• Liver/Kidney Impairment: Use with caution in patients with mild to moderate liver or kidney problems. It is not recommended for patients with severe liver disorders or severe kidney disease. Regular monitoring of kidney and liver function tests may be necessary.
• Driving/Operating Machinery: Exercise caution, as low blood sugar levels can lead to drowsiness or confusion, impairing driving ability. Always carry a sugary snack to manage hypoglycemia symptoms.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are taking, as interactions can occur, especially with other anti-diabetic medicines.
• Other Conditions: Discuss pre-existing conditions such as heart disorders, large intestine ulcers, thyroid issues, or recent severe infections with your doctor. It is not recommended for Type 1 diabetes mellitus or Diabetic Ketoacidosis.
• Children and Elderly: Safety and efficacy in children have not been established. Caution is advised for patients over 75 years of age.

Storage: Store VOLIBO R 0.2/1 TABLET at room temperature (below 30°C or between 10°C to 25°C) in a dry place. Protect it from direct sunlight and moisture, and keep it out of the sight and reach of children and pets.

VOLIBO R 0.2/1TABLET, manufactured by SUN PHARMA LABORATORIES LTD., is a combination medication containing Voglibose (0.2 mg) and Repaglinide (1 mg). It is primarily used to manage type 2 diabetes mellitus.

Here are some frequently asked questions about VOLIBO R 0.2/1TABLET:

What is VOLIBO R 0.2/1TABLET used for?

VOLIBO R 0.2/1TABLET is used to treat type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone, or other single antidiabetic medications, are not sufficient to control blood sugar levels. This medicine helps manage blood sugar spikes after meals and reduces the risk of diabetes-related complications such as kidney damage, blindness, and nerve problems.

How does VOLIBO R 0.2/1TABLET work?

This medicine works through the combined action of its two active ingredients:

• Repaglinide: It belongs to the meglitinide class and stimulates the pancreas to release more insulin, which helps lower blood sugar levels after meals.
• Voglibose: It is an alpha-glucosidase inhibitor that slows down the digestion and absorption of carbohydrates in the small intestine. This action prevents sudden and rapid increases in blood glucose after eating.

What is the usual dosage for VOLIBO R 0.2/1TABLET?

The dosage of VOLIBO R 0.2/1TABLET is determined by your doctor based on your medical condition, age, and response to treatment. It is typically taken orally before each main meal, usually 15 to 30 minutes prior. It's crucial to follow your doctor's instructions and not to adjust the dose without consulting them. The maximum daily dose for Repaglinide is usually not more than 16 mg per day.

What are the possible side effects of VOLIBO R 0.2/1TABLET?

Common side effects may include:

• Low blood sugar (hypoglycemia)
• Gastrointestinal issues like abdominal pain, diarrhea, flatulence, nausea, and indigestion.
• Headache
• Dizziness
• Upper respiratory infection
• Back pain and joint pain Most of these side effects are temporary and generally resolve over time. However, if any of these persist or worsen, you should contact your doctor.

Is VOLIBO R 0.2/1TABLET safe during pregnancy or breastfeeding?

VOLIBO R 0.2/1TABLET is generally advised to be used with caution during pregnancy, and some sources state it is unsafe as it may cause harm to the unborn baby. It is also probably unsafe to use during breastfeeding as it can harm the newborn. It should only be used if clearly needed, and risks versus benefits should be discussed with your doctor.

Can VOLIBO R 0.2/1TABLET be taken with other medications?

VOLIBO R 0.2/1TABLET can interact with other medications. It is important to inform your doctor about all other medicines, supplements, or herbal products you are taking. Significant interactions include:

• Other antidiabetic medications (e.g., metformin, insulin): May increase the risk of hypoglycemia.
• Beta-blocker medications (e.g., metoprolol).
• Painkillers (e.g., aspirin).
• Certain enzyme inhibitors or inducers (e.g., CYP3A4 inhibitors like ketoconazole, clarithromycin, or inducers; CYP2C8 inhibitors/inducers).
• Alcohol can increase the risk of low blood sugar and a serious condition called Lactic Acidosis, so its intake should be limited or avoided.

What precautions should be taken while using VOLIBO R 0.2/1TABLET?

Several precautions should be observed:

• Contraindications: Do not take this medicine if you have type 1 diabetes, severe liver disease, diabetic ketoacidosis, or certain gastrointestinal disorders like inflammatory bowel disease or intestinal obstruction.
• Kidney and Liver Health: Use with caution if you have mild to moderate kidney or liver impairment. It is not recommended in severe cases, and regular monitoring of kidney function may be necessary.
• Hypoglycemia: Be aware of the symptoms of low blood sugar (e.g., sweating, dizziness, confusion, tremors) and always carry some sugary food or drink to manage it.
• Driving/Operating Machinery: Due to potential fluctuations in blood sugar, which can cause blurred vision or dizziness, exercise caution when driving or operating machinery.
• Lifestyle: This medication is part of a treatment program that includes a healthy diet, regular exercise, and weight management.

What happens if a dose of VOLIBO R 0.2/1TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you skip a meal, you should also skip the corresponding dose of this medicine to avoid low blood sugar levels.

How should VOLIBO R 0.2/1TABLET be stored?

VOLIBO R 0.2/1TABLET should be stored in a cool place, typically between 10ºC to 25ºC or below 30ºC. Keep the medicine in a closed container, away from heat, moisture, and direct light.