Esofine Dsr Capsules ( 15 Cap )

ESOFINE DSR CAPSULES

ESOFINE DSR CAPSULES are a medication manufactured by MACLEODS PHARMACEUTICALS LTD., primarily used to manage various gastrointestinal conditions.

• Composition: Each capsule contains Esomeprazole (40mg) and Domperidone (30mg). Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production, while Domperidone is a prokinetic that increases the movement of the stomach and intestines.

• Uses: ESOFINE DSR CAPSULES are prescribed for adults to treat:

  • Gastroesophageal Reflux Disease (GERD) and acid reflux, alleviating symptoms like heartburn, stomach pain, and irritation.
  • Stomach ulcers (gastric and duodenal ulcers) and peptic ulcer disease.
  • Zollinger-Ellison syndrome, a condition causing excessive stomach acid production due to pancreatic tumors.
  • Related symptoms such as nausea, vomiting, acidity, indigestion, burping, and bloating.

• Dosage and Administration: It is generally advised to take ESOFINE DSR CAPSULES on an empty stomach, ideally an hour before a meal, usually in the morning. The capsule should be swallowed whole with water; it should not be chewed, crushed, or broken. The dosage and duration of treatment are determined by a doctor based on the patient's medical condition.

• Side Effects: Common side effects include:

  • Dry mouth
  • Stomach pain
  • Diarrhea or constipation
  • Headache
  • Flatulence (gas)
  • Dizziness or giddiness Long-term use may lead to a decrease in magnesium and vitamin B12 levels and might increase the risk of bone fractures.

• Precautions:

  • Inform your doctor if you have allergies to Esomeprazole, Domperidone, or any other ingredients.
  • Caution is advised for patients with severe kidney, liver, or heart disease.
  • Not recommended for patients with gastric cancer, a blockage, tear, or bleeding in the digestive system, or a pituitary gland tumor.
  • Pregnant or breastfeeding women should consult their doctor before use.
  • Avoid alcohol consumption as it can increase drowsiness and stomach acid production.
  • This medicine may cause dizziness, so avoid driving or operating machinery if affected.
  • Inform your doctor about all other medications you are taking, as drug interactions can occur, especially with certain antifungals, antibiotics, HIV medications, and heart medicines.
  • Prolonged use may require monitoring of magnesium and vitamin B12 levels.

• Storage: Store ESOFINE DSR CAPSULES in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. Typically, it should be stored below 25°C or 30°C.

ESOFINE DSR CAPSULES contain Esomeprazole and Domperidone. This combination medicine is widely used to treat various acidity-related conditions.

What is ESOFINE DSR CAPSULES used for?

ESOFINE DSR CAPSULES are primarily used to treat Gastroesophageal Reflux Disease (GERD), also known as acid reflux. This condition involves acid flowing back from the stomach into the food pipe, causing symptoms like heartburn, chest discomfort, and acidity. It is also effective in treating stomach ulcers, duodenal ulcers, Zollinger-Ellison syndrome (a condition with excessive stomach acid production), and indigestion.

How do ESOFINE DSR CAPSULES work?

ESOFINE DSR CAPSULES combine two active ingredients: Esomeprazole and Domperidone.

• Esomeprazole is a proton pump inhibitor (PPI) that works by blocking a specific enzyme called the gastric proton pump in the stomach wall. This action reduces the production of stomach acid.
• Domperidone is a prokinetic agent that increases the movement and contractions of the stomach and intestines. This helps food move more easily through the digestive tract and prevents acid from flowing back into the food pipe. Together, they reduce acid production and improve gastrointestinal motility, providing relief from acidity-related problems.

What is the usual dosage for ESOFINE DSR CAPSULES?

ESOFINE DSR CAPSULES should be taken as advised by your doctor, usually 30 minutes to one hour before a meal, preferably in the morning. The capsules should be swallowed whole with water and not chewed, crushed, or broken. Do not exceed the prescribed dose.

What are the possible side effects of ESOFINE DSR CAPSULES?

Common side effects may include dry mouth, stomach pain, diarrhea, headache, and flatulence (gas). Other possible side effects can include dizziness, nausea, constipation, or giddiness. Most of these side effects are temporary and usually resolve over time. However, if they persist or worsen, it is important to consult your doctor.

Is it safe during pregnancy or breastfeeding?

Pregnancy: ESOFINE DSR CAPSULES should be used during pregnancy only if considered necessary by a physician, as there is limited information about its safety in human pregnancy. Breastfeeding: ESOFINE DSR CAPSULES may pass into breast milk in small amounts and might affect the baby. It is generally considered unsafe to use during breastfeeding, though some sources state it should be used with caution. Consult your doctor if you are pregnant or breastfeeding.

Can it be taken with other medications?

ESOFINE DSR CAPSULES can interact with certain other medications. It should not be taken with anti-HIV medications like nelfinavir, atazanavir, or rilpivirine, as it can affect their absorption. Concomitant use with certain antifungals (e.g., ketoconazole, itraconazole), antibiotics (e.g., clarithromycin, erythromycin), and medicines for irregular heartbeats (e.g., disopyramide, amiodarone) or mental problems may also lead to interactions. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

What precautions should be taken?

• Do not take ESOFINE DSR CAPSULES if you are allergic to esomeprazole, domperidone, or any of its ingredients.
• Inform your doctor if you have severe kidney, heart, or liver disease, a blockage or tear in the intestine, bleeding in the digestive system, or a pituitary gland tumor (prolactinoma).
• Long-term treatment may lead to low magnesium or vitamin B12 levels and might increase the risk of bone fractures. Your doctor may recommend regular monitoring and supplements if needed.
• Avoid alcohol consumption as it can increase stomach acid production and worsen symptoms.
• This medicine may cause dizziness or drowsiness; avoid driving or operating heavy machinery if you feel unwell or are not alert.
• Not recommended for children as safety has not been established.

What happens if a dose is missed?

If you miss a dose of ESOFINE DSR CAPSULES, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should it be stored?

Store ESOFINE DSR CAPSULES in a cool and dry place, away from direct sunlight, moisture, and heat. Keep it out of sight and reach of children.