Olkem Trio 6.25 Mg Tablet (10 Tab)

OLKEM TRIO 6.25 MG TABLET

OLKEM TRIO 6.25 MG TABLET, manufactured by Alkem Laboratories Ltd., is a combination medication used to manage hypertension, commonly known as high blood pressure.

Composition Each tablet contains:

• Olmesartan Medoxomil: 20 mg
• Cilnidipine: 10 mg
• Chlorthalidone: 6.25 mg

Uses Olkem Trio 6.25 Tablet is primarily prescribed for the treatment of hypertension (high blood pressure), especially when a single medication is insufficient to control blood pressure levels. It helps to lower high blood pressure by relaxing blood vessels and aiding in the removal of excess water and electrolytes, thereby reducing the risk of serious cardiovascular events such as heart attacks and strokes. It may also help manage kidney complications associated with diabetes and high blood pressure.

Dosage and Administration This medicine should be taken orally as directed by a physician. It is recommended to swallow the tablet whole with a glass of water, without crushing, chewing, or breaking it. Taking Olkem Trio 6.25 Tablet with food is advisable. For best results, it should be taken at the same time each day. Due to its diuretic component, it is generally recommended to avoid taking it within four hours of bedtime to prevent sleep disturbances.

Side Effects Common side effects include ankle swelling (peripheral edema), headache, dizziness, tiredness, palpitations, sleepiness, increased blood uric acid levels, glucose intolerance, altered taste perception, flushing, and upset stomach. Other reported side effects include nausea, back pain, diarrhea, and stomach pain. Most side effects are usually temporary; however, if any persist, worsen, or become bothersome, medical consultation is advised. Dehydration can occur, so maintaining good hydration is important.

Precautions Olkem Trio 6.25 Tablet is contraindicated in individuals with known allergies to its components, low blood pressure (hypotension), a history of heart attack, severe kidney or liver disease, cardiogenic shock, and aortic stenosis. It is unsafe for use during pregnancy and generally not recommended for breastfeeding mothers without medical advice. Patients with kidney problems, liver disease, diabetes, or those taking Aliskiren should use this medication with caution and under medical supervision. Alcohol, grapefruit juice, and St. John's wort should be avoided during treatment. Regular monitoring of electrolytes, kidney function, and blood sugar levels may be required. Due to potential dizziness, caution is advised when driving or operating machinery.

Storage Store Olkem Trio 6.25 Tablet below 25°C or 30°C in a cool and dry place, away from direct sunlight, heat, and moisture. Keep out of the reach of children and pets.

What is Olkem Trio 6.25 MG Tablet used for?

Olkem Trio 6.25 MG Tablet is primarily used to treat hypertension, also known as high blood pressure. It is a combination medication especially useful when a single medicine is not enough to control blood pressure effectively. By lowering high blood pressure, it helps reduce the risk of serious health issues like heart attacks, strokes, and kidney problems.

How does Olkem Trio 6.25 MG Tablet work?

Olkem Trio 6.25 MG Tablet contains three active ingredients: Olmesartan medoxomil, Cilnidipine, and Chlorthalidone.

• Olmesartan medoxomil is an angiotensin receptor blocker (ARB) that works by blocking a hormone called angiotensin, which helps relax and widen blood vessels. This allows blood to flow more smoothly and the heart to pump more efficiently.
• Cilnidipine is a calcium channel blocker (CCB) that works by blocking calcium channels in the heart's blood vessels. This relaxes the blood vessels, reduces the heart's workload, and makes it more efficient at pumping blood.
• Chlorthalidone is a diuretic (often called a "water pill") that helps the body remove excess water and certain electrolytes, such as salts, through increased urine production. This reduces blood volume and, in turn, lowers blood pressure.

Together, these ingredients effectively lower blood pressure and help maintain overall heart health.

What is the usual dosage for Olkem Trio 6.25 MG Tablet?

The dosage and duration of Olkem Trio 6.25 MG Tablet should be strictly followed as prescribed by your doctor. It is typically taken once daily with food, preferably at the same time each day for best results. Do not crush, chew, or break the tablet; swallow it whole with a glass of water.

What are the possible side effects of Olkem Trio 6.25 MG Tablet?

Common side effects may include ankle swelling (peripheral edema), headache, dizziness, tiredness, and altered taste perception. Some individuals might also experience palpitations, sleepiness, flushing (a sense of warmth), upset stomach, increased blood uric acid levels, or glucose intolerance. Most side effects are not severe and often resolve as your body adjusts to the medication. However, if any side effects are bothersome, worsen, or persist, consult your doctor.

Is Olkem Trio 6.25 MG Tablet safe during pregnancy or breastfeeding?

Olkem Trio 6.25 MG Tablet is generally considered unsafe to use during pregnancy as there is clear evidence of risk to the developing baby. If you are pregnant or planning to conceive, you should consult your doctor immediately.

For breastfeeding mothers, the components of this medicine may pass into breast milk, and its effect on the infant is not well known. It is advisable to seek medical advice before taking this medication while breastfeeding.

Can Olkem Trio 6.25 MG Tablet be taken with other medications?

It is crucial to inform your doctor about all other medications, herbal preparations, and supplements you are currently taking to avoid potential interactions. You should avoid taking grapefruit juice, St. John's wort, and alcohol with this medication, as they can lead to adverse effects. Concomitant use with Aliskiren (another blood pressure medicine), especially in patients with diabetes or kidney problems, is not recommended due to increased risks of kidney damage, low blood pressure, and high potassium levels.

What precautions should be taken while on Olkem Trio 6.25 MG Tablet?

• Avoid sudden movements: The medication can cause dizziness, so get up slowly when rising from a sitting or lying position.
• Hydration: Drink plenty of fluids to counteract potential dehydration, muscle weakness, dry mouth, and excessive thirst, especially due to the diuretic component.
• Alcohol: Avoid consuming alcohol as it can increase drowsiness, dizziness, and risk of low blood pressure.
• Driving/Operating Machinery: Due to possible dizziness or tiredness, avoid driving or operating heavy machinery until you know how the medicine affects you.
• Pre-existing conditions: Inform your doctor if you have any liver, kidney, or heart conditions, diabetes, gout, or electrolyte imbalances.
• Regular monitoring: Your doctor may recommend regular monitoring of your blood pressure, kidney function, electrolyte levels (potassium, sodium, magnesium), and blood sugar levels.
• Do not stop abruptly: Do not stop taking this medicine without consulting your doctor, even if you feel well, as sudden discontinuation can lead to a rise in blood pressure and increase the risk of heart-related issues.

What happens if a dose is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Olkem Trio 6.25 MG Tablet be stored?

Olkem Trio 6.25 MG Tablet should be stored in a cool and dry place, away from direct sunlight, heat, and moisture. Keep it out of the reach of children and pets. It is generally recommended to store it below 25°C or 30°C.