Sitaglodm Tab

SITAGLO DM TABLET by ARISTO PHARMA

SITAGLO DM Tablet is an oral anti-diabetic medication manufactured by Aristo Pharma, primarily used for the management of Type 2 Diabetes Mellitus. It is a combination therapy designed to improve blood sugar control in adults, often when diet and exercise alone are insufficient or when single or dual therapies are inadequate.

• Name:

  • Brand Name: Sitaglo DM Tablet, Sitaglo DM Forte Tablet (variant with different strengths).
  • Manufacturer: Aristo Pharmaceuticals Pvt Ltd.

• Composition: SITAGLO DM Tablet typically contains a triple combination of active ingredients:

  • Dapagliflozin: 10mg
  • Sitagliptin: 50mg or 100mg
  • Metformin: 500mg (may be extended-release) These work synergistically to lower blood glucose levels. Dapagliflozin promotes the removal of excess sugar through urine. Sitagliptin increases natural substances that lower blood sugar and enhances insulin release. Metformin reduces sugar production by the liver and delays sugar absorption from the intestines.

• Uses:

  • Type 2 Diabetes Management: Used to improve glycemic control in adults with Type 2 Diabetes Mellitus as an adjunct to diet and exercise.
  • Cardiovascular and Kidney Protection: Helps lower the risk of heart failure and diabetic kidney disease in some patients by improving vascular function and reducing albuminuria.
  • Prevention of Complications: Aims to prevent diabetes-related complications such as kidney damage, eye damage, nerve problems, and cardiovascular risks.

• Dosage and Administration:

  • Take SITAGLO DM Tablet orally as advised by your doctor, usually with meals to reduce stomach upset.
  • Swallow the tablet whole with water; do not crush, break, or chew it.
  • Take at the same time each day for best results. The dosage will be determined by your doctor based on your medical condition and response to treatment. Do not exceed the recommended dose.

• Side Effects:

  • Common Side Effects: Vomiting, nausea, abdominal pain, headache, stomach upset, urinary tract infection, nasal congestion, sore throat, upper respiratory tract infection, diarrhea, and weakness.
  • Serious Side Effects (rare but require immediate medical attention): Lactic acidosis (weakness, breathing difficulty, stomach pain), ketoacidosis (nausea, vomiting, confusion, fruity breath), pancreatitis (severe stomach pain, nausea), severe allergic reactions (rash, swelling, breathing problems), kidney problems, and severe joint pain. Hypoglycemia (low blood sugar) can occur, especially when combined with other antidiabetic medicines or alcohol.

• Precautions:

  • Not recommended for Type 1 diabetes or diabetic ketoacidosis.
  • Inform your doctor about any history of liver or kidney disease, severe breathing problems, blood problems, pancreatitis, or gallstones.
  • Avoid alcohol consumption as it increases the risk of hypoglycemia and lactic acidosis.
  • Consult your doctor if you are pregnant or breastfeeding, as its use is generally not recommended during these periods.
  • Not recommended for children below 18 years of age.
  • Tell your doctor about all other medications, vitamins, and herbal supplements you are taking, as interactions can occur.

• Storage:

  • Store in a cool and dry place, away from sunlight.
  • Keep out of the sight and reach of children.
  • Store below 30°C.

What is SITAGLODM TAB used for?

SITAGLODM TAB, manufactured by Aristo Pharma, is an oral anti-diabetic medicine primarily used for the management of type 2 diabetes mellitus. It helps control high blood sugar levels and can be part of a comprehensive treatment plan including diet and exercise. The medication aims to prevent serious complications associated with diabetes, such as kidney damage, eye problems, nerve issues, and cardiovascular complications.

How does SITAGLODM TAB work?

SITAGLODM TAB contains a combination of Sitagliptin and Metformin. Sitagliptin is a DPP-4 inhibitor that increases the levels of natural substances called incretin hormones. These hormones stimulate insulin release and decrease glucagon levels, thereby helping to lower blood sugar. Metformin, a biguanide, works by reducing glucose production in the liver and improving the body's sensitivity to insulin, leading to better glucose uptake by muscles and tissues. Together, these ingredients provide dual-action control of blood sugar.

What is the usual dosage for SITAGLODM TAB?

SITAGLODM TAB should be taken orally with meals to minimize stomach upset. It is generally recommended to swallow the tablet whole with water and not to crush or chew it. For best results, it should be taken at the same time each day, and the exact dosage and frequency should be strictly followed as directed by your doctor. For example, a common dosage for a Sitagliptin 50mg/Metformin 500mg combination might be twice daily.

What are the possible side effects of SITAGLODM TAB?

Common side effects may include nausea, vomiting, stomach discomfort, diarrhea, indigestion, headache, dizziness, and upper respiratory tract infection. Rarely, more serious side effects can occur, such as low blood sugar (hypoglycemia), especially if taken with other anti-diabetic drugs, or lactic acidosis, which is a rare but serious condition associated with Metformin.

Is SITAGLODM TAB safe during pregnancy or breastfeeding?

SITAGLODM TAB is generally not recommended during pregnancy or breastfeeding. Sitagliptin, one of the active ingredients, has limited information regarding its effects on a developing baby, and it is not known how much passes into breast milk. If you are pregnant, planning to become pregnant, or breastfeeding, it is crucial to consult your doctor to review your treatment, as they may suggest safer alternative medications.

Can SITAGLODM TAB be taken with other medications?

Caution should be exercised when taking SITAGLODM TAB with other medications. Combining it with other anti-diabetic drugs, such as insulin or sulfonylureas, can increase the risk of hypoglycemia (low blood sugar). It's important to inform your doctor about all other medicines, including herbal tonics and supplements, to avoid potential interactions. Alcohol consumption should also be avoided as it can increase the risk of lactic acidosis.

What precautions should be taken while using SITAGLODM TAB?

Patients with kidney or liver problems should use SITAGLODM TAB with caution, and regular monitoring of kidney function is advised. It is not recommended for patients with type 1 diabetes or diabetic ketoacidosis. Inform your doctor if you have a history of heart disease, pancreatic issues, or if you consume alcohol regularly. Avoid excessive alcohol consumption while on this medicine. If you are scheduled for surgery or an X-ray procedure involving an injected dye, inform your doctor as you may need to temporarily stop taking Metformin.

What happens if a dose of SITAGLODM TAB is missed?

If you miss a dose of SITAGLODM TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should SITAGLODM TAB be stored?

SITAGLODM TAB should be stored in a cool, dry place, away from direct sunlight, and out of the reach of children. Ensure it is not used past its expiry date.